Zobrazeno 1 - 10
of 11
pro vyhledávání: '"3208 Medical Physiology"'
Autor:
Lakeland, Thomas
Nicotinamide adenine dinucleotide (NAD), an archetypal cellular energy carrier, is vital to good health but declines with ageing and with metabolic disease. Restoration of declining NAD levels—achieved through diet, exercise, and pharmaceutical int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43b0854077441f90a3f2ecf79d90fd51
Publikováno v:
Current Opinion in Physiology. 17:9-16
Inositol 1,4,5-trisphosphate receptors (IP3Rs) are intracellular Ca2+ channels. They allow cell-surface receptors that stimulate IP3 formation to evoke rapid Ca2+ release from the endoplasmic reticulum (ER). IP3Rs initiate local and global cytosolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8848a6dd5100188ab8c0519c2a8c9c
https://doi.org/10.1016/j.cophys.2020.06.002
https://doi.org/10.1016/j.cophys.2020.06.002
Autor:
Das, Abhijit
The homeostatic regulation of amino acid concentrations is crucial for optimal brain function and development. Different amino acid transporters at cell membranes work together to facilitate the movement of amino acids into and out of the brain. Desp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21e1c04c81399d8df63860716626c594
Nanoscale molecular architecture controls calcium diffusion and ER replenishment in dendritic spines
Autor:
David Mazaud, Alexis Bemelmans, Lilia Kushnireva, David Holcman, Kanishka Basnayake, Nathalie Rouach, Eduard Korkotian
Publikováno v:
Science Advances
Science Advances, American Association for the Advancement of Science (AAAS), 2021, 7 (38), ⟨10.1126/sciadv.abh1376⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2021, 7 (38), ⟨10.1126/sciadv.abh1376⟩
Dendritic spines are critical components of neuronal synapses as they receive and transform synaptic inputs into a succession of calcium-regulated biochemical events. The spine apparatus (SA), an extension of smooth endoplasmic reticulum, regulates s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3335daeaa50771d97c5333c970ab0eab
Autor:
Vladyslav V. Vyazovskiy, A J Morton
When the idea of this issue was first conceived the two obvious questions were, whether or not we really need any more reviews on sleep and if there had been enough advances in the past couple of years to merit a whole new issue on sleep. We thought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10a51e3f6d893b034518e5be6dde2a3
https://ora.ox.ac.uk/objects/uuid:4cf0767c-a023-4280-8714-1e4e796b1c33
https://ora.ox.ac.uk/objects/uuid:4cf0767c-a023-4280-8714-1e4e796b1c33
Autor:
Frezza, Christian
Publikováno v:
Nat Metab
Exposure to high glucose under inflammatory conditions is detrimental to insulin secreting beta cells in the pancreas. Fu and colleagues, describe a metabolic axis that reduces the production of the danger molecule nitric oxide and improves survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc003042642c19a638c6594fc62b0e5
https://europepmc.org/articles/PMC7115866/
https://europepmc.org/articles/PMC7115866/
Autor:
Timothy O'Leary
Publikováno v:
Current Opinion in Physiology
Most neurons express a wide variety of ion channels with diverse properties, providing a rich toolbox for tuning neural function. Coexpressed channel types are often degenerate: they share overlapping roles in shaping electrophysiological properties.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5083e0bc18b0f212b273832ff001d7e
https://doi.org/10.1016/j.cophys.2018.01.006
https://doi.org/10.1016/j.cophys.2018.01.006
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
The cellular membrane is very heterogenous and enriched with high-density regions forming microdomains, as revealed by single particle tracking experiments. However the organization of these regions remain unexplained. We determine here the biophysic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbee4d1c8f19064796396f0da50ff1ac
https://www.repository.cam.ac.uk/handle/1810/314963
https://www.repository.cam.ac.uk/handle/1810/314963
Autor:
Huang, CL
Roger Yonchien Tsien (1952-2016; Elected ForMemRS 2006) displayed precocious childhood talents in chemistry. After graduating from Harvard University in chemistry and physics in 1972, he pursued a PhD programme in the Physiological Laboratory, Cambri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d328a5b6e3f8f77c6962a1daaf46d075