Improved anti-cancer effect of epidermal growth factor-gold nanoparticle conjugates by protein orientation through site-specific mutagenesis

Autor: Jun Nakanishi, Aiwen Zhang

Publikováno v: Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 616-626 (2021)
Science and Technology of Advanced Materials
article-version (VoR) Version of Record

Epidermal growth factor (EGF)-nanoparticle conjugates have the potential for cancer therapeutics due to the unique cytotoxic activity in cancer cells with EGF receptor (EGFR) overexpression. To gain its maximum activity, the EGF molecule should be im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db025d7373ac5e3cac96bf9fae1633bf
https://doaj.org/article/ff01d888ae934a829c3bbc3778036aee

Tumor growth suppression by implantation of an anti-CD25 antibody-immobilized material near the tumor via regulatory T cell capture

Autor: Rino Tokunaga, Naoko Nakamura, Tsuyoshi Kimura, Akio Kishida, Yoshihide Hashimoto

Publikováno v: Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 607-615 (2021)
Science and Technology of Advanced Materials
article-version (VoR) Version of Record

In this study, we designed and synthesized an implantable anti-CD25 antibody-immobilized polyethylene (CD25-PE) mesh to suppress tumor growth by removing regulatory T cells (Tregs). The PE mesh was graft-polymerized with poly(acrylic acid), and the a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fd5375be50f33a161f4f29539c61dc
https://doi.org/10.1080/14686996.2021.1944782

Magnetic stimulation of the angiogenic potential of mesenchymal stromal cells in vascular tissue engineering

Autor: Frederico Castelo Ferreira, Carla A.M. Portugal, Joaquim M. S. Cabral, Ana C. Manjua

Publikováno v: Science and Technology of Advanced Materials
article-version (VoR) Version of Record
Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 461-480 (2021)

The growing prevalence of vascular diseases worldwide has emphasized the need for novel tissue-engineered options concerning the development of vascularized 3D constructs. This study reports, for the first time, the use of external magnetic fields to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3711717c93338352d0778c4d86ee873
http://europepmc.org/articles/PMC8245073

Flexible wearable sensors - an update in view of touch-sensing

Autor: Sang Jin Kim, Chi Cuong Vu, Jooyong Kim

Publikováno v: Science and Technology of Advanced Materials
article-version (VoR) Version of Record
Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 26-36 (2021)

Nowadays, much of user interface is based on touch and the touch sensors have been common for displays, Internet of things (IoT) projects, or robotics. They can be found in lamps, touch screens of smartphones, or other wide arrays of applications as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31b7df805596cf01d36d2f2cb1511b1
http://europepmc.org/articles/PMC8018418

Osteoclast and osteoblast responsive carbonate apatite coatings for biodegradable magnesium alloys

Autor: Takaya Akashi, Hideki Katayama, Naomi Noda, Sachiko Hiromoto, Tomohiko Yamazaki, Sayaka Itoh

Publikováno v: Science and Technology of Advanced Materials, Vol 21, Iss 1, Pp 346-358 (2020)
Science and Technology of Advanced Materials
article-version (VoR) Version of Record

Corrosion-control coatings which can enhance bone formation and be completely replaced by bone are attractive for biodegradable Mg alloys. Carbonate apatite (CAp) and hydroxyapatite (HAp) coatings were formed on Mg-4 wt% Y-3 wt% rare earth (WE43) all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b709362504deeb836fdbe21dcad3fc32
https://doi.org/10.1080/14686996.2020.1761237