MINCLE and TLR9 agonists synergize to induce Th1/Th17 vaccine memory and mucosal recall in mice and non-human primates

Autor: Joshua S. Woodworth, Vanessa Contreras, Dennis Christensen, Thibaut Naninck, Nidhal Kahlaoui, Anne-Sophie Gallouët, Sébastien Langlois, Emma Burban, Candie Joly, Wesley Gros, Nathalie Dereuddre-Bosquet, Julie Morin, Ming Liu Olsen, Ida Rosenkrands, Ann-Kathrin Stein, Grith Krøyer Wood, Frank Follmann, Thomas Lindenstrøm, Tu Hu, Roger Le Grand, Gabriel Kristian Pedersen, Rasmus Mortensen

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Abstract Development of new vaccines tailored for difficult-to-target diseases is hampered by a lack of diverse adjuvants for human use, and none of the currently available adjuvants induce Th17 cells. Here, we develop a liposomal adjuvant, CAF®10b,

Externí odkaz: https://doaj.org/article/247707a325064a6ea6e1237d4d196721

SPOTLIGHT : Creating Pathways for Nontraditional Graduate Students

Autor: Woodworth-Jefcoats, Phoebe, Jahnke, Mackenzie, Howell, Evan A., Kobayashi, Donald R., Miller, Chad, Nichols, Ryan, Onuma, Megan

Publikováno v: Oceanography, 2023 Dec 01. 36(4), 68-69.

Externí odkaz: https://www.jstor.org/stable/27278256

Long-term changes in the ocean tide at Port Louis, Falkland Islands

Autor: P. L. Woodworth

Publikováno v: Ocean Science, Vol 20, Pp 887-894 (2024)

The historic tide gauge measurements at Port Louis in the Falkland Islands made by James Clark Ross in 1842 have been used to see whether there have been long-term changes in the ocean tide at that location. The conclusion is that there is no evidenc

Externí odkaz: https://doaj.org/article/5b84f32a44ab42b5828ac19dc1da9363

Feedstock variability impacts the bioconversion of sugar and lignin streams derived from corn stover by Clostridium tyrobutyricum and engineered Pseudomonas putida

Autor: Ilona A. Ruhl, Robert S. Nelson, Rui Katahira, Jacob S. Kruger, Xiaowen Chen, Stefan J. Haugen, Morgan A. Ingraham, Sean P. Woodworth, Hannah Alt, Kelsey J. Ramirez, Darren J. Peterson, Ling Ding, Philip D. Laible, Jeffrey G. Linger, Davinia Salvachúa

Publikováno v: Microbial Biotechnology, Vol 17, Iss 9, Pp n/a-n/a (2024)

Abstract Feedstock variability represents a challenge in lignocellulosic biorefineries, as it can influence both lignocellulose deconstruction and microbial conversion processes for biofuels and biochemicals production. The impact of feedstock variab

Externí odkaz: https://doaj.org/article/840651adb5c6409d98d4d4e05daf4c77

The impact of low-mode symmetry on inertial fusion energy output in the burning plasma state

Autor: J. E. Ralph, J. S. Ross, A. B. Zylstra, A. L. Kritcher, H. F. Robey, C. V. Young, O. A. Hurricane, A. Pak, D. A. Callahan, K. L. Baker, D. T. Casey, T. Döppner, L. Divol, M. Hohenberger, S. Le Pape, P. K. Patel, R. Tommasini, S. J. Ali, P. A. Amendt, L. J. Atherton, B. Bachmann, D. Bailey, L. R. Benedetti, L. Berzak Hopkins, R. Betti, S. D. Bhandarkar, J. Biener, R. M. Bionta, N. W. Birge, E. J. Bond, D. K. Bradley, T. Braun, T. M. Briggs, M. W. Bruhn, P. M. Celliers, B. Chang, T. Chapman, H. Chen, C. Choate, A. R. Christopherson, D. S. Clark, J. W. Crippen, E. L. Dewald, T. R. Dittrich, M. J. Edwards, W. A. Farmer, J. E. Field, D. Fittinghoff, J. Frenje, J. Gaffney, M. Gatu Johnson, S. H. Glenzer, G. P. Grim, S. Haan, K. D. Hahn, G. N. Hall, B. A. Hammel, J. Harte, E. Hartouni, J. E. Heebner, V. J. Hernandez, H. W. Herrmann, M. C. Herrmann, D. E. Hinkel, D. D. Ho, J. P. Holder, W. W. Hsing, H. Huang, K. D. Humbird, N. Izumi, L. C. Jarrott, J. Jeet, O. Jones, G. D. Kerbel, S. M. Kerr, S. F. Khan, J. Kilkenny, Y. Kim, H. Geppert-Kleinrath, V. Geppert-Kleinrath, C. Kong, J. M. Koning, J. J. Kroll, M. K. G. Kruse, B. Kustowski, O. L. Landen, S. Langer, D. Larson, N. C. Lemos, J. D. Lindl, T. Ma, M. J. MacDonald, B. J. MacGowan, A. J. Mackinnon, S. A. MacLaren, A. G. MacPhee, M. M. Marinak, D. A. Mariscal, E. V. Marley, L. Masse, K. D. Meaney, N. B. Meezan, P. A. Michel, M. Millot, J. L. Milovich, J. D. Moody, A. S. Moore, J. W. Morton, T. J. Murphy, K. Newman, J.-M. G. Di Nicola, A. Nikroo, R. Nora, M. V. Patel, L. J. Pelz, J. L. Peterson, Y. Ping, B. B. Pollock, M. Ratledge, N. G. Rice, H. G. Rinderknecht, M. Rosen, M. S. Rubery, J. D. Salmonson, J. Sater, S. Schiaffino, D. J. Schlossberg, M. B. Schneider, C. R. Schroeder, H. A. Scott, S. M. Sepke, K. Sequoia, M. W. Sherlock, S. Shin, V. A. Smalyuk, B. K. Spears, P. T. Springer, M. Stadermann, S. Stoupin, D. J. Strozzi, L. J. Suter, C. A. Thomas, R. P. J. Town, C. Trosseille, E. R. Tubman, P. L. Volegov, C. R. Weber, K. Widmann, C. Wild, C. H. Wilde, B. M. Van Wonterghem, D. T. Woods, B. N. Woodworth, M. Yamaguchi, S. T. Yang, G. B. Zimmerman

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)

Abstract Indirect Drive Inertial Confinement Fusion Experiments on the National Ignition Facility (NIF) have achieved a burning plasma state with neutron yields exceeding 170 kJ, roughly 3 times the prior record and a necessary stage for igniting pla

Externí odkaz: https://doaj.org/article/269b30b0fbbf4e519e1e759f9f698844