Radiosynthesis and Preclinical Evaluation of 11C-VA426, a Cyclooxygenase-2 Selective Ligand

Autor: Assunta Carpinelli 1, 2, Paolo Rainone 2, 3 Sara Belloli 1, Annalisa Reale 4, Andrea Cappelli 4, Giuliani Germano 4, Valentina Murtaj 1, 5, Angela Coliva 2 Giuseppe Di Grigoli 1, Angela Valeri 4, Maria Carla Gilardi 1, Luigi Gianolli 2, Maurizio Anzini 4, Rosa Maria Moresco 1, 6

Publikováno v: Contrast media & molecular imaging 2019 (2019): 5823261–13. doi:10.1155/2019/5823261.
info:cnr-pdr/source/autori:Assunta Carpinelli 1,2, Paolo Rainone 2,3 Sara Belloli 1,2, Annalisa Reale 4, Andrea Cappelli 4, Giuliani Germano 4, Valentina Murtaj 1,2,5, Angela Coliva 2 Giuseppe Di Grigoli 1,2, Angela Valeri 4, Maria Carla Gilardi 1, Luigi Gianolli 2, Maurizio Anzini 4 and Rosa Maria Moresco 1,2,6/titolo:Radiosynthesis and Preclinical Evaluation of 11C-VA426, a Cyclooxygenase-2 Selective Ligand/doi:10.1155%2F2019%2F5823261./rivista:Contrast media & molecular imaging/anno:2019/pagina_da:5823261/pagina_a:13/intervallo_pagine:5823261–13/volume:2019

Cyclooxygenase-2 (COX-2) is involved in the inflammatory response, and its recurrent overexpression in cancers as well as in neurodegenerative disorders has made it an important target for therapy. For this reason, noninvasive imaging of COX-2 expres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::a2e10f6605c074fd7829dfd4b1a5ca70
http://www.cnr.it/prodotto/i/407685