Výsledky vyhledávání - "2D cell cultures"

Akademický článek

Cigarette Smoke-Induced Epithelial-to-Mesenchymal Transition: Insights into Cellular Mechanisms and Signaling Pathways

Autor: Sarah Mohammed Alqithami, Amrita Machwe, David K. Orren

Publikováno v: Cells, Vol 13, Iss 17, p 1453 (2024)

This review delves into the molecular complexities underpinning the epithelial-to-mesenchymal transition (EMT) induced by cigarette smoke (CS) in human bronchial epithelial cells (HBECs). The complex interplay of pathways, including those related to

Externí odkaz: https://doaj.org/article/c56c9477fa734239bce183d3827ee32f

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Akademický článek

Spheroids as 3D Cell Models for Testing of Drugs

Autor: Nováková E., Mikušová V., Šupolíková M.

Publikováno v: European Pharmaceutical Journal, Vol 70, Iss s1, Pp 37-43 (2023)

Cell lines are an important tool for scientific research and clinical and pharmaceutical applications. Cells are isolated from animal tissues and can be expanded in culture to study cell biology and disease. The isolated cells can be used to produce

Externí odkaz: https://doaj.org/article/080c5e4841934445803dcb1c7d26f186

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Akademický článek

Celecoxib, a Non-Steroidal Anti-Inflammatory Drug, Exerts a Toxic Effect on Human Melanoma Cells Grown as 2D and 3D Cell Cultures

Autor: Alessandro Venuta, Rosarita Nasso, Armando Gisonna, Roberta Iuliano, Sara Montesarchio, Vittoria Acampora, Leandra Sepe, Angelica Avagliano, Rosaria Arcone, Alessandro Arcucci, Maria Rosaria Ruocco

Publikováno v: Life, Vol 13, Iss 4, p 1067 (2023)

Cutaneous melanoma (CM) remains one of the leading causes of tumor mortality due to its high metastatic spread. CM growth is influenced by inflammation regulated by prostaglandins (PGs) whose synthesis is catalyzed by cyclooxygenases (COXs). COX inhi

Externí odkaz: https://doaj.org/article/990595e297da422bb990022d2f442b43

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Akademický článek

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Recent advances on cell culture platforms for In vitro drug screening and cell therapies: from conventional to microfluidic strategies

Autor: Cardoso, Beatriz D., Castanheira, Elisabete M. S., Lanceros-Méndez, S., Cardoso, Vanessa Fernandes

The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical research based on biologically accurate screening approaches. Since establishing the 2D in vitro cell culture method, the scientific community has improved cell-ba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______307::5d8d779ae4651636f1b8210bbc2c9b84
https://hdl.handle.net/1822/83701

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Akademický článek

Stable Isotope-Resolved Metabolomics Shows Metabolic Resistance to Anti-Cancer Selenite in 3D Spheroids versus 2D Cell Cultures

Autor: Teresa W.-M. Fan, Salim S. El-Amouri, Jessica K. A. Macedo, Qing Jun Wang, Huan Song, Teresa Cassel, Andrew N. Lane

Publikováno v: Metabolites, Vol 8, Iss 3, p 40 (2018)

Conventional two-dimensional (2D) cell cultures are grown on rigid plastic substrates with unrealistic concentration gradients of O2, nutrients, and treatment agents. More importantly, 2D cultures lack cell–cell and cell–extracellular matrix (ECM

Externí odkaz: https://doaj.org/article/423d8fb11f284b058faf2cc11b54d1b1

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Comparative study of the therapeutic effect of Doxorubicin and Resveratrol combination on 2D and 3D (spheroids) cell culture models

Autor: Duarte de Melo-Diogo, Ilídio J. Correia, Ana S. Nunes, Elisabete C. Costa, Andreia S. Barros

Publikováno v: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP

The assessment of drug-combinations for pancreatic cancer treatment is usually performed in 2D cell cultures. In this study, the therapeutic effect and the synergistic potential of a particular drug-combination towards 2D and 3D cell cultures of panc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85fd3dd5c15b6ba4552badbda496d88f
https://doi.org/10.1016/j.ijpharm.2018.09.016

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Stable Isotope-Resolved Metabolomics Shows Metabolic Resistance to Anti-Cancer Selenite in 3D Spheroids versus 2D Cell Cultures

Autor: Salim S. El-Amouri, Teresa Cassel, Andrew N. Lane, Huan Song, Teresa W.-M. Fan, Jessica K. A. Macedo, Qing Jun Wang

Publikováno v: Metabolites, Vol 8, Iss 3, p 40 (2018)
Metabolites
Volume 8
Issue 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d322813fc118a6c7c958386942be56ae
http://www.mdpi.com/2218-1989/8/3/40

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