Zobrazeno 1 - 8
of 8
pro vyhledávání: '"3-hydroxyquinidine"'
Autor:
J. Lind, S.W. Mascarella, R. A. Wohl, Frank I. Carroll, Philip Abraham, K. D. Gaetano, K. Petzoldt
Publikováno v:
ChemInform. 23
Publikováno v:
DICP : the annals of pharmacotherapy. 25(7-8)
Publikováno v:
British journal of clinical pharmacology. 26(4)
1. The pharmacokinetics and pharmacodynamics of quinidine and 3-hydroxyquinidine based upon measurements of total and unbound serum concentrations were determined after a single dose (400 mg) and at steady state (200 mg every 6 h). 2. The oral cleara
Publikováno v:
Clinical pharmacology and therapeutics. 27(1)
In the sera from 42 patients receiving quinidine, (3S)-3-hydroxyquinidine (3-OH), an active metabolite of quinidine, and quinidine were determined by high-pressure liquid chromatography with fluorescence detection. These results were added to those o
Publikováno v:
American heart journal. 113(2 Pt 1)
Recent reports indicate that the metabolite of quinidine, 3-hydroxyquinidine, is pharmacologically active. It was the primary purpose of this study to determine total and unbound concentrations of quinidine and 3-hydroxyquinidine in 25 patients recei
Publikováno v:
Therapeutic drug monitoring. 7(3)
Autor:
Ferenc Follath, Gilbert R. Kaufmann, Samuel Vozeh, Huy-Riem Ha, Margrit Bindschedler, Theodor W. Guentert
Publikováno v:
The American journal of cardiology. 59(6)
The relation between serum concentration of 3-hydroxyquinidine (3-OHQ), a major metabolite of quinidine in humans, and the pharmacologic effect alone and in combination with the parent drug was studied. The heart rate-corrected, computer-averaged QT
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