Zobrazeno 1 - 10
of 11
pro vyhledávání: '"A A, Skuin'sh"'
Publikováno v:
Bioorganicheskaia khimiia. 11(9)
Modified corticotropin fragment - [Lys11 (Gly)]ACTH-(5-14)- and its cyclic analogue - [cyclo (Glu gamma----epsilon Lys (Gly)] ACTH-(5-14)-undecapeptides have been synthesized by classical approach. The cyclic structure has been fixed by amide bond be
Publikováno v:
Bioorganicheskaia khimiia. 10(10)
A cyclic analogue and the corresponding linear segment of the corticotropin molecule, namely ACTH-(5-14)- and [cyclo (Glu gamma-epsilon Lys)]ACTH-(5-14)-decapeptide, both including the specific and unspecific active centers of the ACTH molecule, have
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 101(3)
Possible hormonal activity of ACTH4-7, a long-acting ACTH4-10 analog (ProGly Pro) was studied. Unlike ACTH5-10 the peptide did not reveal steroidogenic and melanocyte-stimulating activity.
Publikováno v:
Problemy endokrinologii. 26(6)
Publikováno v:
Problemy endokrinologii. 34(3)
[Comparison of structural and functional organization of adrenocorticotropic hormone and wasp kinin]
Autor:
G G, Kublis, E A, Porunkevich, A A, Skuin'sh, N A, Makarova, I P, Misin'sh, V E, Klusha, G I, Chipens
Publikováno v:
Biokhimiia (Moscow, Russia). 42(4)
A comparative study of structural and functional organization of the polypeptides -- ACTH and wasp kinin was made. The effects of fragments Lys 17, 18-ACTH11(-18)-NH2--(I) and WK4(-12)--(II), possessing "common" fragments and a cluster of basic amino
Publikováno v:
Biokhimiia (Moscow, Russia). 42(2)
The influence of ACTH fragments, possessing structural elements, common for certain groups of peptide hormones and kinins--"common" fragments and cluster of basic amino-acids--(Lys 17,18-ACTH 11-18-NH2--I; ACTH 11-13-NH2--II; NH2CO-ACTH18-20-NH2--III
Publikováno v:
Biokhimiia (Moscow, Russia). 47(7)
The steroidogenic and lipolytic activities of ACTH fragments (ACTH11-24--I, ACTH11-19--II, ACTH11-16--III and ACTH 17-24--IV) were studied. Fragments I--IV exert a steroidogenic effect in isolated fasciculata rat adrenal cells at concentrations of 1-
Publikováno v:
Bioorganicheskaia khimiia. 10(6)
Linear and cyclic analogues of the specific active center of the ACTH molecule have been synthesized, viz. [Lis5]ACTH-(5-10)-, [Lys5, cyclo (Gly10----epsilon Lys5)]-ACTH-(5-10)-hexapeptides, [Lys5 (Gly)]ACTH-(5-10)- and [Lys5, Gly11, cyclo (Gly11----
Autor:
E. A. Porunkevich, V. N. Nezavibat'ko, I. P. Ashmarin, M. A. Ponomareva-Stepnaya, A. A. Skuin'sh
Publikováno v:
Bulletin of Experimental Biology and Medicine. 101:255-256