Zobrazeno 1 - 10
of 63
pro vyhledávání: '"4D nucleome"'
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
The mammalian genome is intricately folded in a three-dimensional topology believed to be important for the orchestration of gene expression regulating development, differentiation and tissue homeostasis. Important features of spatial genome conforma
Externí odkaz:
https://doaj.org/article/3913b873338a4e1ea970ab9bd4de1501
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 14, Iss 1, Pp 7-20 (2016)
The manner by which eukaryotic genomes are packaged into nuclei while maintaining crucial nuclear functions remains one of the fundamental mysteries in biology. Over the last ten years, we have witnessed rapid advances in both microscopic and nucleic
Externí odkaz:
https://doaj.org/article/ee5787b7071149bd8aefc2665403c26d
Autor:
Chen, Haiming, Chen, Jie, Muir, Lindsey A., Ronquist, Scott, Meixner, Walter, Ljungman, Mats, Ried, Thomas, Smale, Stephen, Rajapakse, Indika
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Jun . 112(26), 8002-8007.
Externí odkaz:
https://www.jstor.org/stable/26463624
Autor:
Ma, Hanhui, Naseri, Ardalan, Reyes-Gutierrez, Pablo, Wolfe, Scot A., Zhang, Shaojie, Pederson, Thoru
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Mar 01. 112(10), 3002-3007.
Externí odkaz:
https://www.jstor.org/stable/26461756
Autor:
Marc A. Marti-Renom, Mike N. Goodstadt
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
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Genome discoveries at the core of biology are made by visual description and exploration of the cell, from microscopic sketches and biochemical mapping to computational analysis and spatial modeling. We outline the experimental and visualization tech
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Publikováno v:
Journal of Cellular and Molecular Medicine
Colon crypts are recognized as a mechanical and biochemical Turing patterning model. Colon epithelial Caco‐2 cell monolayer demonstrated 2D Turing patterns via force analysis of apical tight junction live cell imaging which illuminated actomyosin m
Fit-Hi-C is a programming application to compute statistical confidence estimates for Hi-C contact maps to identify significant chromatin contacts. By fitting a monotonically non-increasing spline, Fit-Hi-C captures the relationship between genomic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af1c6cf5623b5233300155c094e5dc7
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 10 (2019)
Frontiers in Genetics, Vol 10 (2019)
The mammalian genome is intricately folded in a three-dimensional topology believed to be important for the orchestration of gene expression regulating development, differentiation and tissue homeostasis. Important features of spatial genome conforma
Publikováno v:
Methods, 170, 17-32. Elsevier Science
Methods. Academic Press
Methods. Academic Press
Chromosome conformation capture (3C) methods measure DNA contact frequencies based on nuclear proximity ligation, to uncover in vivo genomic folding patterns. 4C-seq is a derivative 3C method, designed to search the genome for sequences contacting a