Zobrazeno 1 - 10
of 760
pro vyhledávání: '"3-Hydroxykynurenine"'
Autor:
Maja Tomczyk, Monika Bidzan-Wiącek, Jakub Antoni Kortas, Magdalena Kochanowicz, Zbigniew Jost, Helena L. Fisk, Philip C. Calder, Jędrzej Antosiewicz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The effects of long-term omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation during endurance training on tryptophan (Trp) metabolism and mental state of healthy individuals have not been evaluated so far. Concentrations of plasma
Externí odkaz:
https://doaj.org/article/484af875563f4a9eae888b19ef100b2b
Autor:
Arduino A. Mangoni, Angelo Zinellu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
There is an increasing interest in the pathophysiological role of the kynurenine pathway of tryptophan metabolism in the regulation of immune function and inflammation. We sought to address the link between this pathway and the presence rheumatic dis
Externí odkaz:
https://doaj.org/article/0a63d825060542ddbeafe3ffafc83fc4
Akademický článek
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Autor:
Kamila Kozieł, Ewa M. Urbanska
Publikováno v:
Cells, Vol 12, Iss 3, p 460 (2023)
The tryptophan–kynurenine pathway (Trp–KYN) is the major route for tryptophan conversion in the brain and in the periphery. Kynurenines display a wide range of biological actions (which are often contrasting) such as cytotoxic/cytoprotective, oxi
Externí odkaz:
https://doaj.org/article/f6be6e1a45904faeae7a14583f166def
Autor:
Aleksandr V. Zhuravlev, Polina N. Ivanova, Ksenia A. Makaveeva, Gennadii A. Zakharov, Ekaterina A. Nikitina, Elena V. Savvateeva-Popova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12356 (2022)
Being involved in development of Huntington’s, Parkinson’s and Alzheimer’s diseases, kynurenine pathway (KP) of tryptophan metabolism plays a significant role in modulation of neuropathology. Accumulation of a prooxidant 3-hydroxykynurenine (3-
Externí odkaz:
https://doaj.org/article/2c9c48e0f08f4d11bb4cefc9e67bc787
Publikováno v:
Molecules, Vol 27, Iss 15, p 4929 (2022)
A specific mosquito enzyme, 3-hydroxykynurenine transaminase (HKT), is involved in the processing of toxic metabolic intermediates of the tryptophan metabolic pathway. The HKT enzymatic product, xanthurenic acid, is required for Plasmodium spp. devel
Externí odkaz:
https://doaj.org/article/583a36c225514aa9b600b256ff71cb08
Publikováno v:
Metabolites, Vol 12, Iss 6, p 492 (2022)
We examined the relationships of tryptophan (Trp) and the metabolites of the kynurenine pathway (KP) to the occurrence of type 2 diabetes (T2D) and metabolic risk factors in obese middle-aged women. The study included 128 obese women divided into two
Externí odkaz:
https://doaj.org/article/43e39436a8504ffca91c23f7caa1684c
Autor:
Kirsten Berding, Thomaz F. S. Bastiaanssen, Gerard M. Moloney, Serena Boscaini, Conall R. Strain, Andrea Anesi, Caitriona Long-Smith, Fulvio Mattivi, Catherine Stanton, Gerard Clarke, Timothy G. Dinan, John F. Cryan
The impact of diet on the microbiota composition and the role of diet in supporting optimal mental health have received much attention in the last decade. However, whether whole dietary approaches can exert psychobiotic effects is largely understudie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4dd0382369db601cc7a058910cf266
https://hdl.handle.net/10449/77115
https://hdl.handle.net/10449/77115
Akademický článek
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Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Dysfunctions of kynurenine pathway of tryptophan metabolism (KPTM) are associated with multiple neuropathologies in vertebrates and invertebrates. Drosophila mutants with altered content of kynurenines are model objects for studying the molecular pro
Externí odkaz:
https://doaj.org/article/64b2c2daf4bd4f0289eadaa8483abe74