Zobrazeno 1 - 10
of 1 250
pro vyhledávání: '"A A, Tejpar"'
Autor:
Jinhai Deng, Teng Pan, Dan Wang, Yourae Hong, Zaoqu Liu, Xingang Zhou, Zhengwen An, Lifeng Li, Giovanna Alfano, Gang Li, Luigi Dolcetti, Rachel Evans, Jose M Vicencio, Petra Vlckova, Yue Chen, James Monypenny, Camila Araujo De Carvalho Gomes, Gregory Weitsman, Kenrick Ng, Caitlin McCarthy, Xiaoping Yang, Zedong Hu, Joanna C Porter, Christopher J Tape, Mingzhu Yin, Fengxiang Wei, Manuel Rodriguez-Justo, Jin Zhang, Sabine Tejpar, Richard Beatson, Tony Ng
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2080-2108 (2024)
Abstract Chemotherapy, the standard of care treatment for cancer patients with advanced disease, has been increasingly recognized to activate host immune responses to produce durable outcomes. Here, in colorectal adenocarcinoma (CRC) we identify oxal
Externí odkaz:
https://doaj.org/article/5559931ff7c94961b54686129b587544
Autor:
Lies van Baarle, Veronica De Simone, Linda Schneider, Sneha Santhosh, Saeed Abdurahiman, Francesca Biscu, Reiner Schneider, Lisa Zanoletti, Renata Siqueira de Mello, Sara Verbandt, Zedong Hu, Michelle Stakenborg, Bo-Jun Ke, Nathalie Stakenborg, Raquel Salvador Laureano, Balbina García-Reyes, Jonas Henn, Marieta Toma, Maxime Vanmechelen, Guy Boeckxstaens, Frederik De Smet, Abhishek D. Garg, Sales Ibiza, Sabine Tejpar, Sven Wehner, Gianluca Matteoli
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Enteric glia have been recently recognized as key components of the colonic tumor microenvironment indicating their potential role in colorectal cancer pathogenesis. Although enteric glia modulate immune responses in other intestinal disease
Externí odkaz:
https://doaj.org/article/2d23e62003474368a9d6f0fc32cd8ece
Autor:
Jonas Langerud, Ina A. Eilertsen, Seyed H. Moosavi, Solveig M. K. Klokkerud, Henrik M. Reims, Ingeborg F. Backe, Merete Hektoen, Ole H. Sjo, Marine Jeanmougin, Sabine Tejpar, Arild Nesbakken, Ragnhild A. Lothe, Anita Sveen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Intra-tumor heterogeneity compromises the clinical value of transcriptomic classifications of colorectal cancer. We investigated the prognostic effect of transcriptomic heterogeneity and the potential for classifications less vulnerable to h
Externí odkaz:
https://doaj.org/article/d4d1453bbc3e48efb2d29292fe31b570
Autor:
Kate E. Stanley, Tatjana Jatsenko, Stefania Tuveri, Dhanya Sudhakaran, Lore Lannoo, Kristel Van Calsteren, Marie de Borre, Ilse Van Parijs, Leen Van Coillie, Kris Van Den Bogaert, Rodrigo De Almeida Toledo, Liesbeth Lenaerts, Sabine Tejpar, Kevin Punie, Laura Y. Rengifo, Peter Vandenberghe, Bernard Thienpont, Joris Robert Vermeesch
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Circulating cell-free DNA (cfDNA) fragments have characteristics that are specific to the cell types that release them. Current methods for cfDNA deconvolution typically use disease tailored marker selection in a limited number of bulk tissu
Externí odkaz:
https://doaj.org/article/c984c127506a411093b6c0f89977a486
Autor:
