Zobrazeno 1 - 7
of 7
pro vyhledávání: '"82/103"'
Autor:
Yoann Saucereau, Tom H. Wilson, Matthew C. K. Tang, Martin C. Moncrieffe, Steven W. Hardwick, Dimitri Y. Chirgadze, Sandro G. Soares, Maria Jose Marcaida, Nick Gay, Monique Gangloff
Aedes aegypti can act as a vector for viral pathogens but the mechanism of viral resistance and evolving host-pathogen tolerance are poorly understood. Here the authors structurally characterise a duplicated pair of interacting Toll immunoreceptors a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65d6b47144d1c470df66fe7b6c819cb
https://www.repository.cam.ac.uk/handle/1810/341567
https://www.repository.cam.ac.uk/handle/1810/341567
Autor:
Guo, Jingxu, Liu, Bin, Thorikay, Midory, Yu, Minmin, Li, Xiaoyan, Tong, Zhen, Salmon, Richard M, Read, Randy, Ten Dijke, Peter, Morrell, Nicholas, Li, Wei
Publikováno v:
Nature Communications, 13(1). NATURE PORTFOLIO
Heterozygous mutations in BMPR2 (bone morphogenetic protein (BMP) receptor type II) cause pulmonary arterial hypertension. BMPRII is a receptor for over 15 BMP ligands, but why BMPR2 mutations cause lung-specific pathology is unknown. To elucidate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e809ad6dffa969517a8ecd4aaa304bb4
https://doi.org/10.1038/s41467-022-30111-2
https://doi.org/10.1038/s41467-022-30111-2
Autor:
J. Paul Luzio, Brett M. Collins, Nicholas A. Bright, Joel B. Dacks, James S. Swarbrick, Lena Wartosch, Harriet Crawley-Snowdon, Ji-Chun Yang, Luther J. Davis, Nathan R. Zaccai, Lauren P. Jackson, David J. Owen, Matthew N.J. Seaman, David Neuhaus, Emily K. Herman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Funder: Discovery Grants from the Natural Sciences and Engineering Research Council of Canada (RES0043758, RES0046091)
VARP and TBC1D5 are accessory/regulatory proteins of retromer-mediated retrograde trafficking from endosomes. Using an NMR/X-r
VARP and TBC1D5 are accessory/regulatory proteins of retromer-mediated retrograde trafficking from endosomes. Using an NMR/X-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35ae705b081e2551f54a714b8279d2c
http://link.springer.com/article/10.1038/s41467-020-18773-2
http://link.springer.com/article/10.1038/s41467-020-18773-2
Autor:
Lori Peacock, Olivia J. S. Macleod, Jean-Mathieu Bart, Sophie Ravel, Svenja Hester, Martin C. Taylor, Camilla Trevor, Ralph Minter, Jack D. Sunter, Tristan J. Vaughan, Wendy Gibson, Paula MacGregor, Steven Rust, Matthew K. Higgins, Shabaz Mohammed, Mark Carrington, Nicholas J. Savill
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Macleod, O J S, Bart, J M, MacGregor, P, Peacock, L, Savill, N J, Hester, S, Ravel, S, Sunter, J D, Trevor, C, Rust, S, Vaughan, T J, Minter, R, Mohammed, S, Gibson, W, Taylor, M C, Higgins, M K & Carrington, M 2020, ' A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies ', Nature Communications, vol. 11, no. 1, 1326 . https://doi.org/10.1038/s41467-020-15125-y
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11, art. 1326 [12 p.]. ⟨10.1038/s41467-020-15125-y⟩
Macleod, O J S, Bart, J-M, Macgregor, P, Peacock, L, Hester, S, Ravel, S, Sunter, J D, Trevor, C, Rust, S, Vaughan, T J, Minter, R, Mohammed, S, Gibson, W, Taylor, M C, Higgins, M K & Carrington, M 2020, ' A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies ', Nature Communications, vol. 11, 1326 (2020) . https://doi.org/10.1038/s41467-020-15125-y
Macleod, O J S, Bart, J M, MacGregor, P, Peacock, L, Savill, N J, Hester, S, Ravel, S, Sunter, J D, Trevor, C, Rust, S, Vaughan, T J, Minter, R, Mohammed, S, Gibson, W, Taylor, M C, Higgins, M K & Carrington, M 2020, ' A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies ', Nature Communications, vol. 11, no. 1, 1326 . https://doi.org/10.1038/s41467-020-15125-y
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11, art. 1326 [12 p.]. ⟨10.1038/s41467-020-15125-y⟩
Macleod, O J S, Bart, J-M, Macgregor, P, Peacock, L, Hester, S, Ravel, S, Sunter, J D, Trevor, C, Rust, S, Vaughan, T J, Minter, R, Mohammed, S, Gibson, W, Taylor, M C, Higgins, M K & Carrington, M 2020, ' A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies ', Nature Communications, vol. 11, 1326 (2020) . https://doi.org/10.1038/s41467-020-15125-y
Persistent pathogens have evolved to avoid elimination by the mammalian immune system including mechanisms to evade complement. Infections with African trypanosomes can persist for years and cause human and animal disease throughout sub-Saharan Afric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d67987dc434dc81572261c646a5450
https://doaj.org/article/26bfcfd0e9cc483dae71e8f47f88e8ec
https://doaj.org/article/26bfcfd0e9cc483dae71e8f47f88e8ec
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Bone morphogenetic proteins (BMPs) are multifunctional cytokines of the transforming growth factor β (TGFβ) superfamily with potential therapeutic applications due to their broad biological functionality. Designing BMP mimetics with specific activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c0b829d0cbb66c3bb9a2c5300dde10
http://hdl.handle.net/10044/1/75049
http://hdl.handle.net/10044/1/75049
Autor:
Macleod, Olivia J. S., Bart, Jean-Mathieu, MacGregor, Paula, Peacock, Lori, Savill, Nicholas J., Hester, Svenja, Ravel, Sophie, Sunter, Jack D., Trevor, Camilla, Rust, Steven, Vaughan, Tristan J., Minter, Ralph, Mohammed, Shabaz, Gibson, Wendy, Taylor, Martin C., Higgins, Matthew K., Carrington, Mark
Persistent pathogens have evolved to avoid elimination by the mammalian immune system including mechanisms to evade complement. Infections with African trypanosomes can persist for years and cause human and animal disease throughout sub-Saharan Afric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e44227d3a33b3aeac2d6e72639e4c863
Bone morphogenetic proteins (BMPs) are multifunctional cytokines of the transforming growth factor β (TGFβ) superfamily with potential therapeutic applications due to their broad biological functionality. Designing BMP mimetics with specific activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5809f4c7b19c03da0d0ee70ca5ff920e