Zobrazeno 1 - 10
of 13
pro vyhledávání: '"2020 CMBE Young Innovators issue"'
Autor:
Jordan J. Green, Stephany Y. Tzeng, Rakeeb Kureshi, Leilani R. Astrab, Jikui Shen, Paul R. Sargunas, Peter A. Campochiaro, Angela Zhu, Jamie B. Spangler
Publikováno v:
Cell Mol Bioeng
BACKGROUND: Ocular neovascularization is a hallmark of retinal diseases including neovascular age-related macular degeneration and diabetic retinopathy, two leading causes of blindness in adults. Neovascularization is driven by the interaction of sol
Autor:
Ryan A. Koppes, Will Lake, Abigail N. Koppes, Shashi K. Murthy, David T. Breault, Eric Stas, Sanjin Hosic
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: The intestinal epithelium contains specialized cells including enterocytes, goblet, Paneth, enteroendocrine, and stem cells. Impaired barrier integrity in Inflammatory Bowel Disease is characterized by elevated levels of pro-inflammator
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: Fibrin scaffolds are often utilized to treat chronic wounds. The monomer fibrinogen used to create such scaffolds is typically derived from adult human or porcine plasma. However, our previous studies have identified extensive differenc
Publikováno v:
Cellular and Molecular Bioengineering
Introduction Lipid based nanoparticles (LNPs) are clinically successful vectors for hepatic delivery of nucleic acids. These systems are being developed for non-hepatic delivery of mRNA for the treatment of diseases like cystic fibrosis or retinal de
Publikováno v:
Cell Mol Bioeng
Autor:
Bhasirie Thuamsang, Jamal S. Lewis, Rapeepat Sangsuwan, Riley Allen, Svetlana Miakicheva, Noah Pacifici, Hyunsoo Han
Publikováno v:
Cell Mol Bioeng
Cellular and molecular bioengineering, vol 13, iss 5
Cellular and molecular bioengineering, vol 13, iss 5
INTRODUCTION: Lactate secreted by tumors is not just a byproduct, but rather an active modulator of immune cells. There are few studies aimed at investigating the true effect of lactate, which is normally confounded by pH. Such a knowledge gap needs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1df687f3a11cd601152e42707a95cd3
https://europepmc.org/articles/PMC7596145/
https://europepmc.org/articles/PMC7596145/
Autor:
Yasir Suhail, Rena Bizios, Cynthia A Perez, Yi Chen, Christopher R. Rathbone, Allison C. Rhea, Teja Guda, Solaleh Miar, Kshitiz, Joo L. Ong, Elysa Jui, Francisca M. Acosta, Gennifer Chiou, Aparna Gorthi
Publikováno v:
Cell Mol Bioeng
BACKGROUND: Volumetric tissue-engineered constructs are limited in development due to the dependence on well-formed vascular networks. Scaffold pore size and the mechanical properties of the matrix dictates cell attachment, proliferation and successi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce64846572ca074ce1fb099f5e608f0
https://europepmc.org/articles/PMC7596170/
https://europepmc.org/articles/PMC7596170/
Autor:
Katherine M. Aird, Matthew R. Aronson, Jacob A. Halle, Rose A. Gogal, Andrew W. Simonson, Scott H. Medina, Adam B. Glick, Erika S. Dahl
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: Bacteria and cancer cells share a common trait—both possess an electronegative surface that distinguishes them from healthy mammalian counterparts. This opens opportunities to repurpose antimicrobial peptides (AMPs), which are cationi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1d0253160446bb128f8dd700fa165d
https://europepmc.org/articles/PMC7596148/
https://europepmc.org/articles/PMC7596148/
Autor:
Marianna, Pepona, Peter, Balogh, Daniel F, Puleri, William F, Hynes, Claire, Robertson, Karen, Dubbin, Javier, Alvarado, Monica L, Moya, Amanda, Randles
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: The biological and mechanical properties of circulating tumor cells (CTCs) in combination with the hemodynamics affect the preference of metastatic sites in the vasculature. Despite the extensive literature on the effects of biological
Publikováno v:
Cell Mol Bioeng
IntroductionThe generation of affinity reagents that bind native membrane proteins with high specificity remains challenging. Mostin vitroselection paradigms utilize different cell types for positive and negative rounds of selection (where the positi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c5e618e90f1f22415653e90d2eec0b