Zobrazeno 1 - 10
of 629
pro vyhledávání: '"3-Bromopyruvate"'
Autor:
Hussam H. Baghdadi
Publikováno v:
SVU - International Journal of Medical Sciences, Vol 7, Iss 2, Pp 429-437 (2024)
Background: Grade IV astrocytoma, or glioblastoma multiforme (GBM), is among the most commonly aggressive gliomas resistant to treatment approaches. There is a high expression of glycolytic genes in clinical glioblastoma patients that was reported to
Externí odkaz:
https://doaj.org/article/c15dd97a5e1143928844e809415ad51a
Autor:
Salah Mohamed El Sayed
Publikováno v:
SVU - International Journal of Medical Sciences, Vol 7, Iss 2, Pp 223-231 (2024)
Background: Pyruvate (an antioxidant) result from aerobic glucose oxidation (aerobic glycolysis) while lactate (a pro-oxidant metabolite in the tumor microenvironment) results from anaerobic glycolysis. Lactate is a structural analog to pyruvate (for
Externí odkaz:
https://doaj.org/article/6d7963415c3e415aa4767422862bf20a
Publikováno v:
Clinical, Cosmetic and Investigational Dermatology, Vol Volume 16, Pp 3229-3239 (2023)
Le Zhuang,1 Weiyuan Ma,2 Jing Jiao1 1Department of Dermatology, Central Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, People’s Republic of China; 2Department of Dermatology, Affiliated Hospital of Weifang Medic
Externí odkaz:
https://doaj.org/article/d9d79560fac74501a8da06b334cfe325
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Metabolic reprogramming in cancer cells plays a crucial role in cancer development, metastasis and invasion. Cancer cells have a unique metabolism profile that could switch between glycolysis and oxidative phosphorylation (OXPHOS) in order t
Externí odkaz:
https://doaj.org/article/bf0081028d2e46248da62a4e2a9fe0d1
Autor:
Yiman He, Huawan Chen, Wenbo Li, Lu Xu, Huan Yao, Yang Cao, Zhigang Wang, Liang Zhang, Dong Wang, Di Zhou
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Radiotherapy (RT) is one of the most mainstream cancer therapeutic modalities. However, due to the lack of specificity of the radiation adopted, both normal and cancerous cells are destroyed indiscriminately. This highlights the c
Externí odkaz:
https://doaj.org/article/ec4f9caf9a07464cbb1cd71e5843cc12
Akademický článek
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Akademický článek
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Autor:
Jiexin Wen, Yong Luo, Hui Gao, Liang Zhang, Xiang Wang, Ju Huang, Tingting Shang, Di Zhou, Dong Wang, Zhigang Wang, Pan Li, Zhaoxia Wang
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-22 (2021)
Abstract Background Photodynamic therapy (PDT) is a promising therapeutic modality that can convert oxygen into cytotoxic reactive oxygen species (ROS) via photosensitizers to halt tumor growth. However, hypoxia and the unsatisfactory accumulation of
Externí odkaz:
https://doaj.org/article/388d28976a174fa3867edfa488680262
Autor:
Irini Skaripa-Koukelli, David Hauton, John Walsby-Tickle, Eloïse Thomas, Joshua Owen, Abirami Lakshminarayanan, Sarah Able, James McCullagh, Robert C. Carlisle, Katherine A. Vallis
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Background Triple negative breast cancer (TNBC) poses a serious clinical challenge as it is an aggressive form of the disease that lacks estrogen receptor, progesterone receptor, and ERBB2 (formerly HER2) gene amplification, which limits the
Externí odkaz:
https://doaj.org/article/4d4325a9ec3e474a9fcea62064992e58
Autor:
Hojatolla Nikravesh, Mohammad Javad Khodayar, Babak Behmanesh, Masoud Mahdavinia, Ali Teimoori, Soheila Alboghobeish, Leila Zeidooni
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background 5-Fluorouracil (5-FU) is regarded as the first line treatment for colorectal cancer; however, its effectiveness is limited by drug resistance. The ultimate goal of cancer therapy is induction of cancer cell death to achieve an eff
Externí odkaz:
https://doaj.org/article/3681412f5f1a4cf89ee02ca2b9401d41