Zobrazeno 1 - 10 of 21 pro vyhledávání: '"6 hydroxydopamine lesion"'
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Comparison of voluntary and forced exercise effects on motor behavior in 6-hydroxydopamine-lesion rat model of Parkinson’s disease
Autor: Vahid Sheibani, Nasser Naghdi, Forouzan Rafie, Mehdi Shahbazi, Mahmoud Sheikh
Publikováno v: Sport Sciences for Health. 13:203-211
Parkinson’s disease (PD) is one of the most common neurodegenerative disorders. This study compared the effects of two types of exercises on motor dysfunction in characterizing adult male Wistar rats with unilateral 6-hydroxydopamine lesions placed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5518a0c77e5d532058fbcf0c76c1a28
https://doi.org/10.1007/s11332-017-0354-9
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3
Forelimb akinesia and metabolic alteration in the striatum following unilateral 6-hydroxydopamine lesion in rats: An in vivo proton magnetic resonance spectroscopy study
Autor: Bo Young Choe, K. S. Hong, Kyung Nam Ryu, C. B. Choi, H. S. Lee, Do-Wan Lee, Ji Seon Park, C. S. Yin, C. H. Lee, Su Young Kim
Publikováno v: Neurochemical Journal. 5:270-277
The 6-hydroxydopamine (6-OHDA) lesions of the nigrostriatal dopamine system in rat can develop neuropathological and neurochemcial changes similar to those seen in patients with Parkinson’s disease (PD). The purpose of this study was to test the hy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97ee6915d9be591e820592bfa6bc694c
https://doi.org/10.1134/s1819712411040088
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4
Increasing Extracellular Potassium Results in Subthalamic Neuron Activity Resembling That Seen in a 6-Hydroxydopamine Lesion
Autor: Ulrike Gimsa, Ulf Strauss, Arndt Rolfs, Riidiger Köhling, Jeannette Henning, Fu-Wen Zhou, Arne Battefeld, Andreas Wree, Reiner Benecke, Stefan Jean-Pierre Haas
Publikováno v: Journal of Neurophysiology. 99:2902-2915
Abnormal neuronal activity in the subthalamic nucleus (STN) plays a crucial role in the pathophysiology of Parkinson's disease (PD). Although altered extracellular potassium concentration ([K+]o) and sensitivity to [K+]o modulates neuronal activity,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b06cc8e43904fb349b1bcf42004e10d
https://doi.org/10.1152/jn.00402.2007
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5
Nigral 6-hydroxydopamine lesion impairs performance in a lateralised choice reaction time task--impact of training and task parameters
Autor: Hanna S. Lindgren, Alexander Klein, Stephen B. Dunnett
Publikováno v: Behavioural Brain Research; Vol 266
Unilateral intrastriatal and intra-medial forebrain bundle injections of 6-OHDA impair the performance in a lateralised choice reaction time task. However, the extent and pattern of deficits after nigral 6-OHDA injections is less well studied, as wel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b663d8db4a438dd6ca9b2f7b807137c
https://pubmed.ncbi.nlm.nih.gov/24613237
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6
Microtransplantation of dopaminergic cell suspensions: further characterization and optimization of grafting parameters
Autor: Almuth Brandis, Anna Papazoglou, Guido Nikkhah, Alexandra Roedter, Gero Falkenstein, Christoph Rosenthal
Publikováno v: Cell Transplantation, Vol 18 (2009)
Intracerebral transplantation of dopaminergic (DA) cells is currently further explored as a potential restorative therapy for Parkinson's disease (PD). However, before they can be considered for a more widespread clinical use a number of critical iss
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fd06851f51daa6dc04802aa52099af
https://pubmed.ncbi.nlm.nih.gov/19499701
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