Výsledky vyhledávání - "3CLpro main protease"

Akademický článek

TAT-peptide conjugated repurposing drug against SARS-CoV-2 main protease (3CLpro): Potential therapeutic intervention to combat COVID-19

Autor: Mohammad Azam Ansari, Qazi Mohammad Sajid Jamal, Suriya Rehman, Ahmad Almatroudi, Mohammad A. Alzohairy, Mohammad N. Alomary, Takshashila Tripathi, Ali H. Alharbi, Syed Farooq Adil, Mujeeb Khan, M. Shaheer Malik

Publikováno v: Arabian Journal of Chemistry, Vol 13, Iss 11, Pp 8069-8079 (2020)

The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that originated in Chinese city of Wuhan has caused around 906,092 deaths and 28,040,853 confirmed cases worldwide (https://covid19.who.int/, 11 September 2020). In a life-threatening s

Externí odkaz: https://doaj.org/article/a818732e7fa74532a436ee04fc3aa910

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Akademický článek

Design, Synthesis and Evaluation of Fused Bicyclo[2.2.2]octene as a Potential Core Scaffold for the Non-Covalent Inhibitors of SARS-CoV-2 3CLpro Main Protease

Autor: Barbara Herlah, Andrej Hoivik, Luka Jamšek, Katja Valjavec, Norio Yamamoto, Tyuji Hoshino, Krištof Kranjc, Andrej Perdih

Publikováno v: Pharmaceuticals, Vol 15, Iss 5, p 539 (2022)

The emergence of SARS-CoV-2, responsible for the global COVID-19 pandemic, requires the rapid development of novel antiviral drugs that would contribute to an effective treatment alongside vaccines. Drug repurposing and development of new molecules t

Externí odkaz: https://doaj.org/article/8d0e56a5c12d46d488d1637e278c88c0

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In silico evaluation of antiviral activity of flavone derivatives and commercial drugs against SARS-CoV-2 main protease (3CLpro)

Autor: R. Abidi, B. Bouammli, L. El Farh, M. Merzouki, A. Challioui, L. Bourassi

In this paper the in silco evaluation of the antiviaral activity against the current spread of severe acute respiratory syndrome novel coronavirus 2 (SARS-CoV-2) of several anti-viral components such as Chloroquine, Simeprevir, Lopinavir and a series

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e4cbdb65229fdb97872efc7ded34f300

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TAT-peptide conjugated repurposing drug against SARS-CoV-2 main protease (3CLpro): Potential therapeutic intervention to combat COVID-19

Autor: Mujeeb Khan, Mohammad N. Alomary, Syed Farooq Adil, Mohammad Azam Ansari, Ali H. Alharbi, Takshashila Tripathi, Mohammad A. Alzohairy, Ahmad Almatroudi, Qazi Mohammad Sajid Jamal, M. Shaheer Malik, Suriya Rehman

Publikováno v: Arabian Journal of Chemistry
Arabian Journal of Chemistry, Vol 13, Iss 11, Pp 8069-8079 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8f619c873b34e34925a608bd772ba1
https://doi.org/10.1016/j.arabjc.2020.09.037

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Akademický článek

Optimization of quenched fluorescent peptide substrates of SARS-CoV-2 3CL ^pro main protease (Mpro) from proteomic identification of P6-P6' active site specificity.

Autor: Cesar Ramos de Jesus H; Centre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Solis N; Centre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Machado Y; Centre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Pablos I; Centre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Bell PA; Centre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Kappelhoff R; Centre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Grin PM; Centre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Sorgi CA; Centre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, British Columbia, Canada.; Department of Chemistry, Faculty of Philosophy, Sciences and Letters at Ribeirão Preto, University of São Paulo, São Paulo, Brazil., Butler GS; Centre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Overall CM; Centre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, British Columbia, Canada.; Yonsei Frontier Lab, Yonsei University, Seoul, Republic of Korea.

Publikováno v: Journal of virology [J Virol] 2024 Jun 13; Vol. 98 (6), pp. e0004924. Date of Electronic Publication: 2024 May 14.

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