Zobrazeno 1 - 10
of 4 372
pro vyhledávání: '"5-hydroxymethylcytosine"'
Autor:
Shuang-Ling Wu, Lin Yang, Changcai Huang, Qing Li, Chunhui Ma, Fang Yuan, Yinglin Zhou, Xiaoyue Wang, Wei-Min Tong, Yamei Niu, Feng Jin
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Background Breast tumorigenesis is a complex and multistep process accompanied by both genetic and epigenetic dysregulation. In contrast to the extensive studies on DNA epigenetic modifications 5-hydroxymethylcytosine (5hmC) and 5-methylcyto
Externí odkaz:
https://doaj.org/article/41144b1c9892407d8819b88828740caf
Autor:
Islam Uddin, Hamid Hussain Awan, Majdi Khalid, Salman Khan, Shahid Akbar, Mahidur R. Sarker, Maher G. M. Abdolrasol, Thamer A. H. Alghamdi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract RNA modifications play an important role in actively controlling recently created formation in cellular regulation mechanisms, which link them to gene expression and protein. The RNA modifications have numerous alterations, presenting broad
Externí odkaz:
https://doaj.org/article/1ba4e7c55085401a925a7082f53dd89f
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Allergic diseases, characterized by a broad spectrum of clinical manifestations and symptoms, encompass a significant category of IgE-mediated atopic disorders, including asthma, allergic rhinitis, atopic dermatitis, and food allergies. Thes
Externí odkaz:
https://doaj.org/article/ac93fead2289428f937d313b506e17c7
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Background5-Hydroxymethylcytosine (5hmC) is an important DNA epigenetic modification that plays a vital role in tumorigenesis, progression and prognosis. Previous studies have shown that it plays an important role in the prognosis of diffuse large B-
Externí odkaz:
https://doaj.org/article/6f1bb1e96a094866845dcc2e39efe486
Autor:
Salman Khan, Islam Uddin, Mukhtaj Khan, Nadeem Iqbal, Huda M. Alshanbari, Bakhtiyar Ahmad, Dost Muhammad Khan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract RNA modifications are pivotal in the development of newly synthesized structures, showcasing a vast array of alterations across various RNA classes. Among these, 5-hydroxymethylcytosine (5HMC) stands out, playing a crucial role in gene regul
Externí odkaz:
https://doaj.org/article/c6b0432aabe84f068bb55f1143f4979b
Publikováno v:
环境与职业医学, Vol 41, Iss 3, Pp 335-341 (2024)
Arsenic, a naturally occurring metal-like chemical element, is one of the 10 chemicals of major public concerns listed by the World Health Organization as harmful to the environment and human health. It can enter the human body through breathing, int
Externí odkaz:
https://doaj.org/article/c9ce0d7fda4b49859444e66bab8d77df
Publikováno v:
BMC Women's Health, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Aberrant DNA methylation is a vital molecular alteration commonly detected in type I endometrial cancers (EC), and tet methylcytosine dioxygenase 2 (TET2) and 5-hydroxymethylcytosine (5hmC) play significant roles in DNA demethylat
Externí odkaz:
https://doaj.org/article/e06a82867885474189bc9862eed96f69
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Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Brain derived neurotrophic factor (BDNF) is the most studied trophic factor in the central nervous system (CNS), and its role in the maturation of neurons, including synapse development and maintenance has been investigated intensely for over three d
Externí odkaz:
https://doaj.org/article/9fd182a2e7d540a79816c19c66dae4ea
Publikováno v:
Biomolecules, Vol 14, Iss 11, p 1346 (2024)
The chemical modifications of DNA are of pivotal importance in the epigenetic regulation of cellular processes. Although the function of 5-methylcytosine (5mC) has been extensively investigated, the significance of 5-hydroxymethylcytosine (5hmC) has
Externí odkaz:
https://doaj.org/article/8bb0b6b9eb7242589c123ff859f2e3c8