Zobrazeno 1 - 10
of 236
pro vyhledávání: '"A, Lepletier"'
Autor:
Vanessa Meier-Stephenson, Michael T. Hawkes, Catherine Burton, Ainslie Calcutt, Chris Davis, Jessica Dooley, Michael Good, Michael Houghton, Eloise Keeffe, Kelly Kim, Ailin Lepletier, Conar O’Neil, Ijeoma Ogbuehi, Victoria Ozberk, Manisha Pandey, Simone Reynolds, Avi Seth, William Stokes, Alena Tse-Chang, Ben Tyrrell, D. Lorne Tyrrell, Gregory J. Tyrrell, Maryna Yaskina
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Group A streptococci (Strep A) orStreptococcus pyogenes is a major human pathogen causing an estimated 500,000 deaths worldwide each year. Disease can range from mild pharyngitis to more severe infections, such as necrotizing fasc
Externí odkaz:
https://doaj.org/article/3b507af6859c43d3b742a62462d6dfde
Publikováno v:
Data in Brief, Vol 56, Iss , Pp 110786- (2024)
Mucosal-associated invariant T (MAIT) cells represent a unique unconventional T cell population important in eliciting immunomodulatory responses in a range of diseases, including infectious diseases, autoimmunity and cancer. This innate-like T cell
Externí odkaz:
https://doaj.org/article/85aa6affd00e46bcae20680cfbafbc7b
Autor:
Harshi Weerakoon, Ahmed Mohamed, Yide Wong, Jinjin Chen, Bhagya Senadheera, Oscar Haigh, Thomas S. Watkins, Stephen Kazakoff, Pamela Mukhopadhyay, Jason Mulvenna, John J. Miles, Michelle M. Hill, Ailin Lepletier
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Engagement of the T cell receptor (TCR) triggers molecular reprogramming leading to the acquisition of specialized effector functions by CD4 helper and CD8 cytotoxic T cells. While transcription factors, chemokines, and cytokines are known d
Externí odkaz:
https://doaj.org/article/6c5f2dbb912e4bc28c94d62032105a3d
Autor:
Victoria Ozberk, Mehfuz Zaman, Ailin Lepletier, Sharareh Eskandari, Jacqualine Kaden, Jamie-Lee Mills, Ainslie Calcutt, Jessica Dooley, Yongbao Huo, Emma L. Langshaw, Glen C. Ulett, Michael R. Batzloff, Michael F. Good, Manisha Pandey
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Mucosally active subunit vaccines are an unmet clinical need due to lack of licensed immunostimulants suitable for vaccine antigens. Here, we show that intranasal administration of liposomes incorporating: the Streptococcus pyogenes peptide
Externí odkaz:
https://doaj.org/article/6a7065b93c674ba3bb43501a205f2afc
Autor:
Jamie-Lee Mills, Ailin Lepletier, Victoria Ozberk, Jessica Dooley, Jacqualine Kaden, Ainslie Calcutt, Yongbao Huo, Allan Hicks, Ali Zaid, Michael F. Good, Manisha Pandey
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionStreptococcus pyogenes is a Gram-positive pathogen that causes a significant global burden of skin pyoderma and pharyngitis. In some cases, infection can lead to severe invasive streptococcal diseases. Previous studies have shown that IL-
Externí odkaz:
https://doaj.org/article/fd3c1d30a5e645bf9534f9da2df33d4a
Akademický článek
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Autor:
Simone Reynolds, Rukshan Ahamed Mohamed Rafeek, Adam Hamlin, Ailin Lepletier, Manisha Pandey, Natkunam Ketheesan, Michael F. Good
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract We have developed a candidate vaccine to protect against multiple strains of Streptococcus pyogenes infections. The candidate vaccine contains two synthetic peptides derived from S. pyogenes proteins: the M-protein epitope, p*17 and the IL-8
Externí odkaz:
https://doaj.org/article/0306dd7ec4e845928dcb77cf5b8d90f3
Autor:
Wilson Savino, Ailin Lepletier
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The thymus gland is a central lymphoid organ in which developing T cell precursors, known as thymocytes, undergo differentiation into distinct type of mature T cells, ultimately migrating to the periphery where they exert specialized effector functio
Externí odkaz:
https://doaj.org/article/f62156f051d442f3a13655e6015c4977
Autor:
Braun, Matthias, Aguilera, Amelia Roman, Sundarrajan, Ashmitha, Corvino, Dillon, Stannard, Kimberley, Krumeich, Sophie, Das, Indrajit, Lima, Luize G., Meza Guzman, Lizeth G., Li, Kunlun, Li, Rui, Salim, Nazhifah, Jorge, Maria Villancanas, Ham, Sunyoung, Kelly, Gabrielle, Vari, Frank, Lepletier, Ailin, Raghavendra, Ashwini, Pearson, Sally, Madore, Jason, Jacquelin, Sebastien, Effern, Maike, Quine, Brodie, Koufariotis, Lambros T., Casey, Mika, Nakamura, Kyohei, Seo, Eun Y., Hölzel, Michael, Geyer, Matthias, Kristiansen, Glen, Taheri, Touraj, Ahern, Elizabeth, Hughes, Brett G.M., Wilmott, James S., Long, Georgina V., Scolyer, Richard A., Batstone, Martin D., Landsberg, Jennifer, Dietrich, Dimo, Pop, Oltin T., Flatz, Lukas, Dougall, William C., Veillette, André, Nicholson, Sandra E., Möller, Andreas, Johnston, Robert J., Martinet, Ludovic, Smyth, Mark J., Bald, Tobias
Publikováno v:
In Immunity 13 October 2020 53(4):805-823
Akademický článek
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