Trypanosome spliced leader RNA for diagnosis of acoziborole treatment outcome in gambiense human African trypanosomiasis: A longitudinal follow-up study

Autor: Ngay Lukusa, Ipos, Van Reet, Nick, Mumba Ngoyi, Dieudonné, Mwamba Miaka, Erick, Masumu, Justin, Patient Pyana, Pati, Mutombo, Wilfried, Ngolo, Digas, Kobo, Vincent, Akwaso, Felix, Ilunga, Médard, Kaninda, Lewis, Mutanda, Sylvain, Mpoyi Muamba, Dieudonné, Valverde Mordt, Olaf, Tarral, Antoine, Rembry, Sandra, Büscher, Philippe, Lejon, Veerle

Publikováno v: In eBioMedicine December 2022 86

Trypanosome spliced leader RNA for diagnosis of acoziborole treatment outcome in gambiense human African trypanosomiasis: A longitudinal follow-up studyResearch in context

Autor: Ipos Ngay Lukusa, Nick Van Reet, Dieudonné Mumba Ngoyi, Erick Mwamba Miaka, Justin Masumu, Pati Patient Pyana, Wilfried Mutombo, Digas Ngolo, Vincent Kobo, Felix Akwaso, Médard Ilunga, Lewis Kaninda, Sylvain Mutanda, Dieudonné Mpoyi Muamba, Olaf Valverde Mordt, Antoine Tarral, Sandra Rembry, Philippe Büscher, Veerle Lejon

Publikováno v: EBioMedicine, Vol 86, Iss , Pp 104376- (2022)

Summary: Background: Detection of spliced leader (SL)-RNA allows sensitive diagnosis of gambiense human African trypanosomiasis (HAT). We investigated its diagnostic performance for treatment outcome assessment. Methods: Blood and cerebrospinal fluid

Externí odkaz: https://doaj.org/article/dd066076d06b4e58ab678a33a34d9502

Compliance with Early Long-Term Prophylaxis Guidelines for Severe Hemophilia A

Autor: Aouba, Achille ^∗, Harroche, Annie, Legrand, Faezeh ^∗, Rothschild, Chantal, Torchet, Marie-Françoise ^∗, d’Oiron, Roseline, Lambert, Thierry, Laurian, Yves ^∗, Rafowicz, Anne, Biernat, Jennifer, Goudemand, Jenny, Parquet, Armelle ^∗, Tintillier, Véronique, Wibaut, Bénédicte, Assollant, Anne Durin ^∗, Meunier, Sandrine, Négrier, Claude, Castet, Sabine, Guérin, Viviane ^∗, Huguenin, Yohann, Micheau, Marguerite ^∗, Ryman, Anne ^∗, Chambost, Hérve, Falaise, Céline, Claeyssens, Ségolène, Thiercelin-Legrand, Marie Françoise, Fiks-Sigaud, Marianne, Fouassier, Marc, Fressinaud, Edith ^∗, Trossaert, Marc, Voisin, Sophie, Faradji, Albert ^∗, Lutz, Patrick, Briquel, Marie Elisabeth ^∗, Frotscher, Birgit, Fimbel, Béatrice ^∗, Gruel, Yves, Guerois, Claude ^∗, Regina, Sandra ^∗, Valentin, Jean Baptiste, Biron Andreani, Christine, Codine, Philippe, Donadio, Daniel, Navarro, Robert, Rospide, Paola, Schved, Jean-François, Berger, Claire, Collet, Bénédicte, Derlon, Annie Borel, Gautier, Philippe, Bayart, Sophie, Guillet, Ben⊚ıt, Borg, JeanneYvonne, Dumesnil, Cécile, Normand, Charline ^∗, Schneider, Pascale, Tron, Philippe ^∗, Vannier, Jean-Pierre, Dutrillaux, Fabienne, Volot, Fabienne, Gembara, Piotr, Marques-Verdier, Alain, Adjaoud, Dalila, Barro, Claire, Pernod, Gilles ^∗, Polack, Ben⊚ıt, Pouzol, Patricia, Ounnoughene, Nadra, Paugy, Patricia ^∗, Robert, Valérie, Stieltjes, Natalie, Bastenaire, Brigitte, de Raucourt, Emmanuelle, Peynet, Jocelyne, Li-Thiao-Te, Valérie, Pautard, Brigitte ^∗, Behar, Catherine ^∗, Gorde, Stéphanie, Munzer, Martine, Gay, Valérie, Benz Lemoine, Elisabeth, Macchi, Laurent, De Lumley, Lionel ^∗, Gaillard, Solange ^∗, Oudot, Caroline, Deville, Anne, Monpoux, Fabrice, Bertrand, Marie Anne, Pan-Petesch, Brigitte, Hassoun, Abel, Coatmelec, Brigitte ^∗, Beurrier, Philippe ^∗, Damay, Michèle ^∗, Moreau, Philippe, Pouille-Lievin, Odile, Schoepfer, Caroline ^∗, Tarral, Eliane ^∗, Bianchin, Monique ^∗, Nguyen, Joël ^∗, Pincemaille, Olivier ^∗, Peter, Marie-Odile ^∗, Saultier, Paul, Guillaume, Yves, Demiguel, Virginie, Borel-Derlon, Annie, Vinciguerra, Christine, Boucekine, Mohamed, Baumstarck, Karine, Calvez, Thierry, Chambost, Hervé

