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Akademický článek

The predictive role of PD-L1 expression and CD8 + TIL levels in determining the neoadjuvant chemotherapy response in advanced ovarian cancer

Autor: T. Aliyeva, B. Y. Aktas, F. Gundogdu, E. Chalabiyev, Z. Arik, A. Usubutun

Publikováno v: Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-10 (2024)

Abstract Objective To analyze how the PD-L1 expression and CD8 + tumor infiltrating lymphocyte (TIL) levels in biopsy samples before neoadjuvant chemotherapy (NACT) can predict chemotherapy response score and survival for advanced high-grade serous o

Externí odkaz: https://doaj.org/article/cb0edd594830470db126313be3f9163e

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Akademický článek

A Low-Risk HPV-Associated Well-Differentiated Squamous Cell Carcinoma of the Cervix with Low-Grade Squamous Intraepithelial Lesion Morphology: Clinical and Pathologic Diagnostic Difficulties and Review of the Literature

Autor: Deniz ATES, Esra Nur SAHIN, Kübra KATIPOGLU, Alp USUBUTUN

Publikováno v: Türk Patoloji Dergisi, Vol 40, Iss 3, Pp 196-201 (2024)

Approximately 95% of cervical squamous cell carcinomas are associated with high-risk HPV, with a small number of HPV-independent tumors. However, low-risk HPV types have also been detected in rare cervical squamous cell carcinomas. Low-grade squamous

Externí odkaz: https://doaj.org/article/db0b0b93138d47aeabcc6c3c6a900630

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Akademický článek

Effect of hypoxia-inducible factor-1 alpha expression on survival in patients with metastatic cervical squamous cell carcinoma treated with first-line chemotherapy and bevacizumab

Autor: Hasan Cagri Yildirim, Hicran Anik, Deniz Ates Ozdemir, Rashad Ismayilov, Arif Akyildiz, Kerim Cayiroz, Fahri Ceyhan, Oguzalp Kavruk, Deniz Can Guven, Ozturk Ates, Alp Usubutun, Zafer Arik

Publikováno v: Biomolecules & Biomedicine (2024)

This study addresses the gap in understanding the prognostic relevance of hypoxia-inducible factor-1 alpha (HIF-1 alpha) expression in metastatic cervical squamous cell carcinoma (SCC) patients undergoing anti-vascular endothelial growth factor-based

Externí odkaz: https://doaj.org/article/0a6679b01dca4c8a82ddcef55b98579d

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Akademický článek

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Akademický článek

Evidence for Diverse Prognosis in High-Grade Serous Ovarian Carcinoma: Solid, Pseudoendometrioid, and Transitional-Like; So-Called 'SET Morphology' and Progesterone Receptor Status

Autor: Halit UNER, Metin DEMIR, Dincer GOKSULUK, Ayse KARS, Meral UNER, Alp USUBUTUN

Publikováno v: Türk Patoloji Dergisi, Vol 38, Iss 3, Pp 240-250 (2022)

Objective: High-grade serous ovarian carcinoma (HGSC) is one of the major tumors of the gynecological system with a poor survival rate and variable microscopic appearance. It was suggested that SET (solid, pseudo-endometrioid and transitional-like) m

Externí odkaz: https://doaj.org/article/63e2b9af87da4f30b45d1c3e946c55e5

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