Zobrazeno 1 - 10
of 27
pro vyhledávání: '"60107 Enzymes"'
Autor:
Nguyen, Tien
Submitted in total fulfillment of the requirements for the degree of Doctor of Philosophy to the School of Agriculture, Biomedicine and Environment, La Trobe University, Victoria, Australia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15006cf6b8dde9803dbe3c87e3fb366f
Autor:
SIKANYIKA, NKUMBU LUWI
Alzheimer���s is a disease caused by a toxic chemical build-up in the brain. My thesis investigates a new molecule that can increase the brain���s natural ability to break down this chemical build-up. In the end, I discovered 2 versions o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d54dd1ea2a71c863c111d3501eca42e
Autor:
Minervo Perez
The use of computational approaches to understand kinase substrate preference has been a powerful tool in the search to develop artificial peptide probes to monitor kinase activity, however, most of these efforts focus on a small portion of the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c53cbff5b358500142971a9b510184e
Autor:
Hewitt, Chad S
There are over 100 deubiquitinating enzymes (DUBs) that account for seven distinct DUB subfamilies, each having different functions and binding topology to ubiquitin. One of these subfamilies, the ubiquitin C-terminal hydrolases (UCHs), contain four
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1125629a966be7bb44cfe2f32ed8f595
Autor:
Purohit, Vatsal
HMG-CoA reductase from Pseudomonas mevalonii (PmHMGR) catalyzes the oxidation of mevalonate and mevaldyl-CoA to form HMG-CoA using CoA-SH and two NAD+ cofactors. While the enzyme has been used extensively as a drug target in humans to treat hyperchol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53def3cc0316fb04b5106c4ba84ea1fc
Autor:
LaCombe, Jonathan Mark
Indiana University-Purdue University Indianapolis (IUPUI)
Down syndrome (DS) is a complex genetic disorder caused by the triplication of human chromosome 21 (Hsa21). The presence of an extra copy of an entire chromosome greatly disrupts the copy
Down syndrome (DS) is a complex genetic disorder caused by the triplication of human chromosome 21 (Hsa21). The presence of an extra copy of an entire chromosome greatly disrupts the copy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bb50d312e68241ccb2940d6e4208fe
Autor:
Jan P. Kraus, Paula Giménez-Mascarell, Tomas Majtan, June Ereño-Orbea, Juraj Majtan, Jaroslav Klaudiny, Luis Alfonso Martínez-Cruz, Iker Oyenarte
Publikováno v:
Journal of Structural Biology. 202:82-93
Cystathionine β-synthase (CBS), the key enzyme in the transsulfuration pathway, links methionine metabolism to the biosynthesis of cellular redox controlling molecules. CBS catalyzes the pyridoxal-5'-phosphate-dependent condensation of serine and ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2f131dc388e786388b6ca2f73c7770
https://doi.org/10.1016/j.jsb.2017.12.008
https://doi.org/10.1016/j.jsb.2017.12.008
Autor:
Brundel, Daniel Han Sung
Nanoparticles are gaining interest as a tool to improve the delivery of anticancer drugs to tumours, while reducing side-effects at the same time. However, currently, only a small fraction of nanoparticles reaches the tumour, due to overexpression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcef63bfac167efed22ddc2cd006ea50
Autor:
Buckle, Ashley
Supporting Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e716d6814d8aeaeefd45394e5e4dca16
Autor:
Norvil, Allison B
DNA methylation is an epigenetic modification that is nearly ubiquitous. Eukaryotic DNA methylation contributes to the regulation of gene expression and maintaining genome integrity. In mammals, DNA methylation occurs primarily on the C5 carbon of cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f67cd8a45a922dcbe8286bf73710078