Zobrazeno 1 - 10
of 34
pro vyhledávání: '"A A Zakhariants"'
Autor:
Osipyants, Andrey I., Poloznikov, Andrey A., Smirnova, Natalya A., Hushpulian, Dmitry M., Khristichenko, Anna Yu., Chubar, Tatiana A., Zakhariants, Arpenik A., Ahuja, Manuj, Gaisina, Irina N., Thomas, Bobby, Brown, Abe M., Gazaryan, Irina G., Tishkov, Vladimir I.
Publikováno v:
In Biochimie April 2018 147:46-54
Autor:
Poloznikov, A.A., Zakhariants, A.A., Nikulin, S.V., Smirnova, N.A., Hushpulian, D.M., Gaisina, I.N., Tonevitsky, A.G., Tishkov, V.I., Gazaryan, I.G.
Publikováno v:
In Biochimie February 2017 133:74-79
Autor:
Natalia L. Klyachko, Anthony M. C. Brown, Valentina A. Shchedrina, A A Zakhariants, Irina G. Gazaryan, S V Kazakov
Publikováno v:
Biochemistry (Moscow). 85:908-919
Elevation of intracellular Zn2+ following ischemia contributes to cell death by affecting mitochondrial function. Zn2+ is a differential regulator of the mitochondrial enzyme lipoamide dehydrogenase (LADH) at physiological concentrations (Ka = 0.1 µ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b039bf0cf669acfc3dd055f8c8cd6deb
https://doi.org/10.1134/s0006297920080064
https://doi.org/10.1134/s0006297920080064
Autor:
T. A. Chubar, Vladimir I. Tishkov, Yu. Khristichenko, Irina G. Gazaryan, Dmitry M. Hushpulian, Andrey A. Poloznikov, N. A. Smirnova, A. A. Zakhariants
Publikováno v:
Moscow University Chemistry Bulletin. 75:172-178
Reporter vectors expressing of amino acid residues 16–96 and 16–85 from Neh2-domain of Nrf2 transcription factor fused to firefly luciferase have been constructed. Cell lines stably expressing the above reporter constructs as well as an earlier d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::423149465fdc58f0b498981736bf933e
https://doi.org/10.3103/s0027131420030062
https://doi.org/10.3103/s0027131420030062
Autor:
Vladimir I. Tishkov, A. Yu. Khristichenko, D. M. Hushpulian, Sergey Kazakov, N. A. Smirnova, Andrey A. Poloznikov, Irina G. Gazaryan, A. A. Zakhariants
Publikováno v:
Moscow University Chemistry Bulletin. 74:180-185
Cell-based reporters expressing luciferase fusions with transcription factors or their protein stability domains can be considered as microbioreactors providing a way to directly monitor the stability of the luciferase labeled transcription factor or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c607d0139fb3a3a39056eebedb573ae9
https://doi.org/10.3103/s0027131419040047
https://doi.org/10.3103/s0027131419040047
Autor:
I N Gazizov, Anna Yu. Khristichenko, A. A. Zakhariants, Andrey A. Poloznikov, Dmitry M. Hushpulian, Vladimir I. Tishkov, Irina G. Gazaryan, Sergey Nikulin
Publikováno v:
Drug Metabolism Letters. 13:45-52
Background: “Branched tail” oxyquinolines, and adaptaquin in particular, are potent HIF prolyl hydroxylase inhibitors showing promising results in in vivo hemorrhagic stroke models. The further improvement of the potency resulted in identificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496f81b6e9b91599479aa34eb1a7bb8e
https://doi.org/10.2174/1872312813666181129100950
https://doi.org/10.2174/1872312813666181129100950
Autor:
Sergey Nikulin, N. A. Smirnova, A. Yu. Khristichenko, Andrey A. Poloznikov, Irina G. Gazaryan, A. A. Zakhariants, T. A. Chubar, A. I. Osipyants, D. M. Hushpulian, Vladimir I. Tishkov
Publikováno v:
Russian Chemical Bulletin. 67:150-156
Reporters expressing fusion proteins of HIF2 and HIF3 C-terminal oxygen degradable domain (ODD) with the firefly luciferase, HIF2 ODD-luc and HIF3 ODD-luc, were constructed and briefly characterized. Stable neuroblastoma cell lines expressing either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07620687cf9b2af3000f70bc2857f0a2
https://doi.org/10.1007/s11172-018-2051-5
https://doi.org/10.1007/s11172-018-2051-5
Autor:
A. I. Osipyants, A. Yu. Khristichenko, N. A. Smirnova, Sergey Nikulin, Andrey A. Poloznikov, Irina G. Gazaryan, Vladimir I. Tishkov, A. A. Zakhariants
Publikováno v:
Moscow University Chemistry Bulletin. 73:13-18
Activation of antihypoxic program under the action of a number of transition and heavy metals has been studied using cell-based HIF1 ODD-luc and HRE-luc reporters. It has been demonstrated that Au3+, Pb2+, Sn2+, Hg2+ are weak HIF1 ODD-luc activators,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4795a11dd8b6e94442143cb80444e8eb
https://doi.org/10.3103/s0027131418020128
https://doi.org/10.3103/s0027131418020128
Akademický článek
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Autor:
N. A. Smirnova, Vladimir I. Tishkov, Irina G. Gazaryan, Sergey Nikulin, Andrey A. Poloznikov, A. Yu. Khristichenko, A. I. Osipyants, A. A. Zakhariants, T. A. Chubar, D. M. Hushpulian
Publikováno v:
Biochemistry (Moscow). 82:1207-1214
An organism naturally responds to hypoxia via stabilization of hypoxia-inducible factor (HIF). There are three isoforms of HIFα subunits whose stability is regulated by three isozymes of HIF prolyl hydroxylase (PHD1-3). Despite intense studies on re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c5f5201984a83f5e6ee601898213d2
https://doi.org/10.1134/s0006297917100145
https://doi.org/10.1134/s0006297917100145