Zobrazeno 1 - 10
of 4 282
pro vyhledávání: '"6-OHDA"'
Autor:
Yesim Yeni, Sıdıka Genc, Muhammed Sait Ertugrul, Hayrunnisa Nadaroglu, Arzu Gezer, Ali Sefa Mendil, Ahmet Hacımuftuoglu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Parkinson’s disease (PD) is a chronic neurodegenerative case. As the disease progresses, the response time to doses of levodopa (L-Dopa) becomes shorter and the effects of the drug are severely limited by some undesirable side effects such
Externí odkaz:
https://doaj.org/article/31e06e2d52344af390a72f5dd28bd883
Autor:
Yong-Ren Chen, Chin-Chean Wong, Yi-No Chen, Bing-Heng Yang, Po-Hui Lee, Chia-Yang Shiau, Kuo-Chuan Wang, Chung-Hsing Li
Publikováno v:
Journal of Dental Sciences, Vol 19, Iss 4, Pp 2035-2044 (2024)
Background/purpose: Mesenchymal stem cells exhibit therapeutic efficacy for brain injury. This study examined the effect of mesenchymal stem cells derived from human exfoliated deciduous teeth (SHED) on alleviating symptoms of Parkinson's disease (PD
Externí odkaz:
https://doaj.org/article/422b98c97f514ddf8071a3746c81f24a
Autor:
Clémence Riffard, Laïla Letaïef, Safa Azar, Armanda Casrouge, Isabelle Brunet, Jean-Luc Teillaud, Marie-Caroline Dieu-Nosjean
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Tertiary lymphoid structures (TLS) are lymphoid organs present in inflammatory non-lymphoid tissues. Studies have linked TLS to favorable outcomes for patients with cancers or infectious diseases, but the mechanisms underlying their formatio
Externí odkaz:
https://doaj.org/article/c8dc9424248c4f60b04d4f05518a3b45
Autor:
Michele Barboza de Carvalho, Bruna Teixeira-Silva, Suelen Adriani Marques, Andrea Alice Silva, Marcelo Cossenza, Adriana da Cunha Faria-Melibeu, Claudio Alberto Serfaty, Paula Campello-Costa
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34120- (2024)
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by selective dopaminergic loss. Non dopaminergic neurotransmitters such as glutamate are also involved in PD progression. NMDA receptor/postsynaptic density protein 95
Externí odkaz:
https://doaj.org/article/d5e2f38c7baa46149bb91141d326692c
Autor:
Paula Izquierdo-Altarejos, Yaiza M. Arenas, Mar Martínez-García, Lola Vázquez, Gergana Mincheva, Magnus Doverskog, Thomas P. Blackburn, Nicolaas I. Bohnen, Marta Llansola, Vicente Felipo
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
BackgroundParkinson's disease (PD) affects more than 6 million people worldwide. Along with motor impairments, patients and animal models exhibiting PD symptoms also experience cognitive impairment, fatigue, anxiety, and depression. Currently, there
Externí odkaz:
https://doaj.org/article/04a2fabb9d7449218acd47c64c0b750b
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9545 (2024)
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor symptoms like tremors and bradykinesia. PD’s pathology involves the aggregation of α-synuclein and loss of dopaminergic neurons, leading to altered neural oscillatio
Externí odkaz:
https://doaj.org/article/62eab4f475e5472183605aff41c81c0e
Autor:
Amine Bourzam, Yosra Hamdi, Seyma Bahdoudi, Karthi Duraisamy, Mouna El Mehdi, Magali Basille-Dugay, Omayma Dlimi, Maher Kharrat, Anne Vejux, Gérard Lizard, Taoufik Ghrairi, Benjamin Lefranc, David Vaudry, Jean A. Boutin, Jérôme Leprince, Olfa Masmoudi-Kouki
Publikováno v:
Cells, Vol 13, Iss 14, p 1188 (2024)
Astrocytes specifically synthesize and release endozepines, a family of regulatory peptides including octadecaneuropeptide (ODN). We have previously reported that ODN rescues neurons and astrocytes from 6-OHDA-induced oxidative stress and cell death.
Externí odkaz:
https://doaj.org/article/c4fff4d4ea234ecb9224171425bc6f6e
Autor:
Váldina Solimar Lopes Cardoso, Anderson Valente-Amaral, Rayan Fidel Martins Monteiro, Clarina Loius Silva Meira, Natália Silva de Meira, Milton Nascimento da Silva, João de Jesus Viana Pinheiro, Gilmara de Nazareth Tavares Bastos, João Soares Felício, Elizabeth Sumi Yamada
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionParkinson’s disease affects 2% of the population aged over 65 years and is the second most common neurodegenerative disorder in the general population. The appearance of motor symptoms is associated with the degeneration of dopaminergic
Externí odkaz:
https://doaj.org/article/087989332568491384b399adaa521528