Zobrazeno 1 - 10
of 74
pro vyhledávání: '"5α-Dihydroprogesterone"'
Autor:
Sabina Luchetti, Philippe Liere, Antoine Pianos, Ronald W.H. Verwer, Arja Sluiter, Inge Huitinga, Michael Schumacher, Dick F. Swaab, Matthew R.J. Mason
Publikováno v:
Neurobiology of Disease, Vol 183, Iss , Pp 106169- (2023)
Neuroactive steroids are known neuroprotective agents and neurotransmitter regulators. We previously found that expression of the enzymes synthesizing 5α-dihydroprogesterone (5α-DHP), allopregnanolone (ALLO), and dehydroepiandrosterone sulfate (DHE
Externí odkaz:
https://doaj.org/article/98b77096537a4453ac25d7b3fb869775
Akademický článek
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Autor:
Anna Ferrari, Cecilia Rustichelli, Elisa Bellei, Stefania Bergamini, Rossella Avallone, Aldo Tomasi, Emanuela Monari
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 206
Migraine is a very painful, disabling and extremely common disorder among the world's adult population, especially women, and it is associated with a variety of comorbidities. Neuroactive steroids exhibit pleiotropic actions on the nervous system. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc4458a4795341e04a7bcf7685e39a1a
https://pubmed.ncbi.nlm.nih.gov/34597839
https://pubmed.ncbi.nlm.nih.gov/34597839
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Yinhao Violet Wu, W. McIntyre Burnham
Publikováno v:
Epilepsy research. 146
Objective The present study investigated the anti-seizure effects of 5α-dihydroprogesterone (DHP) in an animal model of human drug-resistant focal seizures with impaired awareness. DHP was administered via the intravenous (IV) route. Methods Female
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482c55f567e512d9a73e104b385d1788
https://pubmed.ncbi.nlm.nih.gov/30149307
https://pubmed.ncbi.nlm.nih.gov/30149307
Autor:
Ghislaine A. Dujovne, E. L. Scholtz, Benjamin C. Moeller, C. J. Corbin, Barry A. Ball, Heather K Knych, Scott D Stanley, Alan J Conley, Erin L. Legacki
Publikováno v:
The Journal of endocrinology. 238(1)
In vivoandin vitroevidence indicates that the bioactive, 5α-reduced progesterone metabolite, 5α-dihydroprogesterone (DHP) is synthesized in the placenta, supporting equine pregnancy, but its appearance in early pregnancy argues for other sites of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64593080ff9bf35a197b30c796b8a26
https://pubmed.ncbi.nlm.nih.gov/29853526
https://pubmed.ncbi.nlm.nih.gov/29853526
Autor:
Tatsuhiko Hoshii, Tsutomu Nishiyama, Yoshihiko Tomita, Takashi Ando, Itsuhiro Takizawa, Noboru Hara, Yoshimichi Miyashiro
Publikováno v:
Journal of Urology. 197
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::259c42be9b4f96a36876903b4daf3a87
https://doi.org/10.1016/j.juro.2017.02.2586
https://doi.org/10.1016/j.juro.2017.02.2586
Autor:
K. J. McDowell, Benjamin C. Moeller, Alan J Conley, C. Jo Corbin, Austin L. Hughes, Barry A. Ball, Scott D Stanley, Donald P. McDonnell, E. L. Scholtz, Shweta Krishnan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 111, iss 9
One of the most widely accepted axioms of mammalian reproductive biology is that pregnancy requires the (sole) support of progesterone, acting in large measure through nuclear progesterone receptors (PRs) in uterine and cervical tissues, without whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b43d02b602e2cde18a817432b6f7d2
https://doi.org/10.1073/pnas.1318163111
https://doi.org/10.1073/pnas.1318163111
Autor:
Abdel M. Ghoumari, Florencia Labombarda, Michael Schumacher, Rachida Guennoun, Regine Sitruk-Ware, Claudia Mattern, Jean-Paul Oudinet, Philippe Liere, A. F. De Nicola
Publikováno v:
Progress in Neurobiology. 113:6-39
Progesterone is commonly considered as a female reproductive hormone and is well-known for its role in pregnancy. It is less well appreciated that progesterone and its metabolite allopregnanolone are also male hormones, as they are produced in both s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adaac2dd69ca4bb579a9654d48dc5348
https://doi.org/10.1016/j.pneurobio.2013.09.004
https://doi.org/10.1016/j.pneurobio.2013.09.004
Publikováno v:
Neuroscience. 257:65-75
Progesterone is a known anticonvulsant, with its inhibitory effects generally attributed to its secondary metabolite, 5α,3α-tetrahydroprogesterone (THP), and THP's enhancement of GABAA receptor activity. Accumulating evidence, however, suggests tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34548c7e4e325061b7508e754865f01f
https://doi.org/10.1016/j.neuroscience.2013.10.074
https://doi.org/10.1016/j.neuroscience.2013.10.074