Zobrazeno 1 - 10
of 809
pro vyhledávání: '"4-HNE"'
Autor:
Soon-Young Lee, Yeon-Kyoung Cho, Chun-Sik Bae, Gyeyeop Kim, Min-Jae Lee, Seung-Sik Cho, In-Chul Jeon, Dae-Hun Park
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Age-related macular degeneration (AMD) is one of the leading causes of blindness. AMD is currently incurable; the best solution is to prevent its occurrence. To develop drugs for AMD, it is crucial to have a model system that mimics the symp
Externí odkaz:
https://doaj.org/article/57e3082ea0474750aeb9f0ea933ed1bb
Autor:
Eva Tsoneva, Polina Dimitrova, Metodi Metodiev, Velizar Shivarov, Mariela Vasileva-Slaveva, Angel Yordanov, Stoyan Kostov
Publikováno v:
Menopause Review, Vol 23, Iss 1, Pp 6-13 (2024)
Externí odkaz:
https://doaj.org/article/c91b63172aea4a2f9dead88c5fc8b733
Autor:
Ying-Wei Lan, Wan-Ru Chen, Gary Ro-Lin Chang, Ying-Cheng Chen, Kowit-Yu Chong, Kai-Cheng Chuang, Yung-Tsung Kao, Ming-Shan Chen, Chuan-Mu Chen
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Background The development of alcohol-associated liver disease (ALD) is influenced by the amount and duration of alcohol consumption. The resulting liver damage can range from reversible stages, such as steatosis, steatohepatitis and alcohol
Externí odkaz:
https://doaj.org/article/18b6d4dd9b68443ca176d4d249c0ecbd
Akademický článek
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Autor:
Neven Žarković, Agnieszka Gęgotek, Wojciech Łuczaj, Morana Jaganjac, Suzana Borović Šunjić, Kamelija Žarković, Elzbieta Skrzydlewska
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 4, p 153 (2024)
Oxidative stress often affects the structure and metabolism of lipids, which in the case of polyunsaturated free fatty acids (PUFAs) leads to a self-catalysed chain reaction of lipid peroxidation (LPO). The LPO of PUFAs leads to the formation of vari
Externí odkaz:
https://doaj.org/article/3e1d8e9059fa4cd68bc4fdffac49f8bb
Autor:
Florentina Piciu, Dan Domocos, Gabriela Chiritoiu, Marioara Chiritoiu-Butnaru, Maria Mernea, Cezar Gabriel Popescu, Dragos Paul Mihai, Bianca Galateanu, Ariana Hudita, Alexandru Babes, Dana Cucu
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 344 (2024)
Background: Transient receptor potential channels (TRP) are overexpressed in some pancreatic adenocarcinoma (PDAC) patients and cell lines, settling them as putative therapeutic targets in this disease. Reactive oxygen species (ROS), with levels incr
Externí odkaz:
https://doaj.org/article/29f94653a46e4b2c8c8115ee98efdea9
Autor:
Lulu Liu, Jiaojiao Pang, Dandan Qin, Ruochuan Li, Dan Zou, Kai Chi, Wenxiao Wu, Haiying Rui, Huaxiang Yu, Wenyong Zhu, Kai Liu, Xuting Wu, Jinxin Wang, Ping Xu, Xiaoshuai Song, Yihai Cao, Jiali Wang, Feng Xu, Li Xue, Yuguo Chen
Publikováno v:
Advanced Science, Vol 10, Iss 28, Pp n/a-n/a (2023)
Abstract Despite the development of advanced technologies for interventional coronary reperfusion after myocardial infarction, a substantial number of patients experience high mortality due to myocardial ischemia‐reperfusion (MI/R) injury. An in‐
Externí odkaz:
https://doaj.org/article/bf70f1bc9a674fac9a170ff5b88f44e6
Autor:
Felix Sternberg, Christina Sternberg, Andreas Dunkel, Taraneh Beikbaghban, András Gregor, Aleksander Szarzynski, Veronika Somoza, Ingrid Walter, Kalina Duszka, Barbara Kofler, Elena E. Pohl
Publikováno v:
Molecular Metabolism, Vol 72, Iss , Pp 101711- (2023)
Purpose: Heart diseases are the leading cause of death worldwide. Metabolic interventions via ketogenic diets (KDs) have been used for decades to treat epilepsy, and more recently, also diabetes and obesity, as common comorbidities of heart diseases.
Externí odkaz:
https://doaj.org/article/2f05f1f0fd4f421a944949aab7c53f7d
Autor:
R.A. Skolik, C. Noud, S. Oliver, J. Markitan, L. Salazar, M Asante, W.J. Geldenhuys, M.E. Konkle, M.A. Menze
Publikováno v:
Advances in Redox Research, Vol 7, Iss , Pp 100059- (2023)
MitoNEET is a mitochondrial [2Fe-2S]-containing protein known for its involvement in cellular metabolism, iron regulation, and oxidative stress. The protein has been associated with diseases ranging from diabetes to Parkinson's disease, prompting the
Externí odkaz:
https://doaj.org/article/0c76473c5059497ebc79032ea75a2cb8