Zobrazeno 1 - 10
of 32 712
pro vyhledávání: '"5-HT"'
Autor:
Dongna Li, Xianghuan Si, Yuanqing Hua, Yunzhi Qian, Hongjia Li, Na Lv, Qijun Fang, Xiaojuan Han, Tianshu Xu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Slow transit constipation (STC) is a long-lasting and prevalent intestinal condition, marked by hard, dry feces. The primary cause of STC may be attributed to an imbalance in the gut’s microbial community and alterations in its metabolic b
Externí odkaz:
https://doaj.org/article/feeaa74dc7644713a049af78203e170e
Autor:
Meiqin Chen, Chenlu Wang, Yinan Lin, Yanbing Chen, Wenting Xie, Xiaoting Huang, Fan Zhang, Congrui Fu, Kai Zhuang, Tingting Zou, Dan Can, Huifang Li, Shengxi Wu, Ceng Luo, Jie Zhang
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-21 (2024)
Abstract Background Depressive symptoms often occur in patients with Alzheimer's disease (AD) and exacerbate the pathogenesis of AD. However, the neural circuit mechanisms underlying the AD-associated depression remain unclear. The serotonergic syste
Externí odkaz:
https://doaj.org/article/68fae01d1fde4914afd8fb2a24557f2a
Autor:
S. E. P. Bruzzone, B. Ozenne, P. M. Fisher, G. Ortega, P. S. Jensen, V. H. Dam, C. Svarer, G. M. Knudsen, K. P. Lesch, V. G. Frokjaer
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Methylation of serotonin-related genes has been proposed as a plausible gene-by-environment link which may mediate environmental stress, depressive and anxiety symptoms. DNA methylation is often measured in blood cells, but little
Externí odkaz:
https://doaj.org/article/0d11b6c981cf49608a29cbb42ecf6bbb
Publikováno v:
Encephalitis, Vol 4, Iss 2, Pp 23-30 (2024)
Purpose In our previous study, we developed an assay system to evaluate antisocial maltreating behavior of conspecific mice using a perpetrator–victim paradigm. We also generated a mouse model for the maltreating behavior by mimicking child maltrea
Externí odkaz:
https://doaj.org/article/9df0950c571045118ad58993b7bec920
Autor:
Yaqin Wei, Xiangqing Xu, Qiang Guo, Song Zhao, Yinli Qiu, Dongli Wang, Wenwen Yu, Yani Liu, KeWei Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 1457-1466 (2024)
Cognitive dysfunction is a core symptom common in psychiatric disorders including depression that is primarily managed by antidepressants lacking efficacy in improving cognition. In this study, we report a novel dual serotonin transporter and voltage
Externí odkaz:
https://doaj.org/article/cf0330df67fe4f62ac13a4b229aaf901
Lactococcus strains with psychobiotic properties improve cognitive and mood alterations in aged mice
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
Aging often accompanies cognitive and mood disturbances. Emerging evidence indicates that specific probiotics mitigate cognitive and mood dysfunctions. Strains within Lactococcus, a subgroup of probiotics, including Lactococcus lactis and Lactococcus
Externí odkaz:
https://doaj.org/article/51f0e1eca12a42ffaf3bfed3a0316f57
Autor:
Xiang Li, Xuankai Liang, Shenglu Ma, Shulei Zhao, Wenyao Wang, Mingxing Li, Dan Feng, Man Tang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117017- (2024)
5-HT clearance, commonly mediated by transporters in the uptake-1 and uptake-2 families, has been linked to 5-HT1B receptor’s action on behaviors. Since no specific transporters identified yet, effects of serotonin transporter (SERT) and organic ca
Externí odkaz:
https://doaj.org/article/32c01493e99c48539e15445663f510cd
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 280, Iss , Pp 116521- (2024)
The aim of this study is to investigate the role of estrogen receptor β (ERβ) in nonylphenol (NP) - induced depression - like behavior in rats and its impact on the regulation of the TPH2/5-HT pathway. In the in vitro experiment, rat basophilic leu
Externí odkaz:
https://doaj.org/article/6cb7bdf552b74186838fd2d3408ed638
Autor:
Juan Francisco Fernández-González, José Ángel García-Pedraza, Anaïs Clara Terol-Úbeda, María Luisa Martín, Asunción Morán, Mónica García-Domingo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116814- (2024)
Diabetes and derived complications, especially diabetic nephropathy and neuropathy annually cause great morbimortality worldwide. 5-hydroxytryptamine (5-HT) acts as a modulator of renal sympathetic input and vascular tone. In this line, 5-HT2 recepto
Externí odkaz:
https://doaj.org/article/a9748e27efe14eca971c09e3d9c618f7