Zobrazeno 1 - 10 of 3 233 pro vyhledávání: '"3121 General medicine, internal medicine and other clinical medicine"'
1
Virtual communication is commonly used in Finnish interstitial lung disease multidisciplinary meetings
Autor: Johanna Salonen, Hanna Nurmi, Ulla Hodgson, Hannele Hasala, Maritta Kilpeläinen, Maria Hollmen, Minna Purokivi, Riitta Kaarteenaho
Multidisciplinary meeting (MDM) is a core element in the diagnosis of interstitial lung diseases (ILD). The aim of the study was to investigate the implementation and key elements related to ILD MDMs in Finnish specialized care, which is characterize
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759ce3a4b0bc8e2867dd692e6740c93e
http://hdl.handle.net/10138/356970
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2
The angiopoietin receptor Tie2 is atheroprotective in arterial endothelium
Autor: Andrey Anisimov, Shentong Fang, Karthik Amudhala Hemanthakumar, Tiit Örd, Kristof van Avondt, Raphael Chevre, Anu Toropainen, Prosanta Singha, Huda Gilani, Su D. Nguyen, Sinem Karaman, Emilia A. Korhonen, Ralf H. Adams, Hellmut G. Augustin, Katariina Öörni, Oliver Soehnlein, Minna U. Kaikkonen, Kari Alitalo
Publikováno v: Nature Cardiovascular Research. 2:307-321
Leukocytes and resident cells in the arterial wall contribute to atherosclerosis, especially at sites of disturbed blood flow. Expression of endothelial Tie1 receptor tyrosine kinase is enhanced at these sites, and attenuation of its expression reduc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa11707359131185bee4b27b0aa7ffc
https://doi.org/10.1038/s44161-023-00224-y
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5
Optimal sampling and analysis methods for clinical diagnostics of vaginal microbiome
Autor: Katja Kero, Niina Hieta, Teemu Kallonen, Anne Ahtikoski, Hanna K. Laine, Jaana Rautava, Eveliina Munukka
Publikováno v: European Journal of Clinical Microbiology & Infectious Diseases. 42:201-208
Next-generation sequencing-based microbiological analysis is a complex way to profile vaginal microbiome samples since each step affects the results gained. Methodologies for sample collection lack golden standards. We compared Puritan DNA/RNA swab (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ab6d7b1df497a46d22fb3afbcbb599
https://doi.org/10.1007/s10096-022-04545-x
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6
Associations of polygenic risk scores for preeclampsia and blood pressure with hypertensive disorders of pregnancy
Autor: Jouko Nurkkala, Anni Kauko, null FinnGen, Hannele Laivuori, Tanja Saarela, Jaakko S. Tyrmi, Felix Vaura, Susan Cheng, Natalie A. Bello, Jenni Aittokallio, Teemu Niiranen
Publikováno v: Journal of Hypertension. 41:380-387
Background:Preexisting hypertension increases risk for preeclampsia. We examined whether a generic blood pressure polygenic risk score (BP-PRS), compared with a preeclampsia-specific polygenic risk score (PE-PRS), could better predict hypertensive di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2a0a9b96fb0bbf2312d11de10a4b37
https://doi.org/10.1097/hjh.0000000000003336
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7
Moderate hyperuricaemia ameliorated kidney damage in a low‐renin model of experimental renal insufficiency
Autor: Venla Kurra, Arttu Eräranta, Timo Paavonen, Teemu Honkanen, Juhani Myllymäki, Asko Riutta, Ilkka Tikkanen, Päivi Lakkisto, Jukka Mustonen, Ilkka Pörsti
Publikováno v: Basic & Clinical Pharmacology & Toxicology. 132:21-32
Background: Hyperuricemia may predispose to renal damage, but in end-stage renal disease lower uric acid concentrations have been associated with higher mortality. In experimental studies, uric acid has promoted renal fibrosis and inflammation, but s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8304ffc312ca611f36f37041800676
https://doi.org/10.1111/bcpt.13806
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8
Ultrasound-Guided Versus Conventional MANTA Vascular Closure Device Deployment After Transcatheter Aortic Valve Implantation
Autor: Hirokazu Miyashita, Noriaki Moriyama, Sebastian Dahlbacka, Tommi Vähäsilta, Tiina Vainikka, Mikko Jalanko, Juho Viikilä, Mika Laine
Publikováno v: The American Journal of Cardiology. 180:116-123
Publisher Copyright: © 2022 The Authors Despite the development of device technology and operators' experience, access site vascular complications (VCs) remain one of the major concerns after transcatheter aortic valve implantation (TAVI). MANTA (Te
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ee7349c4173f68c77dd2557c10cf04
https://doi.org/10.1016/j.amjcard.2022.06.046
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9
Astrocyte Progenitors Derived From Patients With Alzheimer Disease Do Not Impair Stroke Recovery in Mice
Autor: Nelli-Noora Välimäki, Abdulhameed Bakreen, Sara Häkli, Hiramani Dhungana, Meike H. Keuters, Yannick Dunlop, Marja Koskuvi, Velta Keksa-Goldsteine, Minna Oksanen, Henna Jäntti, Šárka Lehtonen, Tarja Malm, Jari Koistinaho, Jukka Jolkkonen
Publikováno v: Stroke. 53:3192-3201
Background: Species-specific differences in astrocytes and their Alzheimer disease-associated pathology may influence cellular responses to other insults. Herein, human glial chimeric mice were generated to evaluate how Alzheimer disease predisposing
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3030cbc40910164bf83f0cc2c828baa
https://doi.org/10.1161/strokeaha.122.039700
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