Zobrazeno 1 - 10
of 28
pro vyhledávání: '"7SK Small Nuclear RNA"'
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2006 Nov . 103(46), 17349-17354.
Externí odkaz:
https://www.jstor.org/stable/30052435
Autor:
David H. Price, Nicolas Buisine, Patricia Uguen, Duy Nguyen, Olivier Fayol, Annemieke A. Michels, Olivier Bensaude
Publikováno v:
BMC Molecular and Cell Biology, Vol 22, Iss 1, Pp 1-12 (2021)
BMC Molecular and Cell Biology
BMC Molecular and Cell Biology
Background The 7SK small nuclear RNA (snRNA) found in most metazoans is a key regulator of P-TEFb which in turn regulates RNA polymerase II elongation. Although its primary sequence varies in protostomes, its secondary structure and function are cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a102f8dcf67a2e249608d27a793df32
https://doi.org/10.1186/s12860-021-00381-7
https://doi.org/10.1186/s12860-021-00381-7
Autor:
Karl Brillet, Isabelle Lebars, Anne-Catherine Dock-Bregeon, Denise Martinez-Zapien, Eric Ennifar, Guillaume Bec
Publikováno v:
RNA
RNA, Cold Spring Harbor Laboratory Press, 2020, 26 (9), pp.1184-1197. ⟨10.1261/rna.074955.120⟩
RNA, Cold Spring Harbor Laboratory Press, 2020, 26 (9), pp.1184-1197. ⟨10.1261/rna.074955.120⟩
International audience; The 7SK small nuclear RNA (7SKsnRNA) plays a key role in the regulation of RNA polymerase II by sequestrating and inhibiting the positive transcription elongation factor b (P-TEFb) in the 7SK ribonucleoprotein complex (7SKsnRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839effc4331cc29a4e083a3f8242ec67
https://europepmc.org/articles/PMC7430674/
https://europepmc.org/articles/PMC7430674/
Publikováno v:
J Mol Biol
7SK small nuclear RNA (snRNA) is an abundant and ubiquitously expressed noncoding RNA that functions to modulate the activity of RNA Polymerase II (RNAPII) in part by stabilizing distinct pools of 7SK-protein complexes. Prevailing models suggest that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989aca1c22f5f8c1bd8bd3db038c19bc
https://pubmed.ncbi.nlm.nih.gov/33684393
https://pubmed.ncbi.nlm.nih.gov/33684393
Autor:
Nakul M. Shah, Blerta Xhemalce, Sravan K. Devanathan, Samantha B. Shelton, Nathan S. Abell, Marvin Mercado
Publikováno v:
Cell Reports, Vol 22, Iss 6, Pp 1374-1383 (2018)
Summary: RNAP II switching from the paused to the productive transcription elongation state is a pivotal regulatory step that requires specific phosphorylations catalyzed by the P-TEFb kinase. Nucleosolic P-TEFb activity is inhibited by its interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7857934c13fba205dd4596d78aaf2f
https://doi.org/10.1016/j.celrep.2018.01.028
https://doi.org/10.1016/j.celrep.2018.01.028
Publikováno v:
Transcription
Transcription, Taylor & Francis, 2018, 9 (2), pp.95-101. ⟨10.1080/21541264.2017.1344346⟩
Transcription, Taylor & Francis, 2018, 9 (2), pp.95-101. ⟨10.1080/21541264.2017.1344346⟩
The 7SK small nuclear RNA is a multifunctional transcriptional regulatory RNA that controls the nuclear activity of the positive transcription elongation factor b (P-TEFb), specifically targets P-TEFb to the promoter regions of selected protein-codin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2745a6fb04e84d39b2997d486e8c2b90
https://europepmc.org/articles/PMC5834218/
https://europepmc.org/articles/PMC5834218/
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2017, 36 (7), pp.934-948. ⟨10.15252/embj.201695740⟩
EMBO Journal, EMBO Press, 2017, 36 (7), pp.934-948. ⟨10.15252/embj.201695740⟩
The 7SK small nuclear RNP (snRNP), composed of the 7SK small nuclear RNA (snRNA), MePCE, and Larp7, regulates the mRNA elongation capacity of RNA polymerase II (RNAPII) through controlling the nuclear activity of positive transcription elongation fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ad7b3d2d97bdfe1bff3648a1260c42
https://hal.archives-ouvertes.fr/hal-03002510
https://hal.archives-ouvertes.fr/hal-03002510
Publikováno v:
Tumor Biology. 36:2809-2814
7SK small nuclear RNA (snRNA) is a 331-333-bp non-coding RNA, which recruits HEXIM 1/2 protein to inhibit positive elongation factor b (P-TEFb) activity. P-TEFb is an essential factor in alleviating promoter-proximal paused RNA polymerase II (Pol II)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94d5a9bc4472e5678fe40a85d5b9b49
https://doi.org/10.1007/s13277-014-2907-8
https://doi.org/10.1007/s13277-014-2907-8
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2013, 41 (8), pp.4686-4698. ⟨10.1093/nar/gkt159⟩
Nucleic Acids Research, Oxford University Press, 2013, 41 (8), pp.4686-4698. ⟨10.1093/nar/gkt159⟩
Through controlling the nuclear level of active positive transcription elongation factor b (P-TEFb), the 7SK small nuclear RNA (snRNA) functions as a key regulator of RNA polymerase II transcription. Together with hexamethylene bisacetamide-inducible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ba3fde4ba4bac316648605ee42e13d
https://doi.org/10.1093/nar/gkt159
https://doi.org/10.1093/nar/gkt159
Autor:
Anne-Catherine Dock-Bregeon, Sarah Bourbigot, Bruno Kieffer, Jérôme Coutant, Pascal Eberling, Isabelle Lebars
Publikováno v:
RNA
RNA, Cold Spring Harbor Laboratory Press, 2016, 22 (12), pp.1844-1858. ⟨10.1261/rna.056523.116⟩
RNA, Cold Spring Harbor Laboratory Press, 2016, 22 (12), pp.1844-1858. ⟨10.1261/rna.056523.116⟩
The small nuclear 7SK RNA regulates RNA polymerase II (RNA Pol II) transcription, by sequestering and inhibiting the positive transcription elongation factor b (P-TEFb). P-TEFb is stored in the 7SK ribonucleoprotein (RNP) that contains the three nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4107a9f05ca22b56c3de88e9aea02b
https://europepmc.org/articles/PMC5113205/
https://europepmc.org/articles/PMC5113205/