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Publikováno v:
The Journal of Cell Biology, 2000 May . 149(4), 783-791.
Externí odkaz:
https://www.jstor.org/stable/1619840
Autor:
Paula Farias, Armen Zakarian, Jordi Molgó, Artur K. Mailyan, Maša Podunavac, Jeffrey J. Jackson, Cesar Cardenas, Hernan Huerta, Alenka Lovy
Publikováno v:
Angewandte Chemie (International ed. in English), vol 60, iss 20
Angewandte Chemie International Edition
Angewandte Chemie International Edition, 2021, 60 (20), pp.11278-11282. ⟨10.1002/anie.202102259⟩
Angew Chem Int Ed Engl
Angewandte Chemie International Edition
Angewandte Chemie International Edition, 2021, 60 (20), pp.11278-11282. ⟨10.1002/anie.202102259⟩
Angew Chem Int Ed Engl
The scalable synthesis of the oxaquinolizidine marine natural product desmethylxestospongin B is based on the early application of Ireland-Claisen rearrangement, macrolactamization, and a late-stage installation of the oxaquinolizidine units by lacta
Autor:
Jordi Heijman, Faezeh Vahdahi Hassani, Dobromir Dobrev, Issam Abu-Taha, Xiao Yan Qi, Senka Ljubojevic-Holzer, Stanley Nattel, Jiening Xiao, Dennis Hoffmann, Markus Kamler, Donald M. Bers, Feng Xiong, Louis Villeneuve
Publikováno v:
Circulation research, vol 128, iss 5
Circ Res
Circulation Research, 128(5), 619-635. LIPPINCOTT WILLIAMS & WILKINS
Circ Res
Circulation Research, 128(5), 619-635. LIPPINCOTT WILLIAMS & WILKINS
Rationale: The mechanisms underlying atrial fibrillation (AF), the most common clinical arrhythmia, are poorly understood. Nucleoplasmic Ca 2+ regulates gene expression, but the nature and significance of nuclear Ca 2+ -changes in AF are largely unkn
Autor:
Ian Parker, Jeffrey T. Lock
We previously described that cell-wide cytosolic Ca2+ transients evoked by inositol trisphosphate (IP3) are generated by two modes of Ca2+ liberation from the ER; ‘punctate’ release via an initial flurry of transient Ca2+ puffs from local cluster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fd5647c2404d265b426b09b72b1e0d
https://escholarship.org/uc/item/1079w5bq
https://escholarship.org/uc/item/1079w5bq
Autor:
Zhang, Peng, Huang, Ji-Jun, Ou-Yang, Kun-Fu, Liang, He, Li, Miao-Ling, Wang, Yi-Jie, Yang, Huang-Tian
Publikováno v:
Acta pharmacologica Sinica, vol 41, iss 12
Type 2 inositol 1,4,5-trisphosphate receptor (IP3R2) regulates the intracellular Ca2+ release from endoplasmic reticulum in human embryonic stem cells (hESCs), cardiovascular progenitor cells (CVPCs), and mammalian cardiomyocytes. However, the role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::49de09ac6e42e481a2279a60abd830a5
https://escholarship.org/uc/item/6p2359cj
https://escholarship.org/uc/item/6p2359cj
Autor:
Ryan H. Moy, Alexander Nguyen, Jia Min Loo, Norihiro Yamaguchi, Christina M. Kajba, Balaji Santhanam, Benjamin N. Ostendorf, Y. Gloria Wu, Saeed Tavazoie, Sohail F. Tavazoie
Publikováno v:
Dev Cell
Developmental cell, vol 57, iss 9
Developmental cell, vol 57, iss 9
Metastatic colonization is the primary cause of death from colorectal cancer (CRC). We employed genome-scale invivo short hairpin RNA (shRNA) screening and validation to identify 26 promoters of CRC liver colonization. Among these genes, we identifie
Autor:
Chernov, Andrei V, Hullugundi, Swathi K, Eddinger, Kelly A, Dolkas, Jennifer, Remacle, Albert G, Angert, Mila, James, Brian P, Yaksh, Tony L, Strongin, Alex Y, Shubayev, Veronica I
Publikováno v:
The Journal of biological chemistry, vol 295, iss 31
In the peripheral nerve, mechanosensitive axons are insulated by myelin, a multilamellar membrane formed by Schwann cells. Here, we offer first evidence that a myelin degradation product induces mechanical hypersensitivity and global transcriptomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::68a55642b68622f413f687e24c21e42e
https://escholarship.org/uc/item/3m86d0h4
https://escholarship.org/uc/item/3m86d0h4
Publikováno v:
Cell Calcium
Cellular Ca(2+) signals are often constrained to cytosolic micro- or nano-domains where stochastic openings of Ca(2+) channels cause large fluctuations in local Ca(2+) concentration (Ca(2+) ‘noise’). With the advent of TIRF microscopy to image th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d063eb544508aa82416185fb8a1a426
https://escholarship.org/uc/item/49t0t3kd
https://escholarship.org/uc/item/49t0t3kd
Autor:
Siting Zhu, Kunfu Ouyang, Xi Fang, Beili Zhao, Huayuan Tang, Ju Chen, Ran Jing, Christa Trexler, Yali Li, Jie Liu, Hong Wang, Zhixiang Pan
Publikováno v:
Journal of gastroenterology, vol 54, iss 5
BackgroundInositol 1,4,5-trisphosphate receptors (IP3Rs) are a family of intracellular Ca2+ release channels located on the membrane of endoplasmic reticulum, which have been shown to play critical roles in various cellular and physiological function