Assessing Drug Sensitivity in Fission Yeast Using Half-Maximal Inhibitory Concentration (IC50) Assays.

Autor: Chhipa MA; Molecular Science Program, Yeates School of Graduate Studies, Toronto Metropolitan University, Toronto, ON, Canada., Sanayhie SA; Department of Chemistry and Biology, Yeates School of Graduate Studies, Toronto Metropolitan University, Toronto, ON, Canada., Sabatinos SA; Molecular Science Program, Yeates School of Graduate Studies, Toronto Metropolitan University, Toronto, ON, Canada. ssabatinos@torontomu.ca.; Department of Chemistry and Biology, Yeates School of Graduate Studies, Toronto Metropolitan University, Toronto, ON, Canada. ssabatinos@torontomu.ca.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2025; Vol. 2862, pp. 241-253.

Andrographolide induced cytotoxicity and cell cycle arrest in Giardia trophozoites.

Autor: Haldar T; Division of Parasitology, ICMR-National Institute of Cholera and Enteric Diseases (ICMR-NICED), India., Sardar SK; Division of Parasitology, ICMR-National Institute of Cholera and Enteric Diseases (ICMR-NICED), India., Ghosal A; Division of Parasitology, ICMR-National Institute of Cholera and Enteric Diseases (ICMR-NICED), India., Prasad A; Division of Parasitology, ICMR-National Institute of Cholera and Enteric Diseases (ICMR-NICED), India., Nakano YS; Department of Parasitology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8640, Japan., Dutta S; Division of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases (ICMR-NICED), Kolkata, India., Nozaki T; Department of Biomedical Chemistry, School of International Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Ganguly S; Division of Parasitology, ICMR-National Institute of Cholera and Enteric Diseases (ICMR-NICED), India. Electronic address: sandipanganguly@hotmail.com.

Publikováno v: Experimental parasitology [Exp Parasitol] 2024 Jul; Vol. 262, pp. 108773. Date of Electronic Publication: 2024 May 07.

Incomplete Plasmodium falciparum growth inhibition following piperaquine treatment translates into increased parasite viability in the in vitro parasite reduction ratio assay.

Autor: Walz A; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Sax S; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Scheurer C; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Tamasi B; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Mäser P; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Wittlin S; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland.

Publikováno v: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2024 Apr 30; Vol. 14, pp. 1396786. Date of Electronic Publication: 2024 Apr 30 (Print Publication: 2024).

Using the super-learner to predict the chemical acute toxicity on rats.

Autor: Li Y; School of Materials Science and Engineering, Beihang University, Beijing 100191, China., Wang B; School of Materials Science and Engineering, Beihang University, Beijing 100191, China., Ma F; State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China., Fan W; School of Materials Science and Engineering, Beihang University, Beijing 100191, China., Wang Y; School of Materials Science and Engineering, Beihang University, Beijing 100191, China., Chen L; School of Public Health, Southeast University, Nanjing, China., Dong Z; School of Materials Science and Engineering, Beihang University, Beijing 100191, China; School of Public Health, Southeast University, Nanjing, China. Electronic address: chaomi_87@163.com.

Publikováno v: Journal of hazardous materials [J Hazard Mater] 2024 Dec 05; Vol. 480, pp. 136311. Date of Electronic Publication: 2024 Oct 28.

The extended recovery ring-stage survival assay is a scalable alternative for artemisinin susceptibility phenotyping of fresh Plasmodium falciparum isolates.

Autor: Okitwi M; Infectious Diseases Research Collaboration, Kampala, Uganda., Shoue DA; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA., Checkley LA; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA., Orena S; Infectious Diseases Research Collaboration, Kampala, Uganda., Ceja FG; Dominican University of California, San Rafael, California, USA., Taremwa Y; Infectious Diseases Research Collaboration, Kampala, Uganda., Tumwebaze PK; Infectious Diseases Research Collaboration, Kampala, Uganda., Katairo T; Infectious Diseases Research Collaboration, Kampala, Uganda., Byaruhanga O; Infectious Diseases Research Collaboration, Kampala, Uganda., Sievert MA; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA., Garg S; University of California, San Francisco, California, USA., Kreutzfeld OK; University of California, San Francisco, California, USA., Legac J; University of California, San Francisco, California, USA., Bailey JA; Brown University, Providence, Rhode Island, USA., Nsobya SL; Infectious Diseases Research Collaboration, Kampala, Uganda., Conrad MD; University of California, San Francisco, California, USA., Rosenthal PJ; University of California, San Francisco, California, USA., Ferdig MT; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA., Cooper RA; Dominican University of California, San Rafael, California, USA.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2024 Dec 05; Vol. 68 (12), pp. e0118324. Date of Electronic Publication: 2024 Nov 15.