Zobrazeno 1 - 10
of 13
pro vyhledávání: '"49/91"'
Autor:
B. Edginton-White, A. Maytum, S. G. Kellaway, D. K. Goode, P. Keane, I. Pagnuco, S. A. Assi, L. Ames, M. Clarke, P. N. Cockerill, B. Göttgens, J. B. Cazier, C. Bonifer
Developmental control of gene expression critically depends on distal cis-regulatory elements including enhancers which interact with promoters to activate gene expression. To date no global experiments have been conducted that identify their cell ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89095f57d609624e4da8fd53cc0eb563
Autor:
Dayana E. Salas-Leiva, Bruce A. Curtis, Zhenzhen Yi, Martin Kolisko, Shelby K Williams, Jon Jerlström-Hultqvist, Joan Salas-Leiva, Lucie Gallot-Lavallée, Geert J. P. L. Kops, John M. Archibald, Alastair G. B. Simpson, Andrew J. Roger, Eelco C. Tromer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications, 12(1):6003. Nature Publishing Group
Nature Communications, 12(1). Nature Publishing Group
Nature Communications
Nature Communications, 12(1):6003. Nature Publishing Group
Nature Communications, 12(1). Nature Publishing Group
Funder: Canadian Institutes of Health Research (Grant: FRN-142349) Natural Sciences and Engineering Research Council of Canada (Grant: RGPIN 05871-2014)
Cells replicate and segregate their DNA with precision. Previous studies showed that these r
Cells replicate and segregate their DNA with precision. Previous studies showed that these r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80a3bd35785b4ff3fc4f174ab0ad9f0
https://doaj.org/article/53b88dba845e440e95e7fa4a170fb0c8
https://doaj.org/article/53b88dba845e440e95e7fa4a170fb0c8
Autor:
Thi Tran, Jean-Remi Lavillegrand, Cedric Lereverend, Bruno Esposito, Lucille Cartier, Melanie Montabord, Jaouen Tran-Rajau, Marc Diedisheim, Nadège Gruel, Khadija Ouguerram, Lea Paolini, Olivia Lenoir, Emmanuel Pinteaux, Eva Brabencova, Corinne Tanchot, Pauline Urquia, Jacqueline Lehmann-Che, Richard Le Naour, Yacine Merrouche, Christian Stockmann, Ziad Mallat, Alain Tedgui, Hafid Ait-Oufella, Eric Tartour, Stephane Potteaux
Publikováno v:
Nature Communications
Nature Communications, 2022, 13 (1), pp.5399. ⟨10.1038/s41467-022-33034-0⟩
Nature Communications, 2022, 13 (1), pp.5399. ⟨10.1038/s41467-022-33034-0⟩
Funder: Association pour la recherche sur le cancer
Funder: Ligue Contre le Cancer
Cancer and cardiovascular disease (CVD) share common risk factors such as dyslipidemia, obesity and inflammation. However, the role of pro-atherogenic enviro
Funder: Ligue Contre le Cancer
Cancer and cardiovascular disease (CVD) share common risk factors such as dyslipidemia, obesity and inflammation. However, the role of pro-atherogenic enviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39cc252d6c5adb79687287294bc8a7f4
Autor:
Maik Pietzner, Robert Lorenz Chua, Eleanor Wheeler, Katharina Jechow, Julian D. S. Willett, Helena Radbruch, Saskia Trump, Bettina Heidecker, Hugo Zeberg, Frank L. Heppner, Roland Eils, Marcus A. Mall, J. Brent Richards, Leif-Erik Sander, Irina Lehmann, Sören Lukassen, Nicholas J. Wareham, Christian Conrad, Claudia Langenberg
Publikováno v:
Nature Communications
Nature Communications 13(1), 4484 (2022). doi:10.1038/s41467-022-31999-6
Nature Communications 13(1), 4484 (2022). doi:10.1038/s41467-022-31999-6
Funder: Wellcome Trust
Funder: National Institute for Health Research (NIHR)
Despite two years of intense global research activity, host genetic factors that predispose to a poorer prognosis of COVID-19 infection remain poorly understood. H
Funder: National Institute for Health Research (NIHR)
Despite two years of intense global research activity, host genetic factors that predispose to a poorer prognosis of COVID-19 infection remain poorly understood. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16738ccadd0ecff30336a65e217948cd
Autor:
Elena Spina, Julia Simundza, Angela Incassati, Anupama Chandramouli, Matthias C. Kugler, Ziyan Lin, Alireza Khodadadi-Jamayran, Christine J. Watson, Pamela Cowin
Funder: The Susan G Komen Foundation For The Cure
Funder: Will-Rogers and the Stony Wold-Herbert Foundation
Funder: U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI)
Funder: NYC Peter Rowley award C0285
Funder: Will-Rogers and the Stony Wold-Herbert Foundation
Funder: U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI)
Funder: NYC Peter Rowley award C0285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef2f77eaec946dc2a1d3455912713f2
Autor:
