Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Álvaro Acosta-Serrano"'
Autor:
Isabel Saldanha, Rachel Lea, Oliver Manangwa, Gala Garrod, Lee R Haines, Álvaro Acosta-Serrano, Harriet Auty, Martha Betson, Jennifer S Lord, Liam J Morrison, Furaha Mramba, Stephen J Torr, Lucas J Cunningham
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 8, p e0012095 (2024)
BackgroundTsetse flies (Glossina sp.) are vectors of Trypanosoma brucei subspecies that cause human African trypanosomiasis (HAT). Capturing and screening tsetse is critical for HAT surveillance. Classically, tsetse have been microscopically analysed
Externí odkaz:
https://doaj.org/article/46acc7e2a5e14373885b306f1a4e1439
Autor:
Aitor Casas-Sanchez, Raghavendran Ramaswamy, Samïrah Perally, Lee R Haines, Clair Rose, Marcela Aguilera-Flores, Susana Portillo, Margot Verbeelen, Shahid Hussain, Laura Smithson, Cristina Yunta, Michael J Lehane, Sue Vaughan, Jan van den Abbeele, Igor C Almeida, Martin J Boulanger, Álvaro Acosta-Serrano
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011269 (2023)
Trypanosoma brucei spp. develop into mammalian-infectious metacyclic trypomastigotes inside tsetse salivary glands. Besides acquiring a variant surface glycoprotein (VSG) coat, little is known about the metacyclic expression of invariant surface anti
Externí odkaz:
https://doaj.org/article/4840a5e653f74072a772d97bda64b218
Autor:
Alba L. Montoya, Victoria M. Austin, Susana Portillo, Irodiel Vinales, Roger A. Ashmus, Igor Estevao, Sohan R. Jankuru, Yasser Alraey, Waleed S. Al-Salem, Álvaro Acosta-Serrano, Igor C. Almeida, Katja Michael
Publikováno v:
JACS Au, Vol 1, Iss 8, Pp 1275-1287 (2021)
Externí odkaz:
https://doaj.org/article/843c25e9b1764fc690a171137409d8c8
Autor:
Caroline E. Dewar, Aitor Casas-Sanchez, Constentin Dieme, Aline Crouzols, Lee R. Haines, Álvaro Acosta-Serrano, Brice Rotureau, Achim Schnaufer
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT The single-celled parasite Trypanosoma brucei is transmitted by hematophagous tsetse flies. Life cycle progression from mammalian bloodstream form to tsetse midgut form and, subsequently, infective salivary gland form depends on complex deve
Externí odkaz:
https://doaj.org/article/b31523e0c3274e81b45f168cc5ce1867
Autor:
Aitor Casas-Sanchez, Alessandra Romero-Ramirez, Eleanor Hargreaves, Cameron C. Ellis, Brian I. Grajeda, Igor L. Estevao, Edward I. Patterson, Grant L. Hughes, Igor C. Almeida, Tobias Zech, Álvaro Acosta-Serrano
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) extensively N-glycosylates its spike proteins, which are necessary for host cell invasion and the target of both vaccines and immunotherapies. These N-glycans are predicted to modu
Externí odkaz:
https://doaj.org/article/04fc6f6e723147be8da5ec9f6b4c53f9
Autor:
Waleed S. Al-Salem, Carla Solórzano, Gareth D. Weedall, Naomi A. Dyer, Louise Kelly-Hope, Aitor Casas-Sánchez, Yasser Alraey, Essam J. Alyamani, Alice Halliday, Salah M. Balghonaim, Khalid S. Alsohibany, Zeyad Alzeyadi, Mohamed H. Alzahrani, Ali M. Al-Shahrani, Abdullah M. Assiri, Ziad Memish, Álvaro Acosta-Serrano
Publikováno v:
Parasites & Vectors, Vol 12, Iss 1, Pp 1-9 (2019)
Abstract Background In the Kingdom of Saudi Arabia (KSA), Leishmania major and L. tropica are the main causative agents of Old World cutaneous leishmaniasis (CL). The national CL treatment regimen consists of topical 1% clotrimazole/2% fusidic acid c
Externí odkaz:
https://doaj.org/article/149dd6f8348640dca75889ef68ddcbb4
Autor:
Radoslaw P Kozak, Karina Mondragon-Shem, Christopher Williams, Clair Rose, Samirah Perally, Guy Caljon, Jan Van Den Abbeele, Katherine Wongtrakul-Kish, Richard A Gardner, Daniel Spencer, Michael J Lehane, Álvaro Acosta-Serrano
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009071 (2021)
African sleeping sickness is caused by Trypanosoma brucei, a parasite transmitted by the bite of a tsetse fly. Trypanosome infection induces a severe transcriptional downregulation of tsetse genes encoding for salivary proteins, which reduces its ant
Externí odkaz:
https://doaj.org/article/480054e28b21411f9d3a04c5a6f10ac0
Autor:
Marcos Sterkel, Lee R Haines, Aitor Casas-Sánchez, Vincent Owino Adung'a, Raquel J Vionette-Amaral, Shannon Quek, Clair Rose, Mariana Silva Dos Santos, Natalia García Escude, Hanafy M Ismail, Mark I Paine, Seth M Barribeau, Simon Wagstaff, James I MacRae, Daniel Masiga, Laith Yakob, Pedro L Oliveira, Álvaro Acosta-Serrano
Publikováno v:
PLoS Biology, Vol 19, Iss 1, p e3000796 (2021)
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides
Externí odkaz:
https://doaj.org/article/4f646e0fe7e142288bad18715c704987
Autor:
Freddie Bailey, Karina Mondragon-Shem, Lee Rafuse Haines, Amina Olabi, Ahmed Alorfi, José Antonio Ruiz-Postigo, Jorge Alvar, Peter Hotez, Emily R Adams, Iván D Vélez, Waleed Al-Salem, Julian Eaton, Álvaro Acosta-Serrano, David H Molyneux
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007092 (2019)
BACKGROUND:Major depressive disorder (MDD) associated with chronic neglected tropical diseases (NTDs) has been identified as a significant and overlooked contributor to overall disease burden. Cutaneous leishmaniasis (CL) is one of the most prevalent
Externí odkaz:
https://doaj.org/article/95774b70efc34d4f82e231f59ba19356
Autor:
Freddie Bailey, Karina Mondragon-Shem, Peter Hotez, José Antonio Ruiz-Postigo, Waleed Al-Salem, Álvaro Acosta-Serrano, David H Molyneux
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 8, p e0005739 (2017)
Externí odkaz:
https://doaj.org/article/5752ef24e3fb462f8eb23e6c330edc98