Zobrazeno 1 - 10
of 247
pro vyhledávání: '"4EBP1"'
Publikováno v:
Breast Cancer: Targets and Therapy, Vol Volume 15, Pp 11-24 (2023)
Jing Ma,1 Chao Dong,1 Yan-Zhen Cao,2 Bin-Lin Ma1 1Department of Breast and Thyroid Surgery, Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, 830000, People’s Republic of China; 2Pathology Center, Affiliated Cancer Hospital of Xinj
Externí odkaz:
https://doaj.org/article/34b5548706144ca8ac4a0b05efd4962d
Autor:
Cecilia Vittori, Duane Jeansonne, Hassan Yousefi, Celeste Faia, Zhen Lin, Krzysztof Reiss, Francesca Peruzzi
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-19 (2022)
Abstract Background Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by the lack of estrogen receptor, progesterone receptor, and HER2. Our lab previously characterized miR-3189-3p as a microRNA with potent
Externí odkaz:
https://doaj.org/article/50e466798e054fefa563895299e8f22f
Publikováno v:
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, Vol 29, Iss 4, Pp 3658-3668 (2021)
Introduction: Physiological hypertrophy of the heart is dependent on cellular pathways and important proteins such as the ribosomal protein S6 kinase beta-1 (S6K1) and eukaryotic translation intiation factor4E-binding protein-1(4EBP1). The aim of thi
Externí odkaz:
https://doaj.org/article/09ede5f6b6514ad4bf89060c9b43b555
Autor:
Kunpeng Du, Jingwen Zou, Chunshan Liu, Muhammad Khan, Tao Xie, Xiaoting Huang, Ke Zhang, Yawei Yuan, Baiyao Wang
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (4EBP1) involved in inhibition of protein translation and synthesis. However, the phosphoprotein of 4EBP1 (p-4EBP1) promotes the translation and synthesis of several proteins,
Externí odkaz:
https://doaj.org/article/815bae26c9d344b98e9cfbcc7241537d
Akademický článek
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Autor:
Bianca J. Lee, Sharmila Mallya, Nuntana Dinglasan, Amos Fung, Tram Nguyen, Lee-or Herzog, Joshua Thao, Edward G. Lorenzana, David Wildes, Mallika Singh, Jacqueline A. M. Smith, David A. Fruman
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The mechanistic target of rapamycin (mTOR) is a kinase whose activity is elevated in hematological malignancies. mTOR-complex-1 (mTORC1) phosphorylates numerous substrates to promote cell proliferation and survival. Eukaryotic initiation factor 4E (e
Externí odkaz:
https://doaj.org/article/0ce53ca3736040b0b923689cf9147f19
Autor:
Alexandria C. Rutkovsky, Elizabeth S. Yeh, Stephen T. Guest, Victoria J. Findlay, Robin C. Muise-Helmericks, Kent Armeson, Stephen P. Ethier
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-15 (2019)
Abstract Background Eukaryotic Initiation Factor 4E-Binding Protein (EIF4EBP1, 4EBP1) is overexpressed in many human cancers including breast cancer, yet the role of 4EBP1 in breast cancer remains understudied. Despite the known role of 4EBP1 as a ne
Externí odkaz:
https://doaj.org/article/8b8d8c29637d4da3a5c4925419097c71
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Cardiac glycosides are plant-derived steroid-like compounds which have been used for the treatment of cardiovascular diseases. Ouabain, a cardiotonic steroid and specific Na+/K+-ATPase inhibitor, has been rediscovered for its potential use in the tre
Externí odkaz:
https://doaj.org/article/1e4a2ae785724adab0f9062523945093
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Juliana, Christine A., Yang, Juxiang, Rozo, Andrea V., Good, Austin, Groff, David N., Wang, Shu-Zong, Green, Michael R., Stoffers, Doris A.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Feb 01. 114(6), 1341-1346.
Externí odkaz:
https://www.jstor.org/stable/26479218