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of 14
pro vyhledávání: '"615.10724"'
Autor:
Monastyrski, Daniel
Therapeutisches Drug Monitoring (TDM) von Meropenem auf Intensivstationen ist empfehlenswert, um den gewünschten therapeutischen Effekt zu erzielen und Über- oder Unterdosierungen und somit Resistenzentwicklung zu vermeiden. Problematisch für Klin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67e55e31e34e644726735bd36464deca
Autor:
Buck, Lauren Michelle Jenny
A variety of marketed drugs are known to cause damage to the hearing and/or balance systems in humans (ototoxicity). The absence of standard testing protocols to identify ototoxic effects at the pre-clinical stage is one major reason for the incidenc
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.570108
Autor:
Saxena, Kunal
Upon agonist binding the u-opioid receptor (MOPr) is phosphorylated and can recruit arrestin-2 (beta-arrestin-l) and arrestin-3 (p-arrestin-2). Apart from promoting the desensitization and intemalization of the MOPr, the binding of arrestins can also
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.559233
Autor:
O'Flynn, Neil
The use of the insect virus Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) as a gene delivery vector for mammalian cells began in 1995 with the discovery that mammalian hepatocytes could be efficiently infected by the virus (40). Si
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578081
Autor:
Maple, Hannah Jane
Screening for protein-ligand binding interactions is a key step during early stage drug discovery programmes. The fragment-based screening approach has gained popularity in recent years as a highly promising alternative to traditional high-throughput
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.559091
Autor:
Demco, Anthony A.
The discovery of drugs that can effectively treat disease and alleviate pain is one of the core challenges facing modern medicine. The tools and techniques of machine learning have perhaps the greatest potential to provide a fast and effcient route t
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500800
Autor:
Middleton, Danielle Fiona
Compared to 1-substituted-5-aminoimidazoles relatively few 1-substituted-5-hydroxyimidazoles have been reported; however, an interesting 1-substituted-5-hydroxyimidazole is the immunosuppressive agent bredinin, which shows antiviral, antimalarial, an
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490012
Autor:
Snowdon, Claire
Background: The ethical basis of randomised controlled trials is equipoise, whether at the collective or individual level. Neonatal intensive care trials are therefore conducted in a context of clinical uncertainty as well as stress and trauma. The t
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422316