Zobrazeno 1 - 10
of 29
pro vyhledávání: '"5.9 Resources and infrastructure (treatment development)"'
Autor:
Rogers, Forrest D, Bales, Karen L
Publikováno v:
Affective science, vol 3, iss 4
How should we characterize the affective lives of non-human animals? There is a large body of work studying affective processes in non-human animals, yet this work is frequently overlooked. Ideas about the affective lives of animals have varied acros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::e524e5ee287d1d5f725aa3e76cf715af
https://escholarship.org/uc/item/0h27d45q
https://escholarship.org/uc/item/0h27d45q
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-14 (2021)
Translational psychiatry, vol 11, iss 1
Translational Psychiatry
Translational psychiatry, vol 11, iss 1
Translational Psychiatry
Animal and human laboratory paradigms offer invaluable approaches to study the complex etiologies and mechanisms of alcohol use disorder (AUD). We contend that human laboratory models provide a “bridge” between preclinical and clinical studies of
Autor:
Aysha Karim, Kiani, Derek, Pheby, Gary, Henehan, Richard, Brown, Paul, Sieving, Peter, Sykora, Robert, Marks, Benedetto, Falsini, Natale, Capodicasa, Stanislav, Miertus, Lorenzo, Lorusso, Daniele, Dondossola, Gianluca Martino, Tartaglia, Mahmut Cerkez, Ergoren, Munis, Dundar, Sandro, Michelini, Daniele, Malacarne, Gabriele, Bonetti, Astrit, Dautaj, Kevin, Donato, Maria Chiara, Medori, Tommaso, Beccari, Michele, Samaja, Stephen Thaddeus, Connelly, Donald, Martin, Assunta, Morresi, Ariola, Bacu, Karen L, Herbst, Mykhaylo, Kapustin, Liborio, Stuppia, Ludovica, Lumer, Giampietro, Farronato, Matteo, Bertelli
Publikováno v:
Journal of preventive medicine and hygiene, vol 63, iss 2 Suppl 3
Animal experimentation is widely used around the world for the identification of the root causes of various diseases in humans and animals and for exploring treatment options. Among the several animal species, rats, mice and purpose-bred birds compri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff078ee07e02c0671a21b4b082deaee3
https://escholarship.org/uc/item/840590rr
https://escholarship.org/uc/item/840590rr
Publikováno v:
Neuroscience and Biobehavioral Reviews, 108, 749-770. Elsevier Limited
Neuroscience and Biobehavioral Reviews
Neuroscience and biobehavioral reviews, vol 108
Paul, E S, Sher, S, Tamietto, M, Winkielman, P & Mendl, M T 2020, ' Towards a comparative science of emotion : Affect and Consciousness in humans and animals ', Neuroscience and Biobehavioral Reviews, vol. 108, pp. 749-770 . https://doi.org/10.1016/j.neubiorev.2019.11.014
Neuroscience & Biobehavioral Reviews
Neuroscience and Biobehavioral Reviews
Neuroscience and biobehavioral reviews, vol 108
Paul, E S, Sher, S, Tamietto, M, Winkielman, P & Mendl, M T 2020, ' Towards a comparative science of emotion : Affect and Consciousness in humans and animals ', Neuroscience and Biobehavioral Reviews, vol. 108, pp. 749-770 . https://doi.org/10.1016/j.neubiorev.2019.11.014
Neuroscience & Biobehavioral Reviews
Highlights • Emotions comprise conscious, behavioural, physiological and cognitive elements. • Neural correlates of conscious emotion can be investigated in humans and animals. • Contemporary theories of consciousness have differing implication
Autor:
Boaz Arzi, Tracy L. Webb, Thomas G. Koch, Susan W. Volk, Dean H. Betts, Ashlee Watts, Laurie Goodrich, Michael S. Kallos, Amir Kol
Publikováno v:
Paediatrics Publications
Frontiers in Veterinary Science, Vol 8 (2021)
Frontiers in Veterinary Science
Frontiers in Veterinary Science, Vol 8 (2021)
Frontiers in Veterinary Science
In the past decade, the potential to translate scientific discoveries in the area of regenerative therapeutics in veterinary species to novel, effective human therapies has gained interest from the scientific and public domains. Translational researc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ba25a4b6cd0223a20f339831bce2cc
https://ir.lib.uwo.ca/paedpub/806
https://ir.lib.uwo.ca/paedpub/806
Autor:
Maya U. Sheth, Cheryl A. London, Joanne L. Tuohy, Jason A. Somarelli, William C. Eward, Suzanne Bartholf DeWitt, Amy M. Boddy, Heather L. Gardner, Kate Megquier, Shiaowen David Hsu, Jeffrey L. Thorne
Publikováno v:
Molecular biology and evolution, vol 37, iss 1
Mol Biol Evol
Mol Biol Evol
Despite a considerable expenditure of time and resources and significant advances in experimental models of disease, cancer research continues to suffer from extremely low success rates in translating preclinical discoveries into clinical practice. T
Autor:
Courtney Sakolish, Christopher C.W. Hughes, R. Hugh F. Bender, Ivan Rusyn, Zunwei Chen, Yizhong Liu, Duc T. T. Phan
Publikováno v:
Toxicology
Angiogenesis is a complex process that is required for development and tissue regeneration and it may be affected by many pathological conditions. Chemicals and drugs can impact formation and maintenance of the vascular networks; these effects may be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec4b275d9f8552efcaf63c3cb5699c0
https://escholarship.org/uc/item/9z99j335
https://escholarship.org/uc/item/9z99j335
Publikováno v:
The journal of the American Academy of Psychiatry and the Law, vol 48, iss 4
The use of animals for therapeutic benefit is well-established. For example, for individuals with a disability such as blindness, trained service dogs can enhance the ability to live independently and participate fully in society. An emotional suppor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::2499457f3a2b14aa674e52e85d44d726
https://escholarship.org/uc/item/510258kn
https://escholarship.org/uc/item/510258kn
Autor:
Qianwen Wang, Véronique Dartois, Rada M. Savic, Natasha Strydom, Eric L. Nuermberger, Jacqueline P Ernest, Nan Zhang
Publikováno v:
Annu Rev Pharmacol Toxicol
Annual review of pharmacology and toxicology, vol 61, iss 1
Annual review of pharmacology and toxicology, vol 61, iss 1
Tuberculosis (TB) kills more people than any other infectious disease. Challenges for developing better treatments include the complex pathology due to within-host immune dynamics, interpatient variability in disease severity and drug pharmacokinetic
Autor:
Howard Lee, Yoshikazu Hayashi, Delese Mimi Darko, Dan Hartman, Ling Zou, Elizabeth A. E. Green, Steven E. Kern, Kit Wun Kathy Cheung, Lawrence Lin, Terrence F. Blaschke, Paul A. Akpa, Emer Cooke, Murray Lumpkin, Jennifer L. Wilson, Carl C. Peck, Russ B. Altman, Sheng Ding, Peter W. Marks, Analía Porrás, David Mukanga, Wiltshire C. N. Johnson, Kathleen M. Giacomini, Rae Yuan
Publikováno v:
Science translational medicine, vol 12, iss 554
Sci Transl Med
Sci Transl Med
Requiring regional or in-country confirmatory clinical trials before approval of drugs already approved elsewhere delays access to medicines in low- and middle-income countries and raises drug costs. Here, we discuss the scientific and technological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16e2569e6fc18b7d1d6fc3ba9f102e6
https://escholarship.org/uc/item/3rr8c18v
https://escholarship.org/uc/item/3rr8c18v