Zobrazeno 1 - 10
of 192
pro vyhledávání: '"A, Zukiwski"'
Autor:
Bonneterre, Jacques, Bosq, Jacques, Jamme, Philippe, Valent, Alexander, Gilles, Erard M., Zukiwski, Alexander A., Fuqua, Suzanne A.W., Lange, Carol A., O'Shaughnessy, Joyce
Publikováno v:
In ESMO Open 2016 1(4)
Autor:
Bonneterre, Jacques, Hutt, Emilie, Bosq, Jacques, Graham, J. Dinny, Powell, Matthew A., Leblanc, Eric, Fujiwara, Keiichi, Herzog, Thomas J., Coleman, Robert L., Clarke, Christine L., Gilles, Erard M., Zukiwski, Alexander A., Monk, Bradley J.
Publikováno v:
In Gynecologic Oncology September 2015 138(3):663-667
Autor:
Paul H Cottu, Jacques Bonneterre, Andrea Varga, Mario Campone, Alexandra Leary, Anne Floquet, Dominique Berton-Rigaud, Marie-Paule Sablin, Anne Lesoin, Keyvan Rezai, François M Lokiec, Catherine Lhomme, Jacques Bosq, Alice S Bexon, Erard M Gilles, Stefan Proniuk, Veronique Dieras, David M Jackson, Alexander Zukiwski, Antoine Italiano
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204973 (2018)
INTRODUCTION:Onapristone is a type I progesterone receptor (PR) antagonist, which prevents PR- mediated DNA transcription. Onapristone is active in multiple preclinical models and two prior studies demonstrated promising activity in patients with bre
Externí odkaz:
https://doaj.org/article/02cc52265fd94e9ab36980e19f1d5162
Akademický článek
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Autor:
Robert J. Mayer, Emily Valentino, Alexander Zukiwski, Michele Ly, Allison F. O'Neill, David Markowitz, G. Leonard, Peter T. Kingham, Ghassan K. Abou-Alfa, Alan P. Venook, Cameron Brennan, Olca Basturk, Emir Hoti, James J. Harding, Adam C. Yopp, Michael P. LaQuaglia, John D. Gordan, Muhammad Shaalan Beg, Stephen Leong, Mikaela Bradley, Ken Ren, John Crown, Rachel Kobos
Publikováno v:
Oncologist
Lessons Learned The fibrolamellar carcinoma-associated DNAJB1-PRKACA gene fusion transcript RNA codes for the catalytic domain of protein kinase A and, thus, overexpression of Aurora kinase A. ENMD-2076 showed a favorable toxicity profile. The limite
Akademický článek
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Autor:
Adrian Oo, Alexander Zukiwski, Keivan Zandi, Stefan Proniuk, Amin Jokar, Sazaly Abu Bakar, Pouya Hassandarvish
Publikováno v:
Journal of Antimicrobial Chemotherapy. 72:2438-2442
Objectives With no clinically effective antiviral options available, infections and fatalities associated with dengue virus (DENV) have reached an alarming level worldwide. We have designed this study to evaluate the efficacy of the celecoxib derivat
Autor:
Susanne M. Arnold, Tina Runk, Elise Brownell, Robert Cavaliere, Volker W. Stieber, Alex Zukiwski, Jeffrey Raizer, Stefan Proniuk, Randy L. Jensen, Priya Kumthekar, James Vredenburgh, Craig Devoe, Jai Grewal
Publikováno v:
Neuro Oncol
BACKGROUND AR-67 (formerly DB-67) is a novel 3rd generation camptothecin with improved safety and lipophilicity than current drugs in this class. Safety and efficacy of AR-67 were evaluated in a Phase 2 study in recurrent GBM/gliosarcoma in adult pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8724bbc7d4be0f38e6409080e59057f9
https://europepmc.org/articles/PMC6847938/
https://europepmc.org/articles/PMC6847938/
Autor:
Sarah R. Tritsch, Elsa B. Damonte, Laurence Booth, Stefan Proniuk, Cybele C. García, Javier González-Gallego, María J. Tuñón, Abraham Jacob, Claudia Soledad Sepúlveda, Federico Giovannoni, Heath Ecroyd, Jane L. Roberts, Paul Dent, St. Patrick Reid, Alexander Zukiwski, Sina Bavari
Publikováno v:
Journal of Cellular Physiology. 231:2286-2302
We have recently demonstrated that AR-12 (OSU-03012) reduces the function and ATPase activities of multiple HSP90 and HSP70 family chaperones. Combined knock down of chaperones or AR-12 treatment acted to reduce the expression of virus receptors and
Autor:
Véronique Diéras, Marie-Paule Sablin, Erard M. Gilles, Alice Bexon, Alexander Zukiwski, Mario Campone, Andrea Varga, Catherine Lhommé, Paul Cottu, Anne Floquet, Antoine Italiano, Dominique Berton-Rigaud, Stefan Proniuk, Anne Lesoin, Jacques Bosq, François Lokiec, Keyvan Rezai, David M. Jackson, Jacques Bonneterre, Alexandra Leary
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204973 (2018)
PLoS ONE
PLoS ONE
Introduction Onapristone is a type I progesterone receptor (PR) antagonist, which prevents PR- mediated DNA transcription. Onapristone is active in multiple preclinical models and two prior studies demonstrated promising activity in patients with bre