Zobrazeno 1 - 10
of 64
pro vyhledávání: '"4]- triazolo[1"'
Autor:
N. I. Krasovska
Publikováno v:
Фармацевтичний журнал, Vol 3, Pp 44-54 (2022)
Despite their high efficacy NSAIDs have significant side effects due to non-selective inhibition of COX-1 and COX-2. Due to this, medical chemists still pay considerable attention to their design and synthesis, in particular the creation of hybrid mo
Externí odkaz:
https://doaj.org/article/99213b63b6f84b3d9953fbbec410d709
Publikováno v:
شیمی کاربردی روز, Vol 17, Iss 62, Pp 169-178 (2022)
In this work, facile and efficient procedures were described for the synthesis of 4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamides via three-component reaction of aryl aldehyde, acetoacetanilide and 3-amino-1,2,4-triazole. The reactions wer
Externí odkaz:
https://doaj.org/article/d71fd868e4e944b8ae04714f09fb6ebe
Autor:
Boshi Huang, Ye Tian, Peng Zhan, Dirk Daelemans, Dongwei Kang, Erik De Clercq, Christophe Pannecouque, Xinyong Liu
Publikováno v:
Chemical Biology & Drug Design. 97:67-76
Taking the previously reported compound BH-7d as the lead, we designed and synthesized a series of piperidinyl-substituted [1,2,4]triazolo[1,5-a]pyrimidines, and their anti-HIV activities as well as cytotoxicities were evaluated. Several compounds ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53aef6531ee5d1fff895b5697bf34d60
https://doi.org/10.1111/cbdd.13760
https://doi.org/10.1111/cbdd.13760
Autor:
Romeo Romagnoli, Paola Oliva, Filippo Prencipe, Stefano Manfredini, Federica Budassi, Andrea Brancale, Salvatore Ferla, Ernest Hamel, Diana Corallo, Sanja Aveic, Lorenzo Manfreda, Elena Mariotto, Roberta Bortolozzi, Giampietro Viola
Publikováno v:
Pharmaceuticals; Volume 15; Issue 8; Pages: 1031
Pharmaceuticals
Pharmaceuticals
A further investigation aiming to generate new potential antitumor agents led us to synthesize a new series of twenty-two compounds characterized by the presence of the 7-(3′,4′,5′-trimethoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidine pharmacophor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c08dcd9c99600c2e0ad2a7d35ddf5c1
https://hdl.handle.net/11577/3474772
https://hdl.handle.net/11577/3474772
Publikováno v:
Molecules, Vol 13, Iss 7, Pp 1501-1517 (2008)
Hydrazonyl bromides 2a,b reacted with active methylene compounds (dibenzoylmethane, acetylacetone, ethyl acetoacetate, phenacyl cyanide, acetoacetanilide, ethyl cyanoacetate, cyanoacetamide and malononitrile) to afford the corresponding 1,3,4,5- tetr
Externí odkaz:
https://doaj.org/article/b45b488de1ad4bb591d8414348550f47
Publikováno v:
Molecules, Vol 12, Iss 5, Pp 1136-1146 (2007)
A series of novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives has been designed and synthesized in order to find novel anti-tumor compounds. The structures of all the compounds were confirmed by IR, 1H-NMR, MS and elemental analysis. Their anti-tumo
Externí odkaz:
https://doaj.org/article/7169f695ae644bad85d331e45c65093e
Autor:
Milan Potacek, Jiri Verner
Publikováno v:
Molecules, Vol 11, Iss 1, Pp 34-42 (2006)
The reactivity of alicyclic ketazines in criss-cross cycloadditions was investigated. They react with potassium cyanate and ammonium thiocyanate in the presence of acetic acid to form spirocyclic perhydro[1,2,4]triazolo[1,2-a][1,2,4]triazole-1,5-dion
Externí odkaz:
https://doaj.org/article/22ac0db29ecc429698ca6bd14786334e
Akademický článek
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Publikováno v:
Molecules, Vol 6, Iss 6, Pp 519-527 (2001)
A variety of novel [1,2,4]triazolo[1,5-c]pyrimidine-13-ones (4a-f) and (5b-d) could be obtained via reaction of 9-amino-7-(4’-chlorophenyl)-8,9-dihydro-8-imino-6H,7H-[1]benzopyrano[3`,4`:5,6]pyrano[2,3-d]pyrimidine-6-one (3) with a varie
Externí odkaz:
https://doaj.org/article/07aac133da9d4fb68017c1f7d01b8a0c
Publikováno v:
Molbank, Vol 2006, Iss 3, p M476 (2006)
n/a
Externí odkaz:
https://doaj.org/article/070e50b6ac0b405d8944a7bacf958d47