Zobrazeno 1 - 10
of 2 122
pro vyhledávání: '"A, De Flora"'
Autor:
Andrea Benzi, Markus Heine, Sonia Spinelli, Annalisa Salis, Anna Worthmann, Björn Diercks, Cecilia Astigiano, Raúl Pérez Mato, Adela Memushaj, Laura Sturla, Valerio Vellone, Gianluca Damonte, Michelle Y. Jaeckstein, Friedrich Koch-Nolte, Hans-Willi Mittrücker, Andreas H. Guse, Antonio De Flora, Joerg Heeren, Santina Bruzzone
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2024)
IntroductionDuring thermogenesis, adipose tissue (AT) becomes more active and enhances oxidative metabolism. The promotion of this process in white AT (WAT) is called “browning” and, together with the brown AT (BAT) activation, is considered as a
Externí odkaz:
https://doaj.org/article/6cbc007a0f474be38c4530fd56e6e433
Autor:
Abbotto, Elena, Miro, Caterina, Piacente, Francesco, Salis, Annalisa, Murolo, Melania, Nappi, Annarita, Millo, Enrico, Russo, Eleonora, Cichero, Elena, Sturla, Laura, Del Rio, Alberto, De Flora, Antonio, Nencioni, Alessio, Dentice, Monica, Bruzzone, Santina
Publikováno v:
In Biomedicine & Pharmacotherapy October 2023 166
Autor:
Elena Abbotto, Caterina Miro, Francesco Piacente, Annalisa Salis, Melania Murolo, Annarita Nappi, Enrico Millo, Eleonora Russo, Elena Cichero, Laura Sturla, Alberto Del Rio, Antonio De Flora, Alessio Nencioni, Monica Dentice, Santina Bruzzone
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115326- (2023)
Sirtuin 6 (SIRT6) has a critical role in cutaneous Squamous Cell Carcinoma (cSCC): SIRT6 silencing in skin SCC cells has pro-differentiating effects and SIRT6 deletion abrogated DMBA-TPA-induced skin tumorigenesis in mice. On the other hand, SIRT6 ac
Externí odkaz:
https://doaj.org/article/487ea97481c846938c17d04b08a92400
Autor:
Cecilia Astigiano, Francesco Piacente, Maria Elena Laugieri, Andrea Benzi, Christian A. Di Buduo, Carolina P. Miguel, Debora Soncini, Michele Cea, Antonella Antonelli, Mauro Magnani, Alessandra Balduini, Antonio De Flora, Santina Bruzzone
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6759 (2023)
Sirtuin 6 (SIRT6) is a member of the mammalian NAD+-dependent deac(et)ylase sirtuin family. SIRT6’s anti-inflammatory roles are emerging increasingly often in different diseases and cell types, including endothelial cells. In this study, the role o
Externí odkaz:
https://doaj.org/article/9aea6083f9c84c3b9c7ccede3d20014f
Autor:
Campo, Neus, De Flora, Cecilia, Maffettone, Roberta, Manoli, Kyriakos, Sarathy, Siva, Santoro, Domenico, Gonzalez-Olmos, Rafael, Auset, Maria
Publikováno v:
In Water Research 1 February 2020 169
Autor:
Pamela Becherini, Debora Soncini, Silvia Ravera, Elisa Gelli, Claudia Martinuzzi, Giulia Giorgetti, Antonia Cagnetta, Fabio Guolo, Federico Ivaldi, Maurizio Miglino, Sara Aquino, Katia Todoerti, Antonino Neri, Andrea Benzi, Mario Passalacqua, Alessio Nencioni, Ida Perrotta, Maria Eugenia Gallo Cantafio, Nicola Amodio, Antonio De Flora, Santina Bruzzone, Roberto M. Lemoli, Michele Cea
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 494 (2023)
Cancer cells fuel growth and energy demands by increasing their NAD+ biosynthesis dependency, which therefore represents an exploitable vulnerability for anti-cancer strategies. CD38 is a NAD+-degrading enzyme that has become crucial for anti-MM ther
Externí odkaz:
https://doaj.org/article/0e796c050e73475a981a9b6091ebf662
Role of Liver CD38 in the Regulation of Metabolic Pathways during Cold-Induced Thermogenesis in Mice
Autor:
Andrea Benzi, Sonia Spinelli, Laura Sturla, Markus Heine, Alexander W. Fischer, Friedrich Koch-Nolte, Hans-Willi Mittrücker, Andreas H. Guse, Antonio De Flora, Joerg Heeren, Santina Bruzzone
Publikováno v:
Cells, Vol 11, Iss 23, p 3812 (2022)
Boosting NAD+ levels are considered a promising means to promote healthy aging and ameliorate dysfunctional metabolism. The expression of CD38, the major NAD+-consuming enzyme, is downregulated during thermogenesis in both brown and white adipose tis
Externí odkaz:
https://doaj.org/article/2bbe202a521248858605b5a7300a8e0b
Autor:
Sebastiano La Maestra, Silvano Garibaldi, Roumen Balansky, Francesco D’Agostini, Rosanna T. Micale, Silvio De Flora
Publikováno v:
Cells, Vol 11, Iss 20, p 3313 (2022)
The binding of SARS-CoV-2 spikes to the cell receptor angiotensin-converting enzyme 2 (ACE2) is a crucial target both in the prevention and in the therapy of COVID-19. We explored the involvement of oxidoreductive mechanisms by investigating the effe
Externí odkaz:
https://doaj.org/article/536514fb0b834cbb8804248d288e7582
Autor:
Maria Francesconi, Marta Giovanetti, Lucia De Florio, Marta Fogolari, Roberta Veralli, Cecilia De Flora, Silvia Spoto, Antonello Maruotti, Elisabetta Riva, Silvia Angeletti, Massimo Ciccozzi
Publikováno v:
Pathogens, Vol 11, Iss 9, p 1011 (2022)
Since 2020, the COVID-19 pandemic represented an important worldwide burden. Well-structured surveillance by reliable and timely genomic data collection is crucial. In this study, a genomic monitoring analysis of all SARS-CoV-2 positive samples retri
Externí odkaz:
https://doaj.org/article/21afa62d1a614e3499f8ebecb2a1310b
Autor:
Benzi, Andrea, Heine, Markus, Spinelli, Sonia, Salis, Annalisa, Worthmann, Anna, Diercks, Björn, Astigiano, Cecilia, Mato, Raúl Pérez, Memushaj, Adela, Sturla, Laura, Vellone, Valerio, Damonte, Gianluca, Jaeckstein, Michelle Y., Koch-Nolte, Friedrich, Mittrücker, Hans-Willi, Guse, Andreas H., De Flora, Antonio, Heeren, Joerg, Bruzzone, Santina
Publikováno v:
Frontiers in Endocrinology; 2024, p1-17, 17p