Zobrazeno 1 - 10
of 193
pro vyhledávání: '"A A, Kechin"'
Autor:
Ulyana A. Boyarskih, Andrey A. Kechin, Alyona V. Zyuzyukina, Yevgeny A. Khrapov, Igor P. Oscorbin, Yefim Y. Alexeenok, Galina A. Avdiyuk, Ruslan A. Zukov, Nikolay E. Kushlinskii, Maksim L. Filipenko
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 52, Iss 3, Pp 132-139 (2024)
Background: For effective screening of breast cancer patients for candidates for target therapy with alpelisib, it is necessary to identify activating somatic mutations in the PIK3CA gene by allele specific polymerase chain reaction (PCR); this requi
Externí odkaz:
https://doaj.org/article/066dd6030c43452ba3308b2541346f48
Autor:
Lipunov, V., Kornilov, V., Zhirkov, K., Tyurina, N., Gorbovskoy, E., Vlasenko, D., Simakov, S., Topolev, V., Francile, C., Podesta, R., Podesta, F., Svinkin, D., Budnev, N., Gress, O., Balanutsa, P., Kuznetsov, A., Chasovnikov, A., Serra-Ricart, M., Gabovich, A., Minkina, E., Antipov, G., Svertilov, S., Tlatov, A., Senik, V., Tselik, Yu., Kechin, Ya., Yurkov, V.
Publikováno v:
MNRAS 514, 4, 4980-4987 (2022)
We report on MASTER optical observations of an afterglow-like optical and X-ray transient AT2021lfa/ZTF21aayokph. We detected the initial steady brightening of the transient at 7{\sigma} confidence level. This allowed us to use smooth optical self-si
Externí odkaz:
http://arxiv.org/abs/2302.05924
Autor:
Gridina Maria, Popov Andrey, Shadskiy Artem, Torgunakov Nikita, Kechin Andrey, Khrapov Evgeny, Ryzhkova Oxana, Filipenko Maxim, Fishman Veniamin
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract This study presents a novel approach for mapping global chromatin interactions using S1 nuclease, a sequence-agnostic enzyme. We develop and outline a protocol that leverages S1 nuclease's ability to effectively introduce breaks into both op
Externí odkaz:
https://doaj.org/article/e64f909007a14bb88f42f13fbe48507a
Akademický článek
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Autor:
E. M. Polyanskaya, M. Yu. Fedyanin, U. A. Boyarskikh, A. A. Kechin, E. A. Moroz, E. A. Khrapov, I. P. Oskorobin, D. V. Shamovskaya, V. A. Aliev, Z. Z. Mammadli, A. A. Tryakin, M. L. Filipenko, S. A. Tyulendin
Publikováno v:
Успехи молекулярной онкологии, Vol 9, Iss 2, Pp 32-42 (2022)
Introduction. Studies on non-metastatic colorectal cancer have demonstrated the prognostic role of circulating tumor (ctDNA) after surgery, and the ability to identify patients with the greatest risk of progression. This makes it possible in the futu
Externí odkaz:
https://doaj.org/article/522359f026a74f06bf63b1c526809c20
Autor:
Boyarskikh, Ulyana1 (AUTHOR) boyarskih.u@gmail.com, Kechin, Andrey1 (AUTHOR) max@niboch.nsc.ru, Khrapov, Evgeniy1 (AUTHOR), Fedyanin, Mikhail2 (AUTHOR), Raskin, Grigory3 (AUTHOR) rasking@list.ru, Mukhina, Marina3 (AUTHOR) mukhina@ldc.ru, Kravtsova, Elena3 (AUTHOR), Tsukanov, Aleksey4 (AUTHOR), Achkasov, Sergey4 (AUTHOR), Filipenko, Maksim1 (AUTHOR)
Publikováno v:
Cancers. Oct2023, Vol. 15 Issue 20, p5065. 13p.
Autor:
E. M. Polyanskaya, M. Yu. Fedyanin, U. A. Boyarskikh, A. A. Kechin, E. A. Moroz, A. N. Polyakov, N. E. Kudashkin, D. V. Podluzhniy, E. A. Khrapov, I. P. Oskorobin, D. V. Shamovskaya, V. A. Aliev, Z. Z. Mamedli, A. A. Tryakin, M. L. Filipenko, S. A. Tjulandin
Publikováno v:
Тазовая хирургия и онкология, Vol 12, Iss 1, Pp 27-34 (2022)
Background. Circulating tumor DnA (ctDnA) may act as a potential biomarker for predicting disease progression in patients with colorectal cancer (CRC), which are radically cured or receiving chemotherapy.Objective: to evaluate the sensitivity of the
Externí odkaz:
https://doaj.org/article/99f589873ede4c1ba404acaf9753fe7a
Autor:
Andrey Kechin, Ulyana Boyarskikh, Viktoriya Borobova, Evgeniy Khrapov, Sergey Subbotin, Maxim Filipenko
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16630 (2023)
Detecting copy number variations (CNVs) and alterations (CNAs) in the BRCA1 and BRCA2 genes is essential for testing patients for targeted therapy applicability. However, the available bioinformatics tools were initially designed for identifying CNVs
Externí odkaz:
https://doaj.org/article/92b39e82de944a2a8a77ca646b2c83b0
Publikováno v:
Сибирский онкологический журнал, Vol 20, Iss 6, Pp 120-133 (2022)
Background. The first-generation trk inhibitors, larotrectinib and entrectinib, were approved by the u.s. Food and drug administration (Fda) for the treatment of advanced solid tumors harboring NTRK gene fusions in November 2018 and in august 2019, r
Externí odkaz:
https://doaj.org/article/95352437ab884d28b9d3fa3186cf87a3
Publikováno v:
Oftalʹmologiâ, Vol 18, Iss 4, Pp 840-844 (2021)
Objective: to evaluate the results of corneal collagen crosslinking in children with keratoconus.Patients and methods. Since 2017, 125 children aged 4 to 17 years have been under observation, who have applied to the Eye Microsurgery named after Acade
Externí odkaz:
https://doaj.org/article/f4625fa2ad194c438ca6ee2ec06fbc04