Zobrazeno 1 - 10
of 1 779
pro vyhledávání: '"A, Grisoni"'
Autor:
Özçelik, Rıza, Grisoni, Francesca
Deep learning has significantly accelerated drug discovery, with 'chemical language' processing (CLP) emerging as a prominent approach. CLP learns from molecular string representations (e.g., Simplified Molecular Input Line Entry Systems [SMILES] and
Externí odkaz:
http://arxiv.org/abs/2407.12152
Publikováno v:
AJ, 167, 291. 2024
We present the first fluorine measurements in 12 normal giants belonging to the Galactic thin and thick disks using spectra obtained with the Phoenix infrared spectrometer on the 2.1m telescope at Kitt Peak. Abundances are determined from the (1-0) R
Externí odkaz:
http://arxiv.org/abs/2406.02855
Autor:
Grisoni, V., Chiappini, C., Miglio, A., Brogaard, K., Casali, G., Willett, E., Montalbán, J., Stokholm, A., Thomsen, J. S., Tailo, M., Matteuzzi, M., Valentini, M., Elsworth, Y., Mosser, B.
The origin of apparently young $\alpha$-rich stars in the Galaxy is still a matter of debate in Galactic archaeology, whether they are genuinely young or might be products of binary evolution and merger/mass accretion. We aim to shed light on the nat
Externí odkaz:
http://arxiv.org/abs/2312.07091
Autor:
Brogaard, K., Arentoft, T., Miglio, A., Casali, G., Thomsen, J. S., Tailo, M., Montalbán, J., Grisoni, V., Willett, E., Stokholm, A., Grundahl, F., Stello, D., Sandquist, E. L.
Publikováno v:
A&A 679, A23 (2023)
Asteroseismology of solar-like oscillations in giant stars allow the derivation of their masses and radii. For members of open clusters this allows an age estimate of the cluster which should be identical to the age estimate from the colour-magnitude
Externí odkaz:
http://arxiv.org/abs/2308.12731
Autor:
Willett, Emma, Miglio, Andrea, Mackereth, J. Ted, Chiappini, Cristina, Lyttle, Alexander J., Elsworth, Yvonne, Mosser, Benoît, Khan, Saniya, Anders, Friedrich, Casali, Giada, Grisoni, Valeria
The radial metallicity distribution of the Milky Way's disc is an important observational constraint for models of the formation and evolution of our Galaxy. It informs our understanding of the chemical enrichment of the Galactic disc and the dynamic
Externí odkaz:
http://arxiv.org/abs/2307.14422
Autor:
Casali, G., Grisoni, V., Miglio, A., Chiappini, C., Matteuzzi, M., Magrini, L., Willett, E., Cescutti, G., Matteucci, F., Stokholm, A., Tailo, M., Montalban, J., Elsworth, Y., Mosser, B.
Publikováno v:
A&A 677, A60 (2023)
Abundances of s-capture process elements in stars with exquisite asteroseismic, spectroscopic, and astrometric constraints offer a novel opportunity to study stellar evolution, nucleosynthesis, and Galactic chemical evolution. We aim to investigate o
Externí odkaz:
http://arxiv.org/abs/2305.06396
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Generative deep learning is reshaping drug design. Chemical language models (CLMs) – which generate molecules in the form of molecular strings – bear particular promise for this endeavor. Here, we introduce a recent deep learning archite
Externí odkaz:
https://doaj.org/article/630eaf3e629843169be4bb6b06ae861f
Artificial intelligence (AI) in the form of deep learning bears promise for drug discovery and chemical biology, $\textit{e.g.}$, to predict protein structure and molecular bioactivity, plan organic synthesis, and design molecules $\textit{de novo}$.
Externí odkaz:
http://arxiv.org/abs/2212.13295
Autor:
Lisa Stagi, Ilenia Bocchi, Daniela Bernardini, Marika Ciappa, Stefania Dellon, Gian Nicola Castiglione, Silvia Romano, Eros Fabrizi, Amanda Mattavelli, Ilaria Grisoni, Gabriella Finizia, Stefano Bonato
Publikováno v:
Therapeutic Advances in Drug Safety, Vol 15 (2024)
Background: Pharmacovigilance (PV) is the science and activities relating to the detection, assessment, understanding, and prevention of adverse effects or any other medicine/vaccine-related problem. Since its inception in the 1960s, PV has undergone
Externí odkaz:
https://doaj.org/article/b7e7e73c96824054b53e9102f21e7e4d
Autor:
Davide Boldini, Davide Ballabio, Viviana Consonni, Roberto Todeschini, Francesca Grisoni, Stephan A. Sieber
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Natural products are a diverse class of compounds with promising biological properties, such as high potency and excellent selectivity. However, they have different structural motifs than typical drug-like compounds, e.g., a wider range of m
Externí odkaz:
https://doaj.org/article/46f966aabfba49c5aca910c8dd8a61cc