Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses

Autor: Nj, Machado, Ap, Simões, Hb, Silva, Ap, Ardais, Mp, Kaster, Garção P, Di, Rodrigues, Pochmann D, Ai, Santos, Im, Araújo, Lo, Porciúncula, Âr, Tomé, Köfalvi A, Jm, Vaugeois, Agostinho P, El Yacoubi M, Ra, Cunha, Catarina Gomes

Publikováno v: CIÊNCIAVITAE
Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3929f281a89c76027ab45c6d4bd4a518
http://europepmc.org/abstract/med/26860412

The striatum drives the ergogenic effects of caffeine.

Autor: de Bem Alves AC; LABIOEX-Laboratory of Exercise Biology, Federal University of Santa Catarina-UFSC, Ararangua, SC, 88905-120, Brazil., Speck AE; LABIOEX-Laboratory of Exercise Biology, Federal University of Santa Catarina-UFSC, Ararangua, SC, 88905-120, Brazil., Farias HR; Post-graduation Program in Biological Sciences, Department of Biochemistry, Institute of Basic Sciences of Health, Federal University of Rio Grande do Sul-UFRGS, Porto Alegre, RS, 90040-060, Brazil., Martins LM; Post-graduation Program in Biological Sciences, Department of Physiology, Institute of Basic Sciences of Health, Federal University of Rio Grande do Sul-UFRGS, Porto Alegre, RS, 90050-170, Brazil., Dos Santos NS; LABIOEX-Laboratory of Exercise Biology, Federal University of Santa Catarina-UFSC, Ararangua, SC, 88905-120, Brazil., Pannata G; LABIOEX-Laboratory of Exercise Biology, Federal University of Santa Catarina-UFSC, Ararangua, SC, 88905-120, Brazil., Tavares AP; LABIOEX-Laboratory of Exercise Biology, Federal University of Santa Catarina-UFSC, Ararangua, SC, 88905-120, Brazil., de Oliveira J; Post-graduation Program in Biological Sciences, Department of Biochemistry, Institute of Basic Sciences of Health, Federal University of Rio Grande do Sul-UFRGS, Porto Alegre, RS, 90040-060, Brazil., Tomé ÂR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504, Coimbra, Portugal., Cunha RA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504, Coimbra, Portugal.; FMUC - Faculty of Medicine, University of Coimbra, 3004-504, Coimbra, Portugal., Aguiar AS Jr; LABIOEX-Laboratory of Exercise Biology, Federal University of Santa Catarina-UFSC, Ararangua, SC, 88905-120, Brazil. aderbal.aguiar@ufsc.br.

Publikováno v: Purinergic signalling [Purinergic Signal] 2023 Dec; Vol. 19 (4), pp. 673-683. Date of Electronic Publication: 2023 Jan 26.

Downregulation of Sirtuin 1 Does Not Account for the Impaired Long-Term Potentiation in the Prefrontal Cortex of Female APPswe/PS1dE9 Mice Modelling Alzheimer's Disease.

Autor: Lopes CR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Silva JS; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Santos J; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Rodrigues MS; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Madeira D; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Oliveira A; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Moreira-de-Sá A; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Lourenço VS; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Gonçalves FQ; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Silva HB; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Simões AP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Rolo AP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3004-531 Coimbra, Portugal., Canas PM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Tomé ÂR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3004-531 Coimbra, Portugal., Palmeira CM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3004-531 Coimbra, Portugal., Lopes JP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Cunha RA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal., Agostinho P; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal., Ferreira SG; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 09; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 09.

Effects of Chronic Caffeine Consumption on Synaptic Function, Metabolism and Adenosine Modulation in Different Brain Areas.

Autor: Lopes CR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Oliveira A; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Gaspar I; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Rodrigues MS; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Santos J; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Szabó E; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Silva HB; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Tomé ÂR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3000-456 Coimbra, Portugal., Canas PM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Agostinho P; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal., Carvalho RA; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3000-456 Coimbra, Portugal., Cunha RA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal., Simões AP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Lopes JP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Ferreira SG; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.

Publikováno v: Biomolecules [Biomolecules] 2023 Jan 04; Vol. 13 (1). Date of Electronic Publication: 2023 Jan 04.

Increased ATP release and CD73-mediated adenosine A 2A receptor activation mediate convulsion-associated neuronal damage and hippocampal dysfunction.

Autor: Augusto E; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Portugal; Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA., Gonçalves FQ; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Portugal., Real JE; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Portugal., Silva HB; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Portugal., Pochmann D; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Portugal., Silva TS; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Portugal., Matos M; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Portugal; Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA., Gonçalves N; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Portugal., Tomé ÂR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Portugal; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, Portugal., Chen JF; Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA; Molecular Neuropharmacology Lab, School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China., Canas PM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Portugal., Cunha RA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Portugal. Electronic address: cunharod@gmail.com.

Publikováno v: Neurobiology of disease [Neurobiol Dis] 2021 Sep; Vol. 157, pp. 105441. Date of Electronic Publication: 2021 Jul 03.