Výsledky vyhledávání - "4 aminobutyric acid A receptor"

Delayed application of the anesthetic propofol contrasts the neurotoxic effects of kainate on rat organotypic spinal slice cultures

Autor: Dzejla Bajrektarevic, Andrea Nistri

Publikováno v: NeuroToxicology. 54:1-10

Excitotoxicity due to hyperactivation of glutamate receptors is thought to underlie acute spinal injury with subsequent strong deficit in spinal network function. Devising an efficacious protocol of neuroprotection to arrest excitotoxicity might, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0998c016853190d9e46f9a628084d1
https://doi.org/10.1016/j.neuro.2016.03.001

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Meta-analysis of genome-wide association studies on the intolerance of angiotensin-converting enzyme inhibitors

Autor: Mahmoudpour, Seyed H., Veluchamy, Abirami, Siddiqui, Moneeza K., Asselbergs, Folkert W., Souverein, Patrick C., De Keyser, Catherine E., Hofman, Albert, Lang, Chim C., Doney, Alexander S.F., Stricker, Bruno H., De Boer, Anthonius, Maitland-Van Der Zee, Anke H., Palmer, Colin N.A., Pharmacoepidemiology and Clinical Pharmacology, Afd Pharmacoepi & Clinical Pharmacology

Publikováno v: Pharmacogenetics Genomics, 27(3), 112-119. Lippincott Williams & Wilkins
Pharmacogenetics and Genomics, 27(3), 112. Lippincott Williams and Wilkins
Pharmacogenetics and genomics, 27(3), 112-119. Lippincott Williams and Wilkins
Pharmacogenetics and genomics, 27(3), 112. Lippincott Williams and Wilkins

Objectives To identify single nucleotide polymorphisms (SNPs) associated with switching from an angiotensin-converting enzyme (ACE)-inhibitor to an angiotensin receptor blocker. Methods Two cohorts of patients starting ACE-inhibitors were identified

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https://doi.org/10.1097/fpc.0000000000000264

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Abnormal repetitive behaviors in zebrafish and their relevance to human brain disorders

Autor: Zabegalov, K. N., Khatsko, S. L., Lakstygal, A. M., Demin, K. A., Cleal, M., Fontana, B. D., McBride, S. D., Harvey, B. H., de Abreu, M. S., Parker, M. O., Kalueff, A. V.

Publikováno v: Behav. Brain Res.
Behavioural Brain Research

Abnormal repetitive behaviors (ARBs) are a prominent symptom of numerous human brain disorders and are commonly seen in rodent models as well. While rodent studies of ARBs continue to dominate the field, mounting evidence suggests that zebrafish (Dan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______917::fd875a76dd1b5b81d6c9d70b5dc157fb
https://hdl.handle.net/10995/101783

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Inhibition of the GABAA Receptor by Sulfated Neurosteroids: A Mechanistic Comparison Study between Pregnenolone Sulfate and Dehydroepiandrosterone Sulfate

Autor: Amal Kanti Bera, Divya Sachidanandan

Publikováno v: Journal of Molecular Neuroscience. 56:868-877

The ?-aminobutyric acid type A receptor (GABAAR) is negatively modulated by two structurally similar neurosteroids, pregnenolone sulfate (PS) and dehydroepiandrosterone sulfate (DHEAS). This study attempted to ascertain the molecular mechanisms of in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9de75c19dc6be1439ccc0551feec3b1
https://doi.org/10.1007/s12031-015-0527-4

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Advances in Drug Design Based on the Amino Acid Approach: Taurine Analogues for the Treatment of CNS Diseases

Autor: Ednir de Oliveira Vizioli, Man Chin Chung, Jean Leandro dos Santos, Priscila Longhin Bosquesi, Paulo Renato Yamasaki, Pedro Malatesta

Publikováno v: Pharmaceuticals, Vol 5, Iss 10, Pp 1128-1146 (2012)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Pharmaceuticals

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https://doi.org/10.3390/ph5101128

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L-Ornithine attenuates corticotropin-releasing factor-induced stress responses acting at GABA_A receptors in neonatal

Autor: Koji Kurata, M. Aoki, Koji Morishita, Kazutaka Shigemi, D. M. Denbow, Shozo Tomonaga, Mitsuhiro Furuse

Publikováno v: Neuroscience. 172:226-231

I.c.v. injection of L-ornithine has been shown to have sedative and hypnotic effects on neonatal chicks exposed to acute stressful conditions. To clarify the mechanism, we conducted three experiments under strengthened stressful conditions with corti

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http://hdl.handle.net/2324/25435

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Spontaneous Thermal Motion of the GABAA Receptor M2 Channel-lining Segments

Autor: Myles H. Akabas, Amal Kanti Bera

Publikováno v: Journal of Biological Chemistry. 280:35506-35512

The gamma-aminobutyric acid type A (GABA(A)) receptor channel opening involves translational and rotational motions of the five channel-lining, M2 transmembrane segments. The M2 segment's extracellular half is loosely packed and undergoes significant

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https://doi.org/10.1074/jbc.m504645200

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GABAA receptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis

Autor: Cristiana Mollinari, Irene Carunchio, Daniela Merlo, Cristina Zona, Massimo Pieri

Publikováno v: European journal of neuroscience
28 (2008): 1275–1285. doi:10.1111/j.1460-9568.2008.06436.x
info:cnr-pdr/source/autori:Irene Carunchio1,2; Cristiana Mollinari3; Massimo Pieri1,2; Daniela Merlo3,4; Cristina Zona1,2/titolo:GABAA receptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis/doi:10.1111%2Fj.1460-9568.2008.06436.x/rivista:European journal of neuroscience (Print)/anno:2008/pagina_da:1275/pagina_a:1285/intervallo_pagine:1275–1285/volume:28

Amyotrophic lateral sclerosis is a neurodegenerative disease characterized by the selective degeneration of motor neurons in the spinal cord, brainstem and cerebral cortex. In this study we have analysed the electrophysiological properties of GABA(A)

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http://www.cnr.it/prodotto/i/59203

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Possible involvement of supraspinal opioid and GABA receptors in CDP-choline-induced antinociception in acute pain models in rats

Autor: Deniz Bagdas, Emre Hamurtekin, M. Sibel Gurun

Cytidine-5'-diphosphate choline (CDP-choline; citicoline) is an essential endogenous compound normally produced by the organism and is a source of cytidine and choline. Our recent studies on acute pain models demonstrate that intracerebroventricularl

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http://hdl.handle.net/11452/29261

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Would right atrial stretch inhibit sodium intake following GABAA receptor activation in the lateral parabrachial nucleus?

Autor: José Vanderlei Menani, Caroline Gusson Shimoura, S. P. Barbosa, Juliana Irani Fratucci De Gobbi

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

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