Zobrazeno 1 - 4
of 4
pro vyhledávání: '"631/92/96"'
Autor:
Shan Tang, Adam T. Beattie, Lucie Kafkova, Gianluca Petris, Nicolas Huguenin-Dezot, Marc Fiedler, Matthew Freeman, Jason W. Chin
Publikováno v:
Nature
Hydrolase enzymes, including proteases, are encoded by 2–3% of the genes in the human genome and 14% of these enzymes are active drug targets1. However, the activities and substrate specificities of many proteases—especially those embedded in mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb94aaefa718ed2175ff02656d11181c
https://doi.org/10.1038/s41586-022-04414-9
https://doi.org/10.1038/s41586-022-04414-9
Autor:
Shugo Sasaki, Julia Ast, Daniela Nasteska, Fiona B. Ashford, Andrea Bacon, Zania Stamataki, Tom Podewin, Alejandra Tomas, Nicholas H. F. Fine, David J. Hodson, Giuseppe D'Agostino, Maria Lucey, Elisa D’Este, Christopher A. Reissaus, Amelia K. Linnemann, Stefan Trapp, Zsombor Koszegi, Johannes Broichhagen, Ben Jones, Kai Johnsson, Daniel I. Brierley, Francis C. Lynn, Benoit Hastoy, Anastasia Arvaniti, Frank Reimann, Davide Calebiro
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Ast, J, Arvaniti, A, Fine, N H F, Nasteska, D, Ashford, F B, Stamataki, Z, Koszegi, Z, Bacon, A, Jones, B J, Lucey, M A, Sasaki, S, Brierley, D I, Hastoy, B, Tomas, A, D'Agostino, G, Reimann, F, Lynn, F C, Reissaus, C A, Linnemann, A K, D'Este, E, Calebiro, D, Trapp, S, Johnsson, K, Podewin, T, Broichhagen, J & Hodson, D J 2020, ' Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics ', Nature Communications, vol. 11, no. 1, 467, pp. 467 . https://doi.org/10.1038/s41467-020-14309-w
Nature Communications
Ast, J, Arvaniti, A, Fine, N H F, Nasteska, D, Ashford, F B, Stamataki, Z, Koszegi, Z, Bacon, A, Jones, B J, Lucey, M A, Sasaki, S, Brierley, D I, Hastoy, B, Tomas, A, D'Agostino, G, Reimann, F, Lynn, F C, Reissaus, C A, Linnemann, A K, D'Este, E, Calebiro, D, Trapp, S, Johnsson, K, Podewin, T, Broichhagen, J & Hodson, D J 2020, ' Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics ', Nature Communications, vol. 11, no. 1, 467, pp. 467 . https://doi.org/10.1038/s41467-020-14309-w
The glucagon-like peptide-1 receptor (GLP1R) is a class B G protein-coupled receptor (GPCR) involved in metabolism. Presently, its visualization is limited to genetic manipulation, antibody detection or the use of probes that stimulate receptor activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39bcef7b82d9b4f5c53076b4bcbaa9a
http://link.springer.com/article/10.1038/s41467-020-14309-w
http://link.springer.com/article/10.1038/s41467-020-14309-w
Autor:
Ast, Julia, Arvaniti, Anastasia, Fine, Nicholas H. F., Nasteska, Daniela, Ashford, Fiona B., Stamataki, Zania, Koszegi, Zsombor, Bacon, Andrea, Jones, Ben J., Lucey, Maria A., Sasaki, Shugo, Brierley, Daniel I., Hastoy, Benoit, Tomas, Alejandra, D’Agostino, Giuseppe, Reimann, Frank, Lynn, Francis C., Reissaus, Christopher A., Linnemann, Amelia K., D’Este, Elisa, Calebiro, Davide, Trapp, Stefan, Johnsson, Kai, Podewin, Tom, Broichhagen, Johannes, Hodson, David J.
Funder: U.S. Department of Health & Human Services | National Institutes of Health (NIH)
Funder: EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Fram
Funder: EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Fram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00cb6a8a6171b5bfd3b91a126c2a8e85
Autor:
Ast, Julia, Arvaniti, Anastasia, Fine, Nicholas H. F., Nasteska, Daniela, Ashford, Fiona B., Stamataki, Zania, Koszegi, Zsombor, Bacon, Andrea, Jones, Ben J., Lucey, Maria A., Sasaki, Shugo, Brierley, Daniel I., Hastoy, Benoit, Tomas, Alejandra, D’Agostino, Giuseppe, Reimann, Frank, Lynn, Francis C., Reissaus, Christopher A., Linnemann, Amelia K., D’Este, Elisa, Calebiro, Davide, Trapp, Stefan, Johnsson, Kai, Podewin, Tom, Broichhagen, Johannes, Hodson, David J.
Funder: U.S. Department of Health & Human Services | National Institutes of Health (NIH)
Funder: EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Fram
Funder: EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Fram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df711818d83db859225ab523a10a90e5