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Akademický článek

eEF1A1 promotes colorectal cancer progression and predicts poor prognosis of patients

Autor: A‐hui Fan, Xiaojuan Zhao, Hao Liu, Danxiu Li, Tongtong Guo, Jiehao Zhang, Lili Duan, Hao Cheng, Yongzhan Nie, Daiming Fan, Xiaodi Zhao, Yuanyuan Lu

Publikováno v: Cancer Medicine, Vol 12, Iss 1, Pp 513-524 (2023)

Abstract Colorectal cancer (CRC) is a major leading cause of cancer mortality worldwide in which dysregulated protein synthesis plays an etiologic role. The eukaryotic elongation factor 1 A1 (eEF1A1) exerts significant effects on protein synthesis by

Externí odkaz: https://doaj.org/article/c966a9a4021c48ef9ea9738f9493095f

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Akademický článek

Multi-perspective comparison of the immune microenvironment of primary colorectal cancer and liver metastases

Autor: Yangsong He, Yanan Han, A-hui Fan, Danxiu Li, Boda Wang, Kun Ji, Xin Wang, Xiaodi Zhao, Yuanyuan Lu

Publikováno v: Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)

Abstract Background Liver metastases are a major contributor to the poor immunotherapy response in colorectal cancer patients. However, the distinctions in the immune microenvironment between primary tumors and liver metastases are poorly characteriz

Externí odkaz: https://doaj.org/article/8ed76419e5ec4330855c5f6962cd2575

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Akademický článek

Per‐unit transformation for the combined analysis of multi‐energy integration

Autor: Zhang Zhang, Fei Wang, Hui Fan

Publikováno v: IET Renewable Power Generation, Vol 18, Iss 16, Pp 3890-3902 (2024)

Abstract To handle numerical issues caused by dimensional differences among heterogeneous states in integrated energy systems (IES), this paper proposes a novel per‐unit transformation method and explores its applications to the partial differentia

Externí odkaz: https://doaj.org/article/75a6469655b14e21b96249fa622e1a1e

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Akademický článek

Biomarkers and potential therapeutic targets driving progression of non-alcoholic steatohepatitis to hepatocellular carcinoma predicted through transcriptomic analysis

Autor: Hui Fan, Rong Wang, Bin Wen, Jing Xiong

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

BackgroundNon-alcoholic steatohepatitis (NASH) is the most prevalent chronic liver condition globally, with potential progression to cirrhosis, and even hepatocellular carcinoma (HCC). The increasing prevalence of NASH underscores the urgent need for

Externí odkaz: https://doaj.org/article/50bbf93961f04ac3a12e216f5031b9bb

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Akademický článek

Leukocyte Platelet‐Rich Plasma‐Derived Exosomes Restrained Macrophages Viability and Induced Apoptosis, NO Generation, and M1 Polarization

Autor: Xiong Li, Feifei Guo, Jiehua Deng, Jiasong Li, Jie Zhang, Ming Fu, Hui Fan

Publikováno v: Immunity, Inflammation and Disease, Vol 12, Iss 11, Pp n/a-n/a (2024)

ABSTRACT Background Chronic refractory wounds refer to wounds that cannot be repaired timely. Platelet‐rich plasma (PRP) has significant potential in chronic wound healing therapy. The exosomes isolated from PRP were proved to exhibit more effectiv

Externí odkaz: https://doaj.org/article/bb03aa2010c04f7a99ed36a5f91c31ae

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