Carballal, Sabela, Moreira, Leticia, Torres, Sonia, Kumari, Hardeep, Brunori, Angelo, Sanchez, Ariadna, Ocaña, Teresa, Castillo, Joaquin, Saez-Gordoa, Karmele, Cuatrecasas, Miriam, Rivas, Eva, Vizuete, Maria, Carnicer, Silvia, Cuadrado, Rosa, Puzzono, Marta, Bianchi, Paolo, Laghi, Luigi, Dal Buono, Arianna, Giatti, Valentina, Nicoletti, Rosangela, Marwitz, Tim, Van Beekum, Katrin, Mangas-Sanjuan, Carolina, Martinez-Sempere, Juan, Serrano, Eva, Carretero, Cristina, Ortiz, Oswaldo a, b, Daca-Alvarez, Maria a, b, Rivero-Sanchez, Liseth a, b, Gimeno-Garcia, Antonio Z d, Carrillo-Palau, Marta d, Alvarez, Victoria e, Ledo-Rodriguez, Alejandro e, Ricciardiello, Luigi f, g, h, Pierantoni, Chiera f, Hüneburg, Robert i, j, Nattermann, Jacob i, j, Bisschops, Raf k, Tejpar, Sabine k, Huerta, Alain l, Riu Pons, Faust m, Alvarez-Urturi, Cristina m, López-Vicente, Jorge n, Repici, Alessandro o, Hassan, Cessare o, p, Cid, Lucia q, r, Cavestro, Giulia Martina s, Romero-Mascarell, Cristina t, Gordillo, Jordi t, Puig, Ignasi u, v, w, Herraiz, Maite x, Betes, Maite x, Herrero, Jesús y, Jover, Rodrigo z, Balaguer, Francesc a, b, c, *, Pellisé, Maria a, b, c, *, *
Publikováno v:
In The Lancet Gastroenterology & Hepatology September 2024 9(9):802-810
Autor:
Daniel Morales Borràs, Sara Verbandt, Markus Ausserhofer, Gregor Sturm, Jinyeong Lim, Gil Arasa Verge, Isaure Vanmeerbeek, Raquel S. Laureano, Jannes Govaerts, Jenny Sprooten, Yourae Hong, Rebecca Wall, Gert De Hertogh, Xavier Sagaert, Gabriele Bislenghi, André D’Hoore, Albert Wolthuis, Francesca Finotello, Woong-Yang Park, Stefan Naulaerts, Sabine Tejpar, Abhishek D. Garg
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-30 (2023)
Abstract CD8+ T cell activation via immune checkpoint blockade (ICB) is successful in microsatellite instable (MSI) colorectal cancer (CRC) patients. By comparison, the success of immunotherapy against microsatellite stable (MSS) CRC is limited. Litt
Externí odkaz:
https://doaj.org/article/b6bbbd98e72c4ea192406d7073bc5f95
Autor:
Ogasawara, Nobuhiko 1, 11, Kano, Yoshihito 2, 11, Yoneyama, Yosuke 3, Kobayashi, Sakurako 1, Watanabe, Satoshi 1, Kirino, Sakura 1, Velez-Bravo, Fausto D. 4, Hong, Yourae 4, Ostapiuk, Aleksandra 4, Lutsik, Pavlo 5, Onishi, Iichiroh 6, Yamauchi, Shinichi 7, Hiraguri, Yui 1, Ito, Go 8, Kinugasa, Yusuke 7, Ohashi, Kenichi 9, Watanabe, Mamoru 8, Okamoto, Ryuichi 1, Tejpar, Sabine 4, ∗, Yui, Shiro 10, 12, ∗∗
Publikováno v:
In iScience 15 March 2024 27(3)
Autor:
Nobuhiko Ogasawara, Yoshihito Kano, Yosuke Yoneyama, Sakurako Kobayashi, Satoshi Watanabe, Sakura Kirino, Fausto D. Velez-Bravo, Yourae Hong, Aleksandra Ostapiuk, Pavlo Lutsik, Iichiroh Onishi, Shinichi Yamauchi, Yui Hiraguri, Go Ito, Yusuke Kinugasa, Kenichi Ohashi, Mamoru Watanabe, Ryuichi Okamoto, Sabine Tejpar, Shiro Yui
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109247- (2024)
Summary: In normal intestines, a fetal/regenerative/revival cell state can be induced upon inflammation. This plasticity in cell fate is also one of the current topics in human colorectal cancer (CRC). To dissect the underlying mechanisms, we generat
Externí odkaz:
https://doaj.org/article/b7c4b22989424e7d86277299f9e37c54
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Autor:
Hoffman, Steven J., Baral, Prativa, Van Katwyk, Susan Rogers, Sritharan, Lathika, Hughsam, Matthew, Randhawa, Harkanwal, Lin, Gigi, Campbell, Sophie, Campus, Brooke, Dantas, Maria, Foroughian, Neda, Groux, Gaëlle, Gunn, Elliot, Guyatt, Gordon, Habibi, Roojin, Karabit, Mina, Karir, Aneesh, Kruja, Krista, Lavis, John N., Lee, Olivia, Li, Binxi, Nagi, Ranjana, Naicker, Kiyuri, Røttingen, John-Arne, Sahar, Nicola, Srivastava, Archita, Tejpar, Ali, Tran, Maxwell, Zhang, Yu-qing, Zhou, Qi, Poirier, Mathieu J. P.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2022 Aug 01. 119(32), 1-9.
Externí odkaz:
https://www.jstor.org/stable/27171420