Zobrazeno 1 - 10
of 1 660
pro vyhledávání: '"A A Brakhage"'
Autor:
Sarah Dellière, Camille Chauvin, Sarah Sze Wah Wong, Markus Gressler, Valentina Possetti, Raffaella Parente, Thierry Fontaine, Thomas Krüger, Olaf Kniemeyer, Jagadeesh Bayry, Agostinho Carvalho, Axel A. Brakhage, Antonio Inforzato, Jean-Paul Latgé, Vishukumar Aimanianda
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Pentraxin 3 (PTX3), a long pentraxin and a humoral pattern recognition molecule (PRM), has been demonstrated to be protective against Aspergillus fumigatus, an airborne human fungal pathogen. We explored its mode of interaction with A. fumig
Externí odkaz:
https://doaj.org/article/b58012077bfc4de9af83513f2000d485
Autor:
Sarah König, Josefine Schroeder, Thorsten Heinekamp, Axel A. Brakhage, Bettina Löffler, Beatrice Engert, Christina Ehrhardt
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionInfluenza-associated pulmonary aspergillosis is associated with high mortality rates and limited treatment options. The current standard practice involves treating each pathogen separately. However, the use of antifungal drugs can lead to
Externí odkaz:
https://doaj.org/article/02a2e6c140194520af141585775a02d9
Autor:
Norman van Rhijn, Can Zhao, Narjes Al-Furaiji, Isabelle S. R. Storer, Clara Valero, Sara Gago, Harry Chown, Clara Baldin, Rachael-Fortune Grant, Hajer Bin Shuraym, Lia Ivanova, Olaf Kniemeyer, Thomas Krüger, Elaine Bignell, Gustavo H. Goldman, Jorge Amich, Daniela Delneri, Paul Bowyer, Axel A. Brakhage, Hubertus Haas, Michael J. Bromley
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract More than 10 million people suffer from lung diseases caused by the pathogenic fungus Aspergillus fumigatus. Azole antifungals represent first-line therapeutics for most of these infections but resistance is rising, therefore the identificat
Externí odkaz:
https://doaj.org/article/b48ee6e7b3ac4ef8ac88712d8df32311
Autor:
Torres-Gómez, Héctor, Keiff, François, Hortschansky, Peter, Bernal, Freddy, Kerndl, Valerie, Meyer, Florian, Messerschmidt, Nina, Dal Molin, Michael, Krüger, Thomas, Rybniker, Jan, Brakhage, Axel A., Kloss, Florian
Publikováno v:
In European Journal of Medicinal Chemistry 5 December 2024 279
Autor:
Endrews Delbaje, Patrícia Alves de Castro, Dante G. Calise, Niu Mengyao, Maria Augusta Crivelente Horta, Daniel Yuri Akiyama, João Guilherme Pontes, Taícia Fill, Olaf Kniemeyer, Thomas Krüger, Axel A. Brakhage, Koon Ho Wong, Nancy P. Keller, Gustavo H. Goldman
Publikováno v:
Journal of Fungi, Vol 10, Iss 11, p 749 (2024)
Aspergillus fumigatus can cause invasive pulmonary aspergillosis (IPA). Fungicidal azoles and fungistatic caspofungin (CAS) are the first- and second-line therapies, respectively, used to treat IPA. Treatment of A. fumigatus with CAS or micafungin in
Externí odkaz:
https://doaj.org/article/a75f109a86b14366a6f4842cc83e603c
Autor:
Sebastian Schruefer, Annica Pschibul, Sarah Sze Wah Wong, Tongta Sae-Ong, Thomas Wolf, Sascha Schäuble, Gianni Panagiotou, Axel A. Brakhage, Vishukumar Aimanianda, Olaf Kniemeyer, Frank Ebel
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-25 (2023)
Abstract Background Aspergillus fumigatus is a major fungal pathogen that causes severe problems due to its increasing resistance to many therapeutic agents. Fludioxonil is a compound that triggers a lethal activation of the fungal-specific High Osmo
Externí odkaz:
https://doaj.org/article/8304e9c5c1934c3f861318b175955848
Autor:
Norman van Rhijn, Can Zhao, Narjes Al-Furaiji, Isabelle S. R. Storer, Clara Valero, Sara Gago, Harry Chown, Clara Baldin, Rachael-Fortune Grant, Hajer Bin Shuraym, Lia Ivanova, Olaf Kniemeyer, Thomas Krüger, Elaine Bignell, Gustavo H. Goldman, Jorge Amich, Daniela Delneri, Paul Bowyer, Axel A. Brakhage, Hubertus Haas, Michael J. Bromley
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/e844ea14cdc94abd9b868de3f1484f0e
Autor:
König, Sarah, Schroeder, Josefine, Nietzsche, Sandor, Heinekamp, Thorsten, Brakhage, Axel A., Zell, Roland, Löffler, Bettina, Ehrhardt, Christina
Publikováno v:
In Microbes and Infection March-April 2024 26(3)
Autor:
Mohammad H. Mirhakkak, Xiuqiang Chen, Yueqiong Ni, Thorsten Heinekamp, Tongta Sae-Ong, Lin-Lin Xu, Oliver Kurzai, Amelia E. Barber, Axel A. Brakhage, Sebastien Boutin, Sascha Schäuble, Gianni Panagiotou
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Aspergillus fumigatus, an opportunistic human pathogen, frequently infects the lungs of people with cystic fibrosis and is one of the most common causes of infectious-disease death in immunocompromised patients. Here, we construct 252 strain
Externí odkaz:
https://doaj.org/article/e8d5fb99e5474f61bb345e85e225884e
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