Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

Autor: Shugo Sasaki, Julia Ast, Daniela Nasteska, Fiona B. Ashford, Andrea Bacon, Zania Stamataki, Tom Podewin, Alejandra Tomas, Nicholas H. F. Fine, David J. Hodson, Giuseppe D'Agostino, Maria Lucey, Elisa D’Este, Christopher A. Reissaus, Amelia K. Linnemann, Stefan Trapp, Zsombor Koszegi, Johannes Broichhagen, Ben Jones, Kai Johnsson, Daniel I. Brierley, Francis C. Lynn, Benoit Hastoy, Anastasia Arvaniti, Frank Reimann, Davide Calebiro

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Ast, J, Arvaniti, A, Fine, N H F, Nasteska, D, Ashford, F B, Stamataki, Z, Koszegi, Z, Bacon, A, Jones, B J, Lucey, M A, Sasaki, S, Brierley, D I, Hastoy, B, Tomas, A, D'Agostino, G, Reimann, F, Lynn, F C, Reissaus, C A, Linnemann, A K, D'Este, E, Calebiro, D, Trapp, S, Johnsson, K, Podewin, T, Broichhagen, J & Hodson, D J 2020, ' Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics ', Nature Communications, vol. 11, no. 1, 467, pp. 467 . https://doi.org/10.1038/s41467-020-14309-w

The glucagon-like peptide-1 receptor (GLP1R) is a class B G protein-coupled receptor (GPCR) involved in metabolism. Presently, its visualization is limited to genetic manipulation, antibody detection or the use of probes that stimulate receptor activ

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http://link.springer.com/article/10.1038/s41467-020-14309-w

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

Autor: Ast, Julia, Arvaniti, Anastasia, Fine, Nicholas H. F., Nasteska, Daniela, Ashford, Fiona B., Stamataki, Zania, Koszegi, Zsombor, Bacon, Andrea, Jones, Ben J., Lucey, Maria A., Sasaki, Shugo, Brierley, Daniel I., Hastoy, Benoit, Tomas, Alejandra, D’Agostino, Giuseppe, Reimann, Frank, Lynn, Francis C., Reissaus, Christopher A., Linnemann, Amelia K., D’Este, Elisa, Calebiro, Davide, Trapp, Stefan, Johnsson, Kai, Podewin, Tom, Broichhagen, Johannes, Hodson, David J.

Funder: U.S. Department of Health & Human Services | National Institutes of Health (NIH)
Funder: EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Fram

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df711818d83db859225ab523a10a90e5