Výsledky vyhledávání

Akademický článek

Gut microbiota wellbeing index predicts overall health in a cohort of 1000 infants

Autor: Brandon Hickman, Anne Salonen, Alise J. Ponsero, Roosa Jokela, Kaija-Leena Kolho, Willem M. de Vos, Katri Korpela

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Abstract The human gut microbiota is central in regulating all facets of host physiology, and in early life it is thought to influence the host’s immune system and metabolism, affecting long-term health. However, longitudinally monitored cohorts wi

Externí odkaz: https://doaj.org/article/3bacf662c565486f8192020aa2f78c1e

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Akademický článek

Fecal microbiota transplantation influences microbiota without connection to symptom relief in irritable bowel syndrome patients

Autor: Anna K. Hartikainen, Jonna Jalanka, Perttu Lahtinen, Alise J. Ponsero, Tuomas Mertsalmi, Laura Finnegan, Fiona Crispie, Paul D. Cotter, Perttu Arkkila, Reetta Satokari

Publikováno v: npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-10 (2024)

Abstract Imbalanced microbiota may contribute to the pathophysiology of irritable bowel syndrome (IBS), thus fecal microbiota transplantation (FMT) has been suggested as a potential treatment. Previous studies on the relationship between clinical imp

Externí odkaz: https://doaj.org/article/7368523d417b497a98d3ab71a346798c

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Akademický článek

A cohort study in family triads: impact of gut microbiota composition and early life exposures on intestinal resistome during the first two years of life

Autor: Roosa Jokela, Katariina MM Pärnänen, Alise J Ponsero, Leo Lahti, Kaija-Leena Kolho, Willem M de Vos, Anne Salonen

Publikováno v: Gut Microbes, Vol 16, Iss 1 (2024)

Antibiotic resistance genes (ARGs) are prevalent in the infant gut microbiota and make up the intestinal resistome, representing a community ARG reservoir. This study focuses on the dynamics and persistence of ARGs in the early gut microbiota, and th

Externí odkaz: https://doaj.org/article/94b1063b776347419029f79ea249026d

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Akademický článek

Human milk oligosaccharide composition is affected by season and parity and associates with infant gut microbiota in a birth mode dependent manner in a Finnish birth cohortResearch in context

Autor: Dollwin Matharu, Alise J. Ponsero, Marton Lengyel, Agnes Meszaros-Matwiejuk, Kaija-Leena Kolho, Willem M. de Vos, Dora Molnar-Gabor, Anne Salonen

Publikováno v: EBioMedicine, Vol 104, Iss , Pp 105182- (2024)

Summary: Background: Human milk oligosaccharides (HMOs), their determinants, infant gut microbiota and health are under extensive research; however, seldom jointly addressed. Leveraging data from the HELMi birth cohort, we investigated them collectiv

Externí odkaz: https://doaj.org/article/7207f96d44c9485ea6746449e9ffb694

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