Xiangjun Liu, Shanzhao Jin, Simeng Hu, Ruoyan Li, Haihao Pan, Yi Liu, Pan Lai, Deshu Xu, Jingru Sun, Ziyang Liu, Yumei Gao, Yifan Zhao, Fengjie Liu, Yu Xiao, Yingyi Li, Yujie Wen, Zhuojing Chen, Bufang Xu, Yuchieh Lin, Menglong Ran, Qianxi Li, Shuxia Yang, Hang Li, Ping Tu, Muzlifah Haniffa, Sarah A. Teichmann, Fan Bai, Yang Wang
Funder: National Nature Science Foundation of China 81922058 National Science and Technology Major Project 2019YFC1315702 Guangdong Province Key Research and Development Program 2019B020226002 National Youth Top-Notch Talent Support Program 283812 Pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55cc869f3aded0b293aab13e9b318dd0
https://www.repository.cam.ac.uk/handle/1810/334643
https://www.repository.cam.ac.uk/handle/1810/334643
Autor:
Fielding, Claire, García-García, Andrés, Korn, Claudia, Gadomski, Stephen, Fang, Zijian, Reguera, Juan L, Pérez-Simón, José A, Gottgens, Berthold, Méndez-Ferrer, Simón
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
The sympathetic nervous system has been evolutionary selected to respond to stress and activates haematopoietic stem cells via noradrenergic signals. However, the pathways preserving haematopoietic stem cell quiescence and maintenance under prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c19135813718229894b3a5083e7954
https://doi.org/10.1038/s41467-022-28175-1
https://doi.org/10.1038/s41467-022-28175-1
Autor:
Hamed, Akram A, Kunz, Daniel J, El-Hamamy, Ibrahim, Trinh, Quang M, Subedar, Omar D, Richards, Laura M, Foltz, Warren, Bullivant, Garrett, Ware, Matthaeus, Vladoiu, Maria C, Zhang, Jiao, Raj, Antony M, Pugh, Trevor J, Taylor, Michael D, Teichmann, Sarah A, Stein, Lincoln D, Simons, Benjamin D, Dirks, Peter B
Publikováno v:
Nature communications. 13(1)
Funder: Canadian Institute of Health Research (155960)
Human cerebral cancers are known to contain cell types resembling the varying stages of neural development. However, the basis of this association remains unclear. Here, we map the developme
Human cerebral cancers are known to contain cell types resembling the varying stages of neural development. However, the basis of this association remains unclear. Here, we map the developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c7a1d0cd98edcfcafef5755533b59f
https://pubmed.ncbi.nlm.nih.gov/35853870
https://pubmed.ncbi.nlm.nih.gov/35853870
Autor:
Silvain Pinaud, Karsten Bach, Marija Zarocsinceva, Sacha J Howell, Sara Pensa, Carlos Caldas, Katarzyna D. Kania, Bruno M Simões, John C. Marioni, Alice R. Greenhalgh, Julie Stockis, Mona Shehata, Walid T. Khaled, Kyren A. Lazarus, Timotheus Y.F. Halim, Robert Clarke
Publikováno v:
Bach, K, Pensa, S, Zarocsinceva, M, Kania, K, Stockis, J, Pinaud, S, Lazarus, K A, Shehata, M, Simões, B M, Greenhalgh, A R, Howell, S J, Clarke, R B, Caldas, C, Halim, T Y F, Marioni, J C & Khaled, W T 2021, ' Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors ', Nature Communications, vol. 12, no. 1 . https://doi.org/10.1038/s41467-021-21783-3
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
It is unclear how genetic aberrations impact the state of nascent tumour cells and their microenvironment. BRCA1 driven triple negative breast cancer (TNBC) has been shown to arise from luminal progenitors yet little is known about how BRCA1 loss-of-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24be004e59da16b4cf960b7624ca74bc
Autor:
Martin J. Genner, Eric A. Miska, M. Emília Santos, George F. Turner, Milan Malinsky, Mingliu Du, Grégoire Vernaz, Alexandra M. Tyers, Richard Durbin, Hannes Svardal
Publikováno v:
Nature communications
Nature Communications
Vernaz, G, Malinsky, M, Svardal, H, Du, M, Tyers, A M, Santos, M E, Durbin, R, Genner, M J, Turner, G F & Miska, E A 2021, ' Mapping epigenetic divergence in the massive radiation of Lake Malawi cichlid fishes ', Nature Communications, vol. 12, no. 1, 5870 . https://doi.org/10.1038/s41467-021-26166-2
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Vernaz, G, Malinsky, M, Svardal, H, Du, M, Tyers, A M, Santos, M E, Durbin, R, Genner, M J, Turner, G F & Miska, E A 2021, ' Mapping epigenetic divergence in the massive radiation of Lake Malawi cichlid fishes ', Nature Communications, vol. 12, no. 1, 5870 . https://doi.org/10.1038/s41467-021-26166-2
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Epigenetic variation modulates gene expression and can be heritable. However, knowledge of the contribution of epigenetic divergence to adaptive diversification in nature remains limited. The massive evolutionary radiation of Lake Malawi cichlid fish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e43bed2c11e724080ad4ea6f5733f1
https://doi.org/10.1101/2020.11.24.383034
https://doi.org/10.1101/2020.11.24.383034