Zobrazeno 1 - 10
of 567
pro vyhledávání: '"4-hydroxytamoxifen"'
Autor:
Desai, Omkar a, 1, Köster, Mario a, 1, Kloos, Doreen b, Lachmann, Nico b, c, d, e, f, Hauser, Hansjörg a, g, Poortinga, Albert h, Wirth, Dagmar a, i, ⁎
Publikováno v:
In Journal of Controlled Release 10 February 2025 378:365-376
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e25598- (2024)
Breast cancer treatment options are diverse, with tamoxifen commonly used as a selective estrogen receptor modulator (SERM) for hormone receptor-positive breast cancer. However, tamoxifen can have adverse systemic effects. Local transdermal therapy o
Externí odkaz:
https://doaj.org/article/7448f8eca43842019b42073d1c136e97
Autor:
Diana I. Salnikova, Stepan K. Krymov, Danila V. Sorokin, Fedor B. Bogdanov, Olga E. Andreeva, Alvina I. Khamidullina, Andrey E. Shchekotikhin, Alexander M. Scherbakov
Publikováno v:
Proceedings, Vol 100, Iss 1, p 4 (2024)
Introduction: The design and development of antitumor compounds based on an isatin core led to the synthesis of 1-substituted isatin-5-sulfonamides with potent antiproliferative activity [...]
Externí odkaz:
https://doaj.org/article/1374ebb7d9014592ae7a54f751b6d95c
Autor:
Stepan K. Krymov, Diana I. Salnikova, Lyubov G. Dezhenkova, Fedor B. Bogdanov, Alexander A. Korlyukov, Alexander M. Scherbakov, Andrey E. Shchekotikhin
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 32 (2023)
Breast and other estrogen receptor α-positive cancers tend to develop resistance to existing drugs. Chalcone derivatives possess anticancer activity based on their ability to form covalent bonds with targets acting as Michael acceptors. This study a
Externí odkaz:
https://doaj.org/article/bbd2de3f85e34d55b95a8907e749723a
Autor:
Danila Vladimirovich Sorokin, Stepan K. Krymov, Margo N. Cherednichenko, Alexandra L. Mikhaylova, Diana I. Salnikova, Andrey E. Shchekotikhin, Alexander M. Scherbakov
Publikováno v:
Engineering Proceedings, Vol 56, Iss 1, p 192 (2023)
Cancer is one of the leading causes of death worldwide, accounting for about 10 million deaths a year, or nearly one in six deaths. The most common types of cancer are breast, colorectal, lung, and prostate cancers. Prolonged application of hormone d
Externí odkaz:
https://doaj.org/article/8a14a4bcc81748b7bb8579e185b9f9e3
Autor:
Hong-Yan Lin, Hong-Wei Han, Yin-Song Wang, De-Liu He, Wen-Xue Sun, Lu Feng, Zhong-Ling Wen, Min-Kai Yang, Gui-Hua Lu, Xiao-Ming Wang, Jin-Liang Qi, Yong-Hua Yang
Publikováno v:
Chinese Medicine, Vol 15, Iss 1, Pp 1-14 (2020)
Abstract Background Tamoxifen (TAM) is a cell type-specific anti-estrogen and is applied to improve the survival of patients with estrogen receptor positive (ER +) breast cancer. However, long-term TAM use can induce serious drug resistance, leading
Externí odkaz:
https://doaj.org/article/df00be6842d54f5eaec3dbbccef0f6f9
Publikováno v:
Membranes, Vol 13, Iss 3, p 292 (2023)
Tamoxifen (TMX), commonly used in complementary therapy for breast cancer, also displays known effects on the structure and function of biological membranes. This work presents an experimental and simulation study on the permeabilization of model pho
Externí odkaz:
https://doaj.org/article/720e66ad4a474e038f3c72304ac1641c
Akademický článek
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Autor:
Ada Weinstock, Julio Gallego-Delgado, Cláudia Gomes, Julian Sherman, Cyrus Nikain, Sandra Gonzalez, Edward Fisher, Ana Rodriguez
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-7 (2019)
Abstract Background Tamoxifen is an oestrogen receptor modulator that is widely used for the treatment of early stage breast cancer and reduction of recurrences. Tamoxifen is also used as a powerful research tool for controlling gene expression in th
Externí odkaz:
https://doaj.org/article/83d7cc351ab34d0bb72738749910afa7
Akademický článek
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