Emergence of methicillin resistance predates the clinical use of antibiotics

Autor: Jesper Larsen, Claire L. Raisen, Xiaoliang Ba, Nicholas J. Sadgrove, Guillermo F. Padilla-González, Monique S. J. Simmonds, Igor Loncaric, Heidrun Kerschner, Petra Apfalter, Rainer Hartl, Ariane Deplano, Stien Vandendriessche, Barbora Černá Bolfíková, Pavel Hulva, Maiken C. Arendrup, Rasmus K. Hare, Céline Barnadas, Marc Stegger, Raphael N. Sieber, Robert L. Skov, Andreas Petersen, Øystein Angen, Sophie L. Rasmussen, Carmen Espinosa-Gongora, Frank M. Aarestrup, Laura J. Lindholm, Suvi M. Nykäsenoja, Frederic Laurent, Karsten Becker, Birgit Walther, Corinna Kehrenberg, Christiane Cuny, Franziska Layer, Guido Werner, Wolfgang Witte, Ivonne Stamm, Paolo Moroni, Hannah J. Jørgensen, Hermínia de Lencastre, Emilia Cercenado, Fernando García-Garrote, Stefan Börjesson, Sara Hæggman, Vincent Perreten, Christopher J. Teale, Andrew S. Waller, Bruno Pichon, Martin D. Curran, Matthew J. Ellington, John J. Welch, Sharon J. Peacock, David J. Seilly, Fiona J. E. Morgan, Julian Parkhill, Nazreen F. Hadjirin, Jodi A. Lindsay, Matthew T. G. Holden, Giles F. Edwards, Geoffrey Foster, Gavin K. Paterson, Xavier Didelot, Mark A. Holmes, Ewan M. Harrison, Anders R. Larsen

Publikováno v: Larsen, Jesper; Raisen, Claire L; Ba, Xiaoliang; Sadgrove, Nicholas J; Padilla-González, Guillermo F; Simmonds, Monique S J; Loncaric, Igor; Kerschner, Heidrun; Apfalter, Petra; Hartl, Rainer; Deplano, Ariane; Vandendriessche, Stien; Černá Bolfíková, Barbora; Hulva, Pavel; Arendrup, Maiken C; Hare, Rasmus K; Barnadas, Céline; Stegger, Marc; Sieber, Raphael N; Skov, Robert L; ... (2022). Emergence of methicillin resistance predates the clinical use of antibiotics. Nature, 602(7895), pp. 135-141. Springer Nature Limited 10.1038/s41586-021-04265-w
Larsen, J, Raisen, C L, Sadgrove, N J, Padilla-González, G F, Simmonds, M S J, Loncaric, I, Kerschner, H, Apfalter, P, Hartl, R, Ariane Deplano, A, Vandendriessche, S, Bolfíková, B Č, Hulva, P, Arendrup, M C, Hare, R K, Barnadas, C, Stegger, M, Sieber, R N, Skov, R L, Petersen, A, Angen, Ø, Rasmussen, S L, Espinosa-Gongora, C, Aarestrup, F M, Lindholm, L, Nykäsenoja, S, Laurent, F, Becker, K, Walther, B, Kehrenberg, C, Cuny, C, Layer, F, Werner, G, Witte, W, Stamm, I, Moroni, P, Jørgensen, H, de Lencastre, H, Cercenado, E, García-Garrote, F, Börjesson, S, Hæggman, S, Perreten, V, J. Teale, C, Waller, A, Pichon, B, Curran, M, Ellington, M, Welch, J, Peacock, S, Seilly, D, Morgan, F, Parkhill, J, Hadjirin, N, Lindsay, J, Holden, M T G, Edwards, G F, Foster, G, Paterson, G, Didelot, X, Holmes, M, Harrison, E & Larsen, A R 2022, ' Emergence of methicillin resistance predates the clinical use of antibiotics ', Nature, vol. 602, no. 7895, pp. 135-141 . https://doi.org/10.1038/s41586-021-04265-w
Larsen, J, Raisen, C L, Ba, X, Sadgrove, N J, Padilla-González, G F, Simmonds, M S J, Loncaric, I, Kerschner, H, Apfalter, P, Hartl, R, Deplano, A, Vandendriessche, S, Černá Bolfíková, B, Hulva, P, Arendrup, M C, Hare, R K, Barnadas, C, Stegger, M, Sieber, R N, Skov, R L, Petersen, A, Angen, Ø, Rasmussen, S L, Espinosa-Gongora, C, Aarestrup, F M, Lindholm, L J, Nykäsenoja, S M, Laurent, F, Becker, K, Walther, B, Kehrenberg, C, Cuny, C, Layer, F, Werner, G, Witte, W, Stamm, I, Moroni, P, Jørgensen, H J, de Lencastre, H, Cercenado, E, García-Garrote, F, Börjesson, S, Hæggman, S, Perreten, V, Teale, C J, Waller, A S, Pichon, B, Curran, M D, Ellington, M J, Welch, J J, Peacock, S J, Seilly, D J, Morgan, F J E, Parkhill, J, Hadjirin, N F, Lindsay, J A, Holden, M T G, Edwards, G F, Foster, G, Paterson, G K, Didelot, X, Holmes, M A, Harrison, E M & Larsen, A R 2022, ' Emergence of methicillin resistance predates the clinical use of antibiotics ', Nature, vol. 602, pp. 135–141 . https://doi.org/10.1038/s41586-021-04265-w
Paterson, G K 2022, ' Emergence of methicillin resistance predates the clinical use of antibiotics ', Nature, vol. 602, pp. 135-141 . https://doi.org/10.1038/s41586-021-04265-w

X.D. was funded by a grant from the National Institute for Health Research (NIHR) Health Protection Research Unit in Genomics and Enabling Data (no. NIHR200892). M.A.H. was supported by grants from the Medical Research Council (nos. G1001787/1, MR/N0

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c43e8cd39a109234141bcbc266c126

Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae

Autor: Eva Heinz, Karthick Vasudevan, Thandavarayan Ramamurthy, Stephen Baker, Ankur Mutreja, Naresh Chand Sharma, Gordon Dougan, Agila Kumari Pragasam, Pradeep Haldar, Robert C. Will, Balaji Veeraraghavan, Bhabatosh Das, Lucky Sangal, Vyacheslav Melnikov, Vartul Sangal, Dhirendra Kumar

Publikováno v: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)

Diphtheria is a respiratory disease caused by the bacterium Corynebacterium diphtheriae. Although the development of a toxin-based vaccine in the 1930s has allowed a high level of control over the disease, cases have increased in recent years. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077151837071b325f7067782a4c9ec1b
https://archive.lstmed.ac.uk/17201/1/41467_2021_Article_21870.pdf

Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae

Autor: Will, Robert C., Ramamurthy, Thandavarayan, Sharma, Naresh Chand, Veeraraghavan, Balaji, Sangal, Lucky, Haldar, Pradeep, Pragasam, Agila Kumari, Vasudevan, Karthick, Kumar, Dhirendra, Das, Bhabatosh, Heinz, Eva, Melnikov, Vyacheslav, Baker, Stephen, Sangal, Vartul, Dougan, Gordon, Mutreja, Ankur

Funder: DH | National Institute for Health Research (NIHR); doi: https://doi.org/10.13039/501100000272
Funder: RCUK | Medical Research Council (MRC); doi: https://doi.org/10.13039/501100000265
Diphtheria is a respiratory disease caused by t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::092f3e27898c8fc4a5638021a832bbc0