Zobrazeno 1 - 10
of 649
pro vyhledávání: '"5'UTR"'
Autor:
Claire Lescoat, Delphine Perrotte, Séverine Barry, Élise Oden, Valentin Herbet, Gaël Beaunée, Marc Tabouret, Fabienne Benoit, Pierre-Hugues Pitel, Véronique Duquesne, Xavier Bailly, Julien Thézé, Guy Kouokam
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-16 (2024)
Abstract Bovine viral diarrhoea (BVD) is one of the most economically damaging livestock enzootic diseases in the world. BVD aetiological agents are three pestiviruses (BVDV-1, -2 and HoBi-like pestivirus), which exhibit high genetic diversity and co
Externí odkaz:
https://doaj.org/article/c7ea8d35ec3d4c61a33efa4ce6ab4207
Autor:
Xiaoying Xu, Shao Ma, Ziwei Liu, Haowen Yuan, Yao Wang, Mengting Chen, Mengyu Du, Haopeng Kan, Zequn Wang, Xiaowen Chong, Hongling Wen
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Background EV71 is one of the important pathogens of Hand-foot-and-mouth disease (HFMD), which causes serious neurological symptoms. Several studies have speculated that there will be interaction between 5′UTR and 3D protein. However, whet
Externí odkaz:
https://doaj.org/article/9574eca6bc2e4e8ca780abba813b9bc7
Autor:
Nechama Wieder, Elston N. D’Souza, Alexandra C. Martin-Geary, Frederik H. Lassen, Jonathan Talbot-Martin, Maria Fernandes, Sonia P. Chothani, Owen J. L. Rackham, Sebastian Schafer, Julie L. Aspden, Daniel G. MacArthur, Robert W. Davies, Nicola Whiffin
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Untranslated regions (UTRs) are important mediators of post-transcriptional regulation. The length of UTRs and the composition of regulatory elements within them are known to vary substantially across genes, but little is known ab
Externí odkaz:
https://doaj.org/article/419dbeb079c94514871454c4158e40f1
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background Interleukin-38 (IL-38), an inflammatory cytokine discovered in recent years, has been implicated in the pathogenesis of systemic lupus erythematosus (SLE). IL-38 is encoded by the IL1F10 (interleukin 1 family member 10) gene. Gene
Externí odkaz:
https://doaj.org/article/6c3ba4ea6bf04af089d73aa282f57571
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Escherichia coli is one of the most commonly used host organisms for the production of biopharmaceuticals, as it allows for cost-efficient and fast recombinant protein expression. However, challenging proteins are often produced w
Externí odkaz:
https://doaj.org/article/93d50a42567845869d7effb801bb5aac
Autor:
Alfredo Dueñas Rey, Marta del Pozo Valero, Manon Bouckaert, Katherine A Wood, Filip Van den Broeck, Malena Daich Varela, Huw B Thomas, Mattias Van Heetvelde, Marieke De Bruyne, Stijn Van de Sompele, Miriam Bauwens, Hanne Lenaerts, Quinten Mahieu, Dragana Josifova, Genomics England Research Consortium, Carlo Rivolta, Raymond T O’Keefe, Jamie Ellingford, Andrew R Webster, Gavin Arno, Carmen Ayuso, Julie De Zaeytijd, Bart P Leroy, Elfride De Baere, Frauke Coppieters
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Background 5’ untranslated regions (5’UTRs) are essential modulators of protein translation. Predicting the impact of 5’UTR variants is challenging and rarely performed in routine diagnostics. Here, we present a combined approach of a
Externí odkaz:
https://doaj.org/article/3ef1b0b6663c4cf89d5498ab57ec00ff
Autor:
Jinyang Li, Yidi Wang, Kun Yang, Xiaolu Wang, Yuan Wang, Honglian Zhang, Huoqing Huang, Xiaoyun Su, Bin Yao, Huiying Luo, Xing Qin
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-10 (2023)
Abstract Background Thermophilic fungus Myceliophthora thermophila has been widely used in industrial applications due to its ability to produce various enzymes. However, the lack of an efficient protein expression system has limited its biotechnolog
Externí odkaz:
https://doaj.org/article/ffc9164d46e4486f9a6cafcc494f6b63
Publikováno v:
Balkan Journal of Medical Genetics, Vol 26, Iss 1, Pp 51-56 (2023)
Sexual development (SD) is a complex process with strict spatiotemporal regulation of gene expression. Despite advancements in molecular diagnostics, disorders of sexual development (DSD) have a diagnostic rate of ~50%. Androgen insensitivity syndrom
Externí odkaz:
https://doaj.org/article/f4c7c783593746839b7c308f38000c62
Autor:
Li Song, Qiu‐Ling Pan, Gui‐Feng Zhou, Sheng‐Wei Liu, Bing‐Lin Zhu, Pei‐Jia Lin, Xiao‐Tong Hu, Jing‐Si Zha, Yan Long, Biao Luo, Jian Chen, Ying Tang, Jing Tang, Xiao‐Jiao Xiang, Xiao‐Yong Xie, Xiao‐Juan Deng, Guo‐Jun Chen
Publikováno v:
Advanced Science, Vol 11, Iss 11, Pp n/a-n/a (2024)
Abstract It is long been suggested that one‐carbon metabolism (OCM) is associated with Alzheimer's disease (AD), whereas the potential mechanisms remain poorly understood. Taking advantage of chemical biology, that mitochondrial serine hydroxymethy
Externí odkaz:
https://doaj.org/article/05748bcfdf2b4138810dae2b4810b884
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
IntroductionAmong candidate genes underlying the control components of apomixis, APOLLO is known for its strong linkage to apomeiosis in the genus Boechera. The gene has “apo alleles,” which are characterized by a set of linked apomixis-specific
Externí odkaz:
https://doaj.org/article/a0cb54fb85a94e2bba9ff77fc3bed78a