Publikováno v: In The Journal of Pediatrics July 2021 234:212-219

Oral fexinidazole for stage 1 or early stage 2 African Trypanosoma brucei gambiense trypanosomiasis: a prospective, multicentre, open-label, cohort study

Autor: Victor Kande Betu Ku Mesu, DPH, Wilfried Mutombo Kalonji, MD, Clélia Bardonneau, MSc, Olaf Valverde Mordt, MSc, Digas Ngolo Tete, MPH, Séverine Blesson, MSc, François Simon, MSc, Sophie Delhomme, MSc, Sonja Bernhard, PhD, Hélène Mahenzi Mbembo, MD, Christian Mpia Moke, MD, Steven Lumeya Vuvu, MMed, Junior Mudji E'kitiak, MD, Felix Akwaso Masa, MD, Melchias Mukendi Ilunga, MD, Dieudonné Mpoyi Muamba Nzambi, MD, Tim Mayala Malu, MD, Serge Kapongo Tshilumbwa, MD, Franck Botalema Bolengi, MD, Mathieu Nkieri Matsho, MD, Crispin Lumbala, MPH, Bruno Scherrer, PhD, Nathalie Strub-Wourgaft, MD, Antoine Tarral, MD

Publikováno v: The Lancet Global Health, Vol 9, Iss 7, Pp e999-e1008 (2021)

Summary: Background: Staging and treatment of human African trypanosomiasis caused by Trypanosoma brucei gambiense (g-HAT) required lumbar puncture to assess cerebrospinal fluid (CSF) and intravenous drugs that cross the blood–brain barrier for lat

Externí odkaz: https://doaj.org/article/fc53e144d24e4957ad24602246c04574

Oral fexinidazole for late-stage African Trypanosoma brucei gambiense trypanosomiasis: a pivotal multicentre, randomised, non-inferiority trial

Autor: Mesu, Victor Kande Betu Ku, Kalonji, Wilfried Mutombo, Bardonneau, Clélia, Mordt, Olaf Valverde, Blesson, Séverine, Simon, François, Delhomme, Sophie, Bernhard, Sonja, Kuziena, Willy, Lubaki, Jean-Pierre Fina, Vuvu, Steven Lumeya, Ngima, Pathou Nganzobo, Mbembo, Hélène Mahenzi, Ilunga, Médard, Bonama, Augustin Kasongo, Heradi, Josué Amici, Solomo, Jean Louis Lumaliza, Mandula, Guylain, Badibabi, Lewis Kaninda, Dama, Francis Regongbenga, Lukula, Papy Kavunga, Tete, Digas Ngolo, Lumbala, Crispin, Scherrer, Bruno, Strub-Wourgaft, Nathalie, Tarral, Antoine

Publikováno v: In The Lancet 13-19 January 2018 391(10116):144-154