Bedaquiline-pretomanid-moxifloxacin-pyrazinamide for drug-sensitive and drug-resistant pulmonary tuberculosis treatment: a phase 2c, open-label, multicentre, partially randomised controlled trial

Autor: Bruinenberg, Paul, Beumont, Maria, Nedelman, Jerry, Li, Mengchun, Zuma-Gwala, Ntokozo, Rajaram, Shakira, Choo, Louise, Wills, Genevive, Betteridge, Matt, Leandra, Leandra, Olugbosi, Morounfolu, Borisov, Sergey, Cevik, Muge ^*, Thompson, Lindsay C, Upton, Caryn, Rolla, Valéria Cavalcanti, Malahleha, Mookho, Mmbaga, Blandina, Ngubane, Nosipho, Abu Bakar, Zamzurina, Rassool, Mohammed, Variava, Ebrahim, Dawson, Rodney, Staples, Suzanne, Lalloo, Umesh, Louw, Cheryl, Conradie, Francesca, Eristavi, Marika, Samoilova, Anastasia, Skornyakov, Sergey N, Ntinginya, Niyanda Elias, Haraka, Frederick, Praygod, George, Mayanja-Kizza, Harriett, Caoili, Janice, Balanag, Vincent, Dalcolmo, Margareth Pretti, McHugh, Timothy, Hunt, Robert, Solanki, Priya, Bateson, Anna, Crook, Angela M, Fabiane, Stella, Timm, Juliano, Sun, Eugene, Spigelman, Melvin, Sloan, Derek J, Gillespie, Stephen H

Publikováno v: In The Lancet Infectious Diseases September 2024 24(9):1003-1014

Treatment-Focused Rapid Genetic Testing in Breast Cancer

Autor: E. Novis, A. Spigelman, A.J. Chambers

Publikováno v: Breast, Vol 74, Iss , Pp 103646- (2024)

Externí odkaz: https://doaj.org/article/7284e75dbe9d47e9a2ee1b28b141b453

Short oral regimens for pulmonary rifampicin-resistant tuberculosis (TB-PRACTECAL): an open-label, randomised, controlled, phase 2B-3, multi-arm, multicentre, non-inferiority trial

Autor: Da Costa, Erin, Lachenal, Nathalie, James, Nicola, Sinha, Animesh, LeBeau, Kristen, Douch, Emma, Jolivert, Pascal, Poulsom, Hannah, Conijn, Marion, King, Sean, Spencer, Hannah, Cunden, Emma, Batts, Charlotte, Vuong, Thuy, Dietrich, Sebastian, McRae, Melissa, Wong, Sidney, Sun, Eugene, Olugbosi, Morounfolu, Shanks, Leslie, Hughes, Michael, Nahid, Payam, Kumwenda, Johnstone, Lorenz, Todd, Majumdar, Suman, Horsburgh, Robert C., Nuermberger, Eric, Meintjes, Graeme, Eisenach, Kathleen, Lienhardt, Christian, Nunn, Andrew, Lange, Christoph, Park, Laura, Gatts, Charlotte, Warren, Dominic, Kleiman, Robert, Mokua Nyangweso, George, Ochieng, Michael, Egondi, Thaddaeus, Onyango, Kevin, Omollo, Truphoso, Omollo, Raymond, Sturgess, Jo, Saunders, Steven, Allen, Elizabeth, Gajewski, Suzanne, Butoescu, Valentina, Hanekova, Jarmila, Etter, Coralie, Kambarov, Yerkbulan, Mphele, Siza, Sukhinina, Victoria, Huzar, Olesya, Reshetnikov, Andrey, Cilliè, Christine, Ahmed, Nada, Hunt, Robert, Merle, Corinne, Gulayim, Allanazarova, Mbenga, Mansa, Baltasheva, Zlikha Saparbaevna, Abdrasuliev, Tleubergen, Margaryan, Hasmik, Urgenishbaevna, Utemuratova Gozzal, Skrahina, Alena, Yatskevich, Natalia, Viatushka, Dzmitry, Apanasevich, Tatsiana, Skrahin, Aliaksandr, Duckworth, Lynette, Narasimooloo, Cindy, Lesego, Ndlovu Ellah, Motlhako, Sharon, Mashamaite, Mamomoko Ephenia, Mojapelo, Evelyn, Nyang'wa, Bern-Thomas ^*, Berry, Catherine, Kazounis, Emil, Motta, Ilaria, Parpieva, Nargiza, Tigay, Zinaida, Moodliar, Ronelle, Dodd, Matthew, Solodovnikova, Varvara, Liverko, Irina, Rajaram, Shakira, Rassool, Mohammed, McHugh, Timothy, Spigelman, Melvin, Moore, David A, Ritmeijer, Koert, du Cros, Philipp, Fielding, Katherine

Publikováno v: In The Lancet Respiratory Medicine February 2024 12(2):117-128

A tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome

Autor: Romy Walker, Khalid Mahmood, Jihoon E. Joo, Mark Clendenning, Peter Georgeson, Julia Como, Sharelle Joseland, Susan G. Preston, Yoland Antill, Rachel Austin, Alex Boussioutas, Michelle Bowman, Jo Burke, Ainsley Campbell, Simin Daneshvar, Emma Edwards, Margaret Gleeson, Annabel Goodwin, Marion T. Harris, Alex Henderson, Megan Higgins, John L. Hopper, Ryan A. Hutchinson, Emilia Ip, Joanne Isbister, Kais Kasem, Helen Marfan, Di Milnes, Annabelle Ng, Cassandra Nichols, Shona O’Connell, Nicholas Pachter, Bernard J. Pope, Nicola Poplawski, Abiramy Ragunathan, Courtney Smyth, Allan Spigelman, Kirsty Storey, Rachel Susman, Jessica A. Taylor, Linda Warwick, Mathilda Wilding, Rachel Williams, Aung K. Win, Michael D. Walsh, Finlay A. Macrae, Mark A. Jenkins, Christophe Rosty, Ingrid M. Winship, Daniel D. Buchanan, for the Family Cancer Clinics of Australia

Publikováno v: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)

Abstract Routine screening of tumors for DNA mismatch repair (MMR) deficiency (dMMR) in colorectal (CRC), endometrial (EC) and sebaceous skin (SST) tumors leads to a significant proportion of unresolved cases classified as suspected Lynch syndrome (S

Externí odkaz: https://doaj.org/article/0b22829c0e7441adb30b2047fa688507

Chronic intermittent ethanol exposure disrupts stress-related tripartite communication to impact affect-related behavioral selection in male rats

Autor: Munier, J.J., Shen, S., Rahal, D., Hanna, A., Marty, V.N., O'Neill, P.R., Fanselow, M.S., Spigelman, I.

Publikováno v: In Neurobiology of Stress May 2